Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Aluf Y et al. | Alterations in striatal oxidative stress level produced by pharmacological manipulation of dopamine as shown by a novel synthetic marker molecule. | 2011 Jul-Aug | Neuropharmacology | pmid:21414328 |
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Baâtour O et al. | Salt effects on Origanum majorana fatty acid and essential oil composition. | 2011 | J. Sci. Food Agric. | pmid:21800320 |
Zened A et al. | Starch and oil in the donor cow diet and starch in substrate differently affect the in vitro ruminal biohydrogenation of linoleic and linolenic acids. | 2011 | J. Dairy Sci. | pmid:22032386 |
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Banta JP et al. | Effects of prepartum supplementation of linoleic and mid-oleic sunflower seed on cow performance, cow reproduction, and calf performance from birth through slaughter, and effects on intake and digestion in steers. | 2011 | J. Anim. Sci. | pmid:21788431 |
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Arawwawala M et al. | In vitro and in vivo evaluation of antioxidant activity of Trichosanthes cucumerina aerial parts. | 2011 | Acta. Biol. Hung. | pmid:21840826 |
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Gorissen L et al. | Linoleate isomerase activity occurs in lactic acid bacteria strains and is affected by pH and temperature. | 2011 | J. Appl. Microbiol. | pmid:21699633 |
Li M et al. | Isolation of a novel C18-Δ9 polyunsaturated fatty acid specific elongase gene from DHA-producing Isochrysis galbana H29 and its use for the reconstitution of the alternative Δ8 pathway in Saccharomyces cerevisiae. | 2011 | Biotechnol. Lett. | pmid:21538137 |
Pi F et al. | Solid-state low temperature→middle temperature phase transition of linoleic acid studied by FTIR spectroscopy. | 2011 | J Phys Chem B | pmid:21520953 |
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Pan Z et al. | Effects of linoleate on cell viability and lipid metabolic homeostasis in goose primary hepatocytes. | 2011 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:21295151 |
Tsubura A et al. | Anticancer effects of garlic and garlic-derived compounds for breast cancer control. | 2011 | Anticancer Agents Med Chem | pmid:21269259 |
Chohany LE et al. | Cationic substrates of soybean lipoxygenase-1. | 2011 | Bioorg. Chem. | pmid:21257189 |
Das R et al. | Synthesis of linoleic acid capped copper nanoparticles and their fluorescence study. | 2011 | J Fluoresc | pmid:21221748 |
Senadheera SD et al. | Effects of dietary α-linolenic acid (18:3n-3)/linoleic acid (18:2n-6) ratio on fatty acid metabolism in Murray cod (Maccullochella peelii peelii). | 2011 | J. Agric. Food Chem. | pmid:21222433 |
Liu WM et al. | Effects of linoleic acid and eicosapentaenoic acid on cell proliferation and lipid-metabolism gene expression in primary duck hepatocytes. | 2011 | Mol. Cell. Biochem. | pmid:21274596 |
Turk HF et al. | Linoleic acid and butyrate synergize to increase Bcl-2 levels in colonocytes. | 2011 | Int. J. Cancer | pmid:20232381 |