| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Tuberculosis | D014376 | 20 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Otitis Externa | D010032 | 8 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
Linoleic acid
Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoleic acid?
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoleic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with Linoleic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoleic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoleic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoleic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Garcia Zevallos M and Farkas T | Manipulation of plasma membrane physical state affects desaturase activity in rat lymphocytes. | 1989 | Arch. Biochem. Biophys. | pmid:2786374 |
| Bates D | Lipids and multiple sclerosis. | 1989 | Biochem. Soc. Trans. | pmid:2546837 |
| Tchervenkov JI et al. | The effect of donor-specific blood transfusion, cyclosporine, and dietary prostaglandin precursors on rat cardiac allograft survival. II. Effectiveness of a 24-hour induction period with DST and CsA in inducing long-term graft survival. | 1989 | Transplantation | pmid:2643225 |
| Mcgregor L et al. | Effects of dietary linoleic acid and gamma linolenic acid on platelets of patients with multiple sclerosis. | 1989 | Acta Neurol. Scand. | pmid:2782038 |
| Perez RV et al. | Augmentation of donor-specific transfusion and cyclosporine effects with dietary linoleic acid. | 1989 | Transplantation | pmid:2660353 |
| Park JH et al. | Effects of dietary linoleic acid on mucosal adaptation after small bowel resection. | 1989 | Digestion | pmid:2612750 |
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| Kurganov BI et al. | Kinetics of soybean lipoxygenase reaction in hydrated reversed micelles. | 1989 | Biochimie | pmid:2474334 |
| Anderson GJ and Connor WE | On the demonstration of omega-3 essential-fatty-acid deficiency in humans. | 1989 | Am. J. Clin. Nutr. | pmid:2494878 |
| Byczkowski JZ and Kulkarni AP | Lipoxygenase-catalyzed epoxidation of benzo(a)pyrene-7,8-dihydrodiol. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2494999 |
| Hamazaki S et al. | Oxygen reduction and lipid peroxidation by iron chelates with special reference to ferric nitrilotriacetate. | 1989 | Arch. Biochem. Biophys. | pmid:2500058 |
| Matsuzaki A et al. | Mechanism of selective killing by dilinoleoylglycerol of cells transformed by the E1A gene of adenovirus type 12. | 1989 | Cancer Res. | pmid:2529026 |
| Hicks M et al. | Increase in crosslinking of nonenzymatically glycosylated collagen induced by products of lipid peroxidation. | 1989 | Arch. Biochem. Biophys. | pmid:2492180 |
| Furth EE et al. | The effect of endogenous essential and nonessential fatty acids on the uptake and subsequent agonist-induced release of arachidonate. | 1989 | J. Biol. Chem. | pmid:2553711 |
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| Bolton-Smith C et al. | The effect of dietary linoleic acid on rat platelet sialic acid. | 1989 | Biochim. Biophys. Acta | pmid:2775771 |
| Zevenbergen JL and Houtsmuller UM | Effect of dietary fats on linoleic acid metabolism. A radiolabel study in rats. | 1989 | Biochim. Biophys. Acta | pmid:2713382 |
| Levay-Young BK and Nandi S | Spermidine is necessary for, but not the only mediator of, linoleic acid-stimulated alpha-casein accumulation in mouse mammary epithelial cells. | 1989 | Endocrinology | pmid:2759031 |
| Berlin E et al. | Dietary fat and hormonal effects on erythrocyte membrane fluidity and lipid composition in adult women. | 1989 | Metab. Clin. Exp. | pmid:2761416 |
| Reddy SR et al. | Effect of linoleic acid infusion on blood pressure in normotensive and hypertensive rats. | 1989 | Am. J. Physiol. | pmid:2764141 |
| Stein O et al. | Modification of cellular fatty acid composition of Hep-G2 cells: effect of antioxidants on cholesterol esterification and secretion. | 1989 | Biochim. Biophys. Acta | pmid:2730885 |
| Reinaud O et al. | Oxidative metabolism of linoleic acid by human leukocytes. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2735926 |
| Cunnane SC et al. | Essential fatty acid and lipid profiles in plasma and erythrocytes in patients with multiple sclerosis. | 1989 | Am. J. Clin. Nutr. | pmid:2801584 |
| Furr HC et al. | The effect of dietary fatty acid composition on liver retinyl ester (vitamin A ester) composition in the rat. | 1989 | J. Nutr. | pmid:2703916 |
| Chen Q et al. | Hydrolysis of triacylglycerol arachidonic and linoleic acid ester bonds by human pancreatic lipase and carboxyl ester lipase. | 1989 | Biochim. Biophys. Acta | pmid:2503032 |
| Chapkin RS et al. | Linoleic acid metabolism in metastatic and nonmetastatic murine mammary tumor cells. | 1989 | Cancer Res. | pmid:2503244 |
| Hamazaki T et al. | Urinary excretion of PGI2/3-M and recent N-6/3 fatty acid intake. | 1989 | Prostaglandins | pmid:2503856 |
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| Schneider YJ | Optimisation of hybridoma cell growth and monoclonal antibody secretion in a chemically defined, serum- and protein-free culture medium. | 1989 | J. Immunol. Methods | pmid:2644356 |
| Watkins BA | Influences of biotin deficiency and dietary trans-fatty acids on tissue lipids in chickens. | 1989 | Br. J. Nutr. | pmid:2923859 |
| Girón MD et al. | Changes in lipid composition and desaturase activities of duodenal mucosa induced by dietary fat. | 1990 | Biochim. Biophys. Acta | pmid:2369586 |
| Appel MJ et al. | Azaserine-induced pancreatic carcinogenesis in rats: promotion by a diet rich in saturated fat and inhibition by a standard laboratory chow. | 1990 | Cancer Lett. | pmid:2257542 |
| Pal S and Davis PJ | N-3 polyunsaturated fatty acids enhance cholesterol efflux from human fibroblasts in culture. | 1990 | Biochem. Biophys. Res. Commun. | pmid:2260969 |
| Kawada H et al. | Improved maintenance of adult rat alveolar type II cell differentiation in vitro: effect of serum-free, hormonally defined medium and a reconstituted basement membrane. | 1990 | Am. J. Respir. Cell Mol. Biol. | pmid:2363935 |
| Kestin M et al. | n-3 fatty acids of marine origin lower systolic blood pressure and triglycerides but raise LDL cholesterol compared with n-3 and n-6 fatty acids from plants. | 1990 | Am. J. Clin. Nutr. | pmid:1971991 |
| Lipids and multiple sclerosis. | 1990 | Lancet | pmid:1973215 | |
| Anel A et al. | Fatty acid metabolism in human lymphocytes. II. Activation of fatty acid desaturase-elongase systems during blastic transformation. | 1990 | Biochim. Biophys. Acta | pmid:2114179 |
| Moore SA et al. | Role of the blood-brain barrier in the formation of long-chain omega-3 and omega-6 fatty acids from essential fatty acid precursors. | 1990 | J. Neurochem. | pmid:2115069 |
| Nikolaev V et al. | Stereochemical nature of the products of linoleic acid oxidation catalyzed by lipoxygenases from potato and soybean. | 1990 | Biochem. Biophys. Res. Commun. | pmid:2116790 |
| Bedotti R et al. | Stimulatory effect of serum albumin on the proliferation of serum-free SV40-transformed Balb/c 3T3 cells. | 1990 | Biochim. Biophys. Acta | pmid:2163687 |
| Mullarkey CJ et al. | Free radical generation by early glycation products: a mechanism for accelerated atherogenesis in diabetes. | 1990 | Biochem. Biophys. Res. Commun. | pmid:2176495 |
| Hernández-Caselles T et al. | Stability of liposomes on long term storage. | 1990 | J. Pharm. Pharmacol. | pmid:1979618 |
| Hori T et al. | Growth inhibition of human fibroblasts by epidermal growth factor in the presence of arachidonic acid. | 1990 | Biochem. Biophys. Res. Commun. | pmid:2114113 |
| Hjelte L et al. | Absorption and metabolism of [3H]arachidonic and [14C]linoleic acid in essential fatty acid-deficient rats. | 1990 | Am. J. Physiol. | pmid:2115302 |