Linoleic acid

Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.

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Introduction

To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoleic acid?

Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoleic acid

PubChem Associated disorders and diseases

What pathways are associated with Linoleic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with Linoleic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoleic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoleic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoleic acid

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Authors Title Published Journal PubMed Link
Banfi C et al. Linoleic acid enhances the secretion of plasminogen activator inhibitor type 1 by HepG2 cells. 1997 J. Lipid Res. pmid:9186904
Memoli S et al. Diffusible melanin-related metabolites are potent inhibitors of lipid peroxidation. 1997 Biochim. Biophys. Acta pmid:9187303
Ek BA et al. Fatty acid binding proteins reduce 15-lipoxygenase-induced oxygenation of linoleic acid and arachidonic acid. 1997 Biochim. Biophys. Acta pmid:9187305
Berry H et al. Excess substrate inhibition of soybean lipoxygenase-1 is mainly oxygen-dependent. 1997 FEBS Lett. pmid:9188786
Peres CM et al. Transference of fatty acids from macrophages to lymphocytes in culture. 1997 Biochem. Soc. Trans. pmid:9191389
Sanderson P et al. Dietary fish oil diminishes the antigen presentation activity of rat dendritic cells. 1997 Biochem. Soc. Trans. pmid:9191396
Sharpe M et al. Ligation, inhibition, and activation of cytochrome c oxidase by fatty acids. 1997 Biochem. Cell Biol. pmid:9192076
Petrek JA et al. Fatty acid composition of adipose tissue, an indication of dietary fatty acids, and breast cancer prognosis. 1997 J. Clin. Oncol. pmid:9193329
Sauer LA et al. Dietary linoleic acid intake controls the arterial blood plasma concentration and the rates of growth and linoleic acid uptake and metabolism in hepatoma 7288CTC in Buffalo rats. 1997 J. Nutr. pmid:9202100
Schut HA et al. DNA adducts of heterocyclic amines: formation, removal and inhibition by dietary components. 1997 Mutat. Res. pmid:9202755
Yehuda S et al. Essential fatty acid preparation improves biochemical and cognitive functions in experimental allergic encephalomyelitis rats. 1997 Eur. J. Pharmacol. pmid:9203563
Stein CA Controversies in the cellular pharmacology of oligodeoxynucleotides. 1997 Antisense Nucleic Acid Drug Dev. pmid:9212912
Durgam VR and Fernandes G The growth inhibitory effect of conjugated linoleic acid on MCF-7 cells is related to estrogen response system. 1997 Cancer Lett. pmid:9215854
Jira W et al. Increased levels of lipid oxidation products in low density lipoproteins of patients suffering from rheumatoid arthritis. 1997 Chem. Phys. Lipids pmid:9219348
Quoc KP and Dubacq JP Effect of growth temperature on the biosynthesis of eukaryotic lipid molecular species by the cyanobacterium Spirulina platensis. 1997 Biochim. Biophys. Acta pmid:9219908
Shi F et al. Permeability and metabolic properties of a trophoblast cell line (HRP-1) derived from normal rat placenta. 1997 Exp. Cell Res. pmid:9223380
Haraguchi H et al. Antioxidative action of diterpenoids from Podocarpus nagi. 1997 Planta Med. pmid:9225601
Lanson M et al. Supplementation of MCF-7 cells with essential fatty acids induces the activation of protein kinase C in response to IGF-1. 1997 J Lipid Mediat Cell Signal pmid:9246607
Hannah JS et al. High fat, high cholesterol diets alter low density lipoprotein size and binding affinity in monkeys. 1997 Atherosclerosis pmid:9247355
Thomson AB et al. Nutrient uptake into undifferentiated and differentiated HT-29 cells in culture. 1997 Can. J. Physiol. Pharmacol. pmid:9250367