Linoleic acid

Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.

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Introduction

To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoleic acid?

Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoleic acid

PubChem Associated disorders and diseases

What pathways are associated with Linoleic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with Linoleic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoleic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoleic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoleic acid

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Authors Title Published Journal PubMed Link
Fu J et al. Hypolipidemic activity in Sprague-Dawley rats and constituents of a novel natural vegetable oil from Cornus wilsoniana fruits. 2012 J. Food Sci. pmid:22747885
Sabir A et al. The fatty acid and tocopherol constituents of the seed oil extracted from 21 grape varieties (Vitis spp.). 2012 J. Sci. Food Agric. pmid:22271548
Ross GR et al. Fatty acid profile of pig meat after probiotic administration. 2012 J. Agric. Food Chem. pmid:22506842
Ties P and Barringer S Influence of lipid content and lipoxygenase on flavor volatiles in the tomato peel and flesh. 2012 J. Food Sci. pmid:22757705
Matsubara T et al. TGF-β-SMAD3 signaling mediates hepatic bile acid and phospholipid metabolism following lithocholic acid-induced liver injury. 2012 J. Lipid Res. pmid:23034213
Wajid NA and Halpern BP Oral cavity discrimination of vapor-phase long-chain 18-carbon fatty acids. 2012 Chem. Senses pmid:22459162
Ruiz M et al. A cardiac-specific robotized cellular assay identified families of human ligands as inducers of PGC-1α expression and mitochondrial biogenesis. 2012 PLoS ONE pmid:23056435
Saei-Dehkordi SS et al. Chemical composition and antioxidative activity of Echinophora platyloba DC. essential oil, and its interaction with natural antimicrobials against food-borne pathogens and spoilage organisms. 2012 J. Food Sci. pmid:23106123
Garcia CV et al. Characterisation of bound volatile compounds of a low flavour kiwifruit species: Actinidia eriantha. 2012 Food Chem pmid:23107675
Beck JJ et al. Generation of the volatile spiroketals conophthorin and chalcogran by fungal spores on polyunsaturated fatty acids common to almonds and pistachios. 2012 J. Agric. Food Chem. pmid:23153034
Cortie CH and Else PL Dietary docosahexaenoic Acid (22:6) incorporates into cardiolipin at the expense of linoleic Acid (18:2): analysis and potential implications. 2012 Int J Mol Sci pmid:23203135
Sauerwald UC et al. Effect of different levels of docosahexaenoic acid supply on fatty acid status and linoleic and α-linolenic acid conversion in preterm infants. 2012 J. Pediatr. Gastroenterol. Nutr. pmid:22008957
Hu ZP et al. Metabonomic profiling of TASTPM transgenic Alzheimer's disease mouse model. 2012 J. Proteome Res. pmid:23078235
Heinze VM and Actis AB Dietary conjugated linoleic acid and long-chain n-3 fatty acids in mammary and prostate cancer protection: a review. 2012 Int J Food Sci Nutr pmid:21762028
Celia C et al. Ethosomes® and transfersomes® containing linoleic acid: physicochemical and technological features of topical drug delivery carriers for the potential treatment of melasma disorders. 2012 Biomed Microdevices pmid:21960035
Buchhaupt M et al. Synthesis of green note aroma compounds by biotransformation of fatty acids using yeast cells coexpressing lipoxygenase and hydroperoxide lyase. 2012 Appl. Microbiol. Biotechnol. pmid:21789493
Yumrutas O et al. Phenolic acid contents, essential oil compositions and antioxidant activities of two varieties of Salvia euphratica from Turkey. 2012 Nat. Prod. Res. pmid:21995274
King NP et al. Characterisation of a cell wall-anchored protein of Staphylococcus saprophyticus associated with linoleic acid resistance. 2012 BMC Microbiol. pmid:22243671
Tyagi A et al. Attenuation of colonic inflammation by partial replacement of dietary linoleic acid with α-linolenic acid in a rat model of inflammatory bowel disease. 2012 Br. J. Nutr. pmid:22243775
Zhou H et al. Purification and characterization of a novel ~18 kDa antioxidant protein from Ginkgo biloba seeds. 2012 Molecules pmid:23519252
Kurotani K et al. High levels of stearic acid, palmitoleic acid, and dihomo-γ-linolenic acid and low levels of linoleic acid in serum cholesterol ester are associated with high insulin resistance. 2012 Nutr Res pmid:23084639
Trevizan L et al. Maintenance of arachidonic acid and evidence of Δ5 desaturation in cats fed γ-linolenic and linoleic acid enriched diets. 2012 Lipids pmid:22249937
Zhu X et al. Release property and antioxidant effectiveness of tocopherol-incorporated LDPE/PP blend films. 2012 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:22257167
Tanaka R et al. Prenylated acylphloroglucinol derivatives: isoprenomics-based design, syntheses and antioxidative activities. 2012 Adv. Exp. Med. Biol. pmid:22259110
Raatz SK et al. Total dietary fat and fatty acid content modifies plasma phospholipid fatty acids, desaturase activity indices, and urinary prostaglandin E in women. 2012 Nutr Res pmid:22260857
Burstein S et al. N-Amino acid linoleoyl conjugates: anti-inflammatory activities. 2012 Bioorg. Med. Chem. Lett. pmid:22217875
Mormile R et al. Linoleic acid and colorectal cancer cell growth suppression: is the deregulation of mitochondrial survivin the key factor? 2012 Int J Colorectal Dis pmid:22231621
Luévano-Martínez LA et al. A critical tyrosine residue determines the uncoupling protein-like activity of the yeast mitochondrial oxaloacetate carrier. 2012 Biochem. J. pmid:22236206
Jorge AT et al. Schinus terebinthifolius Raddi extract and linoleic acid from Passiflora edulis synergistically decrease melanin synthesis in B16 cells and reconstituted epidermis. 2012 Int J Cosmet Sci pmid:22738140
Manzoor M et al. Variation in minerals, phenolics and antioxidant activity of peel and pulp of different varieties of peach (Prunus persica L.) fruit from Pakistan. 2012 Molecules pmid:22728349
Tao XM et al. Enhanced anticancer activity of gemcitabine coupling with conjugated linoleic acid against human breast cancer in vitro and in vivo. 2012 Eur J Pharm Biopharm pmid:22728546
Dundar A et al. Antioxidant properties, chemical composition and nutritional value of Terfezia boudieri (Chatin) from Turkey. 2012 Food Sci Technol Int pmid:22773542
Al-Said MS et al. Edible oils for liver protection: hepatoprotective potentiality of Moringa oleifera seed oil against chemical-induced hepatitis in rats. 2012 J. Food Sci. pmid:22757719
Toomik P et al. The effect of tenderizing acids on linoleic acid oxidation during marination of pork. 2012 Meat Sci. pmid:22762994
Amoo SO et al. Antioxidant and acetylcholinesterase-inhibitory properties of long-term stored medicinal plants. 2012 BMC Complement Altern Med pmid:22769046
Park EY et al. Effects of peptide fractions with different isoelectric points from wheat gluten hydrolysates on lipid oxidation in pork meat patties. 2012 J. Agric. Food Chem. pmid:22747172
Pestana JM et al. Effect of slaughter season and muscle type on the fatty acid composition, including conjugated linoleic acid isomers, and nutritional value of intramuscular fat in organic beef. 2012 J. Sci. Food Agric. pmid:22473659
Kowalska A et al. Impact of diets with different proportions of linseed and sunflower oils on the growth, liver histology, immunological and chemical blood parameters, and proximate composition of pikeperch Sander lucioperca (L.). 2012 Fish Physiol. Biochem. pmid:21656178
Martínez Marín AL et al. Effects of feeding increasing dietary levels of high oleic or regular sunflower or linseed oil on fatty acid profile of goat milk. 2012 J. Dairy Sci. pmid:22459841
Maqbool A et al. Relation between dietary fat intake type and serum fatty acid status in children with cystic fibrosis. 2012 J. Pediatr. Gastroenterol. Nutr. pmid:22699835
da Silva Acosta D et al. Fullerene and omega-3 and omega-6 fatty acids on fish brain antioxidant status. 2012 Fish Physiol. Biochem. pmid:22451341
Li D et al. Antitumor efficacy of a novel CLA-PTX microemulsion against brain tumors: in vitro and in vivo findings. 2012 Int J Nanomedicine pmid:23269869
Tanigai T et al. Docosahexaenoic acid exerts anti-inflammatory action on human eosinophils through peroxisome proliferator-activated receptor-independent mechanisms. 2012 Int. Arch. Allergy Immunol. pmid:22487606
Romano R et al. Comparison of the frying performance of olive oil and palm superolein. 2012 J. Food Sci. pmid:22490166
Manosroi A et al. Transfollicular enhancement of gel containing cationic niosomes loaded with unsaturated fatty acids in rice (Oryza sativa) bran semi-purified fraction. 2012 Eur J Pharm Biopharm pmid:22490981
Cerretani L et al. DSC evaluation of extra virgin olive oil stability under accelerated oxidative test: effect of fatty acid composition and phenol contents. 2012 J Oleo Sci pmid:22687775
Hill S et al. Small amounts of isotope-reinforced polyunsaturated fatty acids suppress lipid autoxidation. 2012 Free Radic. Biol. Med. pmid:22705367
Roongpisuthipong W et al. Essential fatty acid deficiency while a patient receiving fat regimen total parenteral nutrition. 2012 BMJ Case Rep pmid:22707694
Wiebe MG et al. Lipid production in batch and fed-batch cultures of Rhodosporidium toruloides from 5 and 6 carbon carbohydrates. 2012 BMC Biotechnol. pmid:22646156
Itakura H et al. The change in low-density lipoprotein cholesterol concentration is positively related to plasma docosahexaenoic acid but not eicosapentaenoic acid. 2012 J. Atheroscler. Thromb. pmid:22653220