| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Testicular Diseases | D013733 | 15 associated lipids |
| Occupational Diseases | D009784 | 42 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Brain Diseases | D001927 | 27 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Demyelinating Diseases | D003711 | 15 associated lipids |
2,5-hexanedione
2,5-hexanedione is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 1519 references associated with 2,5-hexanedione in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for 2,5-hexanedione
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 2,5-hexanedione
NCBI Entrez Crosslinks
All references with 2,5-hexanedione
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wang Z et al. | 2,5-hexanedione downregulates nerve growth factor and induces neuron apoptosis in the spinal cord of rats via inhibition of the PI3K/Akt signaling pathway. | 2017 | PLoS ONE | pmid:28654704 |
| Li S et al. | Taurine inhibits 2,5-hexanedione-induced oxidative stress and mitochondria-dependent apoptosis in PC12 cells. | 2017 | Ind Health | pmid:27840369 |
| Dere E et al. | From the Cover: Sperm Molecular Biomarkers Are Sensitive Indicators of Testicular Injury following Subchronic Model Toxicant Exposure. | 2016 | Toxicol. Sci. | pmid:27466211 |
| Liu S et al. | 2,5-hexanedione induced apoptosis of rat bone marrow mesenchymal stem cells by reactive oxygen species. | 2016 | J Occup Health | pmid:27010086 |
| Ma SX et al. | Impaired expression of neuronal nitric oxide synthase in the gracile nucleus is involved in neuropathic changes in Zucker Diabetic Fatty rats with and without 2,5-hexanedione intoxication. | 2016 | Neurosci. Res. | pmid:26519861 |
| Chen R et al. | 2,5-hexanedione induced apoptosis in mesenchymal stem cells from rat bone marrow via mitochondria-dependent caspase-3 pathway. | 2015 | Ind Health | pmid:25739802 |
| LoPachin RM and Gavin T | Toxic neuropathies: Mechanistic insights based on a chemical perspective. | 2015 | Neurosci. Lett. | pmid:25218479 |
| Gagnaire F and Boucard S | Olfactory mucosal necrosis in rats following acute intraperitoneal administration of 1,2-diethylbenzene, 1,2-diacetylbenzene and 2,5-hexanedione. | 2014 | Neurotoxicology | pmid:24373906 |
| Catlin NR et al. | The stage-specific testicular germ cell apoptotic response to low-dose X-irradiation and 2,5-hexanedione combined exposure. I: Validation of the laser capture microdissection method for qRT-PCR array application. | 2014 | Toxicol Pathol | pmid:24717900 |
| Catlin NR et al. | The stage-specific testicular germ cell apoptotic response to low-dose radiation and 2,5-hexanedione combined exposure. II: qRT-PCR array analysis reveals dose dependent adaptive alterations in the apoptotic pathway. | 2014 | Toxicol Pathol | pmid:24670816 |
| Zhu MX et al. | [Formation of pyrrole adducts in 2,5-hexanedione-containing human serum cultured in vitro]. | 2013 | Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi | pmid:24053965 |
| Yin H et al. | Correlation between levels of 2, 5-hexanedione and pyrrole adducts in tissues of rats exposure to n-hexane for 5-days. | 2013 | PLoS ONE | pmid:24098756 |
| Zhang W et al. | Apoptosis of rat ovarian granulosa cells by 2,5-hexanedione in vitro and its relevant gene expression. | 2013 | J Appl Toxicol | pmid:22337490 |
| Erdos Z et al. | Inhibin B response to testicular toxicants hexachlorophene, ethane dimethane sulfonate, di-(n-butyl)-phthalate, nitrofurazone, DL-ethionine, 17-alpha ethinylestradiol, 2,5-hexanedione, or carbendazim following short-term dosing in male rats. | 2013 | Birth Defects Res. B Dev. Reprod. Toxicol. | pmid:23348767 |
| Pacheco SE et al. | Optimization of a filter-lysis protocol to purify rat testicular homogenates for automated spermatid counting. | 2012 Sep-Oct | J. Androl. | pmid:22240558 |
| Giorgio V et al. | The effects of idebenone on mitochondrial bioenergetics. | 2012 | Biochim. Biophys. Acta | pmid:22086148 |
| Hanai Y et al. | Analysis of volatile organic compounds released from human lung cancer cells and from the urine of tumor-bearing mice. | 2012 | Cancer Cell Int. | pmid:22364569 |
| Sun Y et al. | 2,5-Hexanedione induces human ovarian granulosa cell apoptosis through BCL-2, BAX, and CASPASE-3 signaling pathways. | 2012 | Arch. Toxicol. | pmid:21901545 |
| Song F et al. | 2,5-hexanedione altered the degradation of low-molecular-weight neurofilament in rat nerve tissues. | 2012 | Food Chem. Toxicol. | pmid:22967723 |
| Pacheco SE et al. | Sperm mRNA transcripts are indicators of sub-chronic low dose testicular injury in the Fischer 344 rat. | 2012 | PLoS ONE | pmid:22952946 |