| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Tuberculosis | D014376 | 20 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Otitis Externa | D010032 | 8 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
Linoleic acid
Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoleic acid?
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoleic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with Linoleic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoleic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoleic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoleic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kwok CF et al. | Linoleic acid and oleic acid increase the endothelin-1 binding and action in cultured rat aortic smooth muscle cells. | 2000 | Metab. Clin. Exp. | pmid:11092498 |
| Ueno S et al. | Polymorphism of linoleic acid (cis-9, cis-12-octadecadienoic acid) and alpha-linolenic acid (cis-9, cis-12, cis-15-octadecatrienoic acid). | 2000 | Chem. Phys. Lipids | pmid:11090846 |
| Mizushina Y et al. | Structural homology between DNA binding sites of DNA polymerase beta and DNA topoisomerase II. | 2000 | J. Mol. Biol. | pmid:11090281 |
| Louw L | Keloids in rural black South Africans. Part 3: a lipid model for the prevention and treatment of keloid formations. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11090251 |
| Louw L and Dannhauser A | Keloids in rural black South Africans. Part 2: dietary fatty acid intake and total phospholipid fatty acid profile in the blood of keloid patients. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11090250 |
| Lehtinen P and Laakso S | Inhibition of linoleic acid oxidation by interaction with a protein-rich oat fraction. | 2000 | J. Agric. Food Chem. | pmid:11087534 |
| Grechkin AN et al. | The lipoxygenase pathway in tulip (Tulipa gesneriana): detection of the ketol route. | 2000 | Biochem. J. | pmid:11085944 |
| Hochi S et al. | Nuclear transfer in cattle : effect of linoleic acid-albumin on freezing sensitivity of enucleated oocytes. | 2000 | J. Vet. Med. Sci. | pmid:11073086 |
| Cahoon EB et al. | Formation of conjugated delta8,delta10-double bonds by delta12-oleic-acid desaturase-related enzymes: biosynthetic origin of calendic acid. | 2001 | J. Biol. Chem. | pmid:11067856 |
| Granot E et al. | Breast-fed and formula-fed infants do not differ in immunocompetent cell cytokine production despite differences in cell membrane fatty acid composition. | 2000 | Am. J. Clin. Nutr. | pmid:11063450 |
| Brynes AE et al. | Diet-induced change in fatty acid composition of plasma triacylglycerols is not associated with change in glucagon-like peptide 1 or insulin sensitivity in people with type 2 diabetes. | 2000 | Am. J. Clin. Nutr. | pmid:11063437 |
| French P et al. | Fatty acid composition, including conjugated linoleic acid, of intramuscular fat from steers offered grazed grass, grass silage, or concentrate-based diets. | 2000 | J. Anim. Sci. | pmid:11063308 |
| Ferry DR et al. | A phase II study of the 5-lipoxygenase inhibitor, CV6504, in advanced pancreatic cancer: correlation of clinical data with pharmacokinetic and pharmacodynamic endpoints. | 2000 | Ann. Oncol. | pmid:11061613 |
| Cunnane SC et al. | Specific linoleate deficiency in the rat does not prevent substantial carbon recycling from [(14)C]linoleate into sterols. | 2000 | J. Lipid Res. | pmid:11060350 |
| Surai PF et al. | Effect of long-term supplementation with arachidonic or docosahexaenoic acids on sperm production in the broiler chicken. | 2000 | J. Reprod. Fertil. | pmid:11058441 |
| Whigham LD et al. | Conjugated linoleic acid: implications for human health. | 2000 | Pharmacol. Res. | pmid:11058400 |
| Steinkamp G et al. | Energy supplements rich in linoleic acid improve body weight and essential fatty acid status of cystic fibrosis patients. | 2000 | J. Pediatr. Gastroenterol. Nutr. | pmid:11045840 |
| Soriano CR et al. | Cutaneous application of vegetable oil as a coadjutant in the nutritional management of preterm infants. | 2000 | J. Pediatr. Gastroenterol. Nutr. | pmid:11045835 |
| Moran JH et al. | Analysis of the cytotoxic properties of linoleic acid metabolites produced by renal and hepatic P450s. | 2000 | Toxicol. Appl. Pharmacol. | pmid:11042099 |
| French SJ et al. | The effects of intestinal infusion of long-chain fatty acids on food intake in humans. | 2000 | Gastroenterology | pmid:11040181 |