| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Tuberculosis | D014376 | 20 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Otitis Externa | D010032 | 8 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
Linoleic acid
Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoleic acid?
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoleic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with Linoleic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoleic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoleic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoleic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Belury MA et al. | Dietary conjugated linoleic acid modulation of phorbol ester skin tumor promotion. | 1996 | Nutr Cancer | pmid:8875552 |
| Godessart N et al. | Prostaglandin H-synthase-2 is the main enzyme involved in the biosynthesis of octadecanoids from linoleic acid in human dermal fibroblasts stimulated with interleukin-1beta. | 1996 | J. Invest. Dermatol. | pmid:8875957 |
| Lammoglia MA et al. | Effects of dietary fat and season on steroid hormonal profiles before parturition and on hormonal, cholesterol, triglycerides, follicular patterns, and postpartum reproduction in Brahman cows. | 1996 | J. Anim. Sci. | pmid:8880430 |
| Engels F et al. | Preferential formation of 13-hydroxylinoleic acid by human peripheral blood eosinophils. | 1996 | Prostaglandins | pmid:8880897 |
| Eder K and Kirchgessner M | Zinc deficiency and the desaturation of linoleic acid in rats force-fed fat-free diets. | 1996 | Biol Trace Elem Res | pmid:8886317 |
| Peet M et al. | Essential fatty acid deficiency in erythrocyte membranes from chronic schizophrenic patients, and the clinical effects of dietary supplementation. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8888126 |
| Luukkainen P et al. | Impact of solid food on plasma arachidonic and docosahexaenoic acid status of term infants at 8 months of age. | 1996 | J. Pediatr. Gastroenterol. Nutr. | pmid:8890071 |
| Avery SV et al. | Copper toxicity towards Saccharomyces cerevisiae: dependence on plasma membrane fatty acid composition. | 1996 | Appl. Environ. Microbiol. | pmid:8899983 |
| Cunnane SC | The Canadian Society for Nutritional Sciences 1995 Young Scientist Award Lecture. Recent studies on the synthesis, beta-oxidation, and deficiency of linoleate and alpha-linolenate: are essential fatty acids more aptly named indispensable or conditionally dispensable fatty acids? | 1996 | Can. J. Physiol. Pharmacol. | pmid:8909772 |
| Cunnane SC and Likhodii SS | 13C NMR spectroscopy and gas chromatograph--combustion--isotope ratio mass spectrometry: complementary applications in monitoring the metabolism of 13C-labelled polyunsaturated fatty acids. | 1996 | Can. J. Physiol. Pharmacol. | pmid:8909789 |
| Godley PA et al. | Biomarkers of essential fatty acid consumption and risk of prostatic carcinoma. | 1996 | Cancer Epidemiol. Biomarkers Prev. | pmid:8922296 |
| Mensink R | Essential and trans-fatty acids. | 1996 | Curr. Opin. Lipidol. | pmid:8925181 |
| Mutanen M and Freese R | Polyunsaturated fatty acids and platelet aggregation. | 1996 | Curr. Opin. Lipidol. | pmid:8925182 |
| Sugano M and Ikeda I | Metabolic interactions between essential and trans-fatty acids. | 1996 | Curr. Opin. Lipidol. | pmid:8925188 |
| Ranganath LR et al. | Increased mean platelet volume after oestrogen replacement therapy. | 1996 | Ann. Clin. Biochem. | pmid:8937589 |
| Shen J et al. | Macrophage-mediated 15-lipoxygenase expression protects against atherosclerosis development. | 1996 | J. Clin. Invest. | pmid:8941635 |
| Matsuo N et al. | Effects of gamma-linolenic acid and its positional isomer pinolenic acid on immune parameters of brown-Norway rats. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8951990 |
| Applegate TJ and Sell JL | Effect of dietary linoleic to linolenic acid ratio and vitamin E supplementation on vitamin E status of poults. | 1996 | Poult. Sci. | pmid:8966177 |
| Mustad VA et al. | Dietary linoleic acid increases and palmitic acid decreases hepatic LDL receptor protein and mRNA abundance in young pigs. | 1996 | J. Lipid Res. | pmid:8978483 |
| Pregnolato P et al. | Effect of diets containing different amounts of precursor and derivative fatty acids on serum TXB2. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8981629 |