| MeSH term | MeSH ID | Detail |
|---|---|---|
| Genetic Diseases, X-Linked | D040181 | 2 associated lipids |
| Lactose Intolerance | D007787 | 2 associated lipids |
| Circoviridae Infections | D018173 | 2 associated lipids |
| Spirochaetales Infections | D013145 | 2 associated lipids |
| Lymphopenia | D008231 | 2 associated lipids |
| Pneumonia, Viral | D011024 | 3 associated lipids |
| Melanosis | D008548 | 4 associated lipids |
| Pregnancy Complications, Neoplastic | D011252 | 4 associated lipids |
| Exocrine Pancreatic Insufficiency | D010188 | 6 associated lipids |
| Constipation | D003248 | 8 associated lipids |
Linoleic acid
Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoleic acid?
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoleic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with Linoleic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoleic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoleic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoleic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Oh JM et al. | Effects of palmitic acid on TNF-α-induced cytotoxicity in SK-Hep-1 cells. | 2012 | Toxicol In Vitro | pmid:22683933 |
| Chiou TY et al. | Extraction of defatted rice bran with subcritical aqueous acetone. | 2012 | Biosci. Biotechnol. Biochem. | pmid:22878207 |
| Wolańska D and Kłosiewicz-Latoszek L | [Fatty acids intake and serum lipids profile in overweighted and obese adults]. | 2012 | Rocz Panstw Zakl Hig | pmid:22928362 |
| Jadoon A et al. | Associations of polyunsaturated fatty acids with residual depression or anxiety in older people with major depression. | 2012 | J Affect Disord | pmid:22113178 |
| Järvinen R et al. | Associations of dietary polyunsaturated fatty acids with bone mineral density in elderly women. | 2012 | Eur J Clin Nutr | pmid:22113249 |
| Nandi S et al. | Effect of prostaglandin producing modulators on in vitro growth of buffalo uterine epithelial cells. | 2012 | Theriogenology | pmid:22115808 |
| Xue C et al. | Differences in lipid characteristics among populations: low-temperature adaptability of ayu, Plecoglossus altivelis. | 2012 | Lipids | pmid:22120618 |
| Msika O et al. | NGF blocks polyunsaturated fatty acids biosynthesis in n-3 fatty acid-supplemented PC12 cells. | 2012 | Biochim. Biophys. Acta | pmid:22564256 |
| Ozcan MM et al. | Characteristics of grape seed and oil from nine Turkish cultivars. | 2012 | Nat. Prod. Res. | pmid:22132714 |
| Moodley R et al. | Elemental composition and fatty acid profile of the edible fruits of Amatungula (Carissa macrocarpa) and impact of soil quality on chemical characteristics. | 2012 | Anal. Chim. Acta | pmid:22632042 |
| Jung CH et al. | The role of Rho/Rho-kinase pathway in the expression of ICAM-1 by linoleic acid in human aortic endothelial cells. | 2012 | Inflammation | pmid:22124782 |
| Macaluso F et al. | Effect of conjugated linoleic acid on testosterone levels in vitro and in vivo after an acute bout of resistance exercise. | 2012 | J Strength Cond Res | pmid:22614148 |
| Shah BP et al. | TRPM5 is critical for linoleic acid-induced CCK secretion from the enteroendocrine cell line, STC-1. | 2012 | Am. J. Physiol., Cell Physiol. | pmid:21998136 |
| Saracoglu HT et al. | Evaluation of oil content and fatty acid composition of five endemic Bupleurum species growing in the Central Anatolia region of Turkey. | 2012 | Nat. Prod. Res. | pmid:21870933 |
| Lee S et al. | Significant inverse associations of serum n-6 fatty acids with plasma plasminogen activator inhibitor-1. | 2012 | Br. J. Nutr. | pmid:21846428 |
| Gu L et al. | Chemical and cellular antioxidant activity of two novel peptides designed based on glutathione structure. | 2012 | Food Chem. Toxicol. | pmid:22940538 |
| Rodrigues HG et al. | Oral administration of oleic or linoleic acid accelerates the inflammatory phase of wound healing. | 2012 | J. Invest. Dermatol. | pmid:21881592 |
| Nurachman Z et al. | Oil from the tropical marine benthic-diatom Navicula sp. | 2012 | Appl. Biochem. Biotechnol. | pmid:22926527 |
| Huang FC and Schwab W | Overexpression of hydroperoxide lyase, peroxygenase and epoxide hydrolase in tobacco for the biotechnological production of flavours and polymer precursors. | 2012 | Plant Biotechnol. J. | pmid:22967031 |
| Koch C et al. | Linoleic acid positioning in psi factor producing oxygenase A, a fusion protein with an atypical cytochrome P450 activity. | 2012 | FEBS J. | pmid:21920024 |
| Osuji GO et al. | Molecular modeling of metabolism for allergen-free low linoleic acid peanuts. | 2012 | Appl. Biochem. Biotechnol. | pmid:22918723 |
| Kim YS et al. | In vitro protective effects of Thymus quinquecostatus Celak extracts on t-BHP-induced cell damage through antioxidant activity. | 2012 | Food Chem. Toxicol. | pmid:22921350 |
| Mukherjee S et al. | NAD(P)H cytochrome b5 oxidoreductase deficiency in Leishmania major results in impaired linoleate synthesis followed by increased oxidative stress and cell death. | 2012 | J. Biol. Chem. | pmid:22923617 |
| Le Maux S et al. | β-Lactoglobulin as a molecular carrier of linoleate: characterization and effects on intestinal epithelial cells in vitro. | 2012 | J. Agric. Food Chem. | pmid:22924475 |
| Dubey V et al. | Appraisal of conjugated linoleic acid production by probiotic potential of Pediococcus spp. GS4. | 2012 | Appl. Biochem. Biotechnol. | pmid:22971829 |
| Gursoy O et al. | The effect of using different probiotic cultures on conjugated linoleic acid (CLA) concentration and fatty acid composition of white pickle cheese. | 2012 | Int J Food Sci Nutr | pmid:22166042 |
| Figueiredo JA et al. | Facile synthesis of oxo-/thioxopyrimidines and tetrazoles C-C linked to sugars as novel non-toxic antioxidant acetylcholinesterase inhibitors. | 2012 | Carbohydr. Res. | pmid:22153708 |
| Sajid ZI et al. | Antioxidant, antimicrobial properties and phenolics of different solvent extracts from bark, leaves and seeds of Pongamia pinnata (L.) Pierre. | 2012 | Molecules | pmid:22466852 |
| Shindo T et al. | Effective induction of oral anaphylaxis to ovalbumin in mice sensitized by feeding of the antigen with aid of oil emulsion and salicylate. | 2012 | J Toxicol Sci | pmid:22467021 |
| Shimomoto T et al. | Advanced glycation end products (AGE) induce the receptor for AGE in the colonic mucosa of azoxymethane-injected Fischer 344 rats fed with a high-linoleic acid and high-glucose diet. | 2012 | J. Gastroenterol. | pmid:22467055 |
| Gören AC et al. | Fatty acid composition and chemotaxonomic evaluation of species of Stachys. | 2012 | Nat. Prod. Res. | pmid:21859257 |
| Zein CO et al. | Pentoxifylline decreases oxidized lipid products in nonalcoholic steatohepatitis: new evidence on the potential therapeutic mechanism. | 2012 | Hepatology | pmid:22505276 |
| Takahashi T et al. | Effect of linoleic acid albumin in a dilution solution and long-term equilibration for freezing of bovine spermatozoa with poor freezability. | 2012 | Reprod. Domest. Anim. | pmid:21635578 |
| Liu X et al. | Method for screening of bacterial strains biosynthesizing specific conjugated linoleic acid isomers. | 2012 | J. Agric. Food Chem. | pmid:22946615 |
| Eserian JK et al. | Effects of polyunsaturated fatty acids on cocaine-conditioned place preference in mice. | 2012 | Nutr Neurosci | pmid:22390908 |
| Fei J et al. | ω-6 lipids regulate PPAR turnover via reciprocal switch between PGC-1 alpha and ubiquitination. | 2012 | Atherosclerosis | pmid:22464285 |
| Jarvis MF | Cytochrome P450 mediated linoleic acid metabolism in peripheral inflammatory nociception. | 2012 | Pain | pmid:22681878 |
| Ren HT et al. | Influence of dietary fatty acids on muscle fatty acid composition and expression levels of Δ6 desaturase-like and Elovl5-like elongase in common carp (Cyprinus carpio var. Jian). | 2012 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:22677415 |
| Angell RJ et al. | Fish oil supplementation maintains adequate plasma arachidonate in cats, but similar amounts of vegetable oils lead to dietary arachidonate deficiency from nutrient dilution. | 2012 | Nutr Res | pmid:22652378 |
| Burrows T et al. | A comparative validation of a child food frequency questionnaire using red blood cell membrane fatty acids. | 2012 | Eur J Clin Nutr | pmid:22378224 |
| Vanek VW et al. | A.S.P.E.N. position paper: Clinical role for alternative intravenous fat emulsions. | 2012 | Nutr Clin Pract | pmid:22378798 |
| Shin D et al. | Effects of dietary combination of n-3 and n-9 fatty acids on the deposition of linoleic and arachidonic acid in broiler chicken meats. | 2012 | Poult. Sci. | pmid:22399741 |
| Chen MH and Nelson EB | Microbial-induced carbon competition in the spermosphere leads to pathogen and disease suppression in a municipal biosolids compost. | 2012 | Phytopathology | pmid:22352306 |
| He M et al. | Effect of dietary fat blend enriched in oleic or linoleic acid and monensin supplementation on dairy cattle performance, milk fatty acid profiles, and milk fat depression. | 2012 | J. Dairy Sci. | pmid:22365227 |
| Castro LF et al. | Functional desaturase Fads1 (Δ5) and Fads2 (Δ6) orthologues evolved before the origin of jawed vertebrates. | 2012 | PLoS ONE | pmid:22384110 |
| Li KL et al. | Characterization of cumulus expansion-inhibiting factor (CEIF) in goat follicles. | 2012 | Biol. Reprod. | pmid:22402961 |
| Dall'Asta C et al. | Role of maize hybrids and their chemical composition in Fusarium infection and fumonisin production. | 2012 | J. Agric. Food Chem. | pmid:22409349 |
| Mulligan CM et al. | Dietary linoleate preserves cardiolipin and attenuates mitochondrial dysfunction in the failing rat heart. | 2012 | Cardiovasc. Res. | pmid:22411972 |
| Gull J et al. | Variation in antioxidant attributes at three ripening stages of guava (Psidium guajava L.) fruit from different geographical regions of Pakistan. | 2012 | Molecules | pmid:22418924 |
| Okui T et al. | Cis-9,trans-11-conjugated linoleic acid promotes neuronal differentiation through regulation of Hes6 mRNA and cell cycle in cultured neural stem cells. | 2011 Sep-Oct | Prostaglandins Leukot. Essent. Fatty Acids | pmid:21723718 |