Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Peterson DB | Long-chain fatty acids and cardiovascular disease risk in non-insulin-dependent diabetes. | 1998 | Nutrition | pmid:9583379 |
Kambayashi Y et al. | Preferential hydrolysis of oxidized phosphatidylcholine in cholesterol-containing phosphatidylcholine liposome by phospholipase A2. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9588178 |
Dokko RC et al. | Cellular uptake of stearic, oleic, linoleic, and linolenic acid and their effects on synthesis and secretion of lipids in Hep-G2 cells. | 1998 | Int. J. Biochem. Cell Biol. | pmid:9597754 |
Schaloske R et al. | Fatty acids induce release of Ca2+ from acidosomal stores and activate capacitative Ca2+ entry in Dictyostelium discoideum. | 1998 | Biochem. J. | pmid:9601085 |
Geetha T et al. | Effect of triterpenes from Crataeva nurvala stem bark on lipid peroxidation in adjuvant induced arthritis in rats. | 1998 | Pharmacol. Res. | pmid:9602466 |
Kleinfeld AM et al. | Transport of long-chain native fatty acids across human erythrocyte ghost membranes. | 1998 | Biochemistry | pmid:9609694 |
Das I and Khan NS | Increased arachidonic acid induced platelet chemiluminescence indicates cyclooxygenase overactivity in schizophrenic subjects. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9610837 |
Kikuchi S et al. | Modulation of eosinophil chemotactic activities to leukotriene B4 by n-3 polyunsaturated fatty acids. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9610849 |
Ohnishi M et al. | Inhibition in vitro linoleic acid peroxidation and haemolysis by caffeoyltryptophan. | 1998 | Phytochemistry | pmid:9611825 |
Liu KL and Belury MA | Conjugated linoleic acid reduces arachidonic acid content and PGE2 synthesis in murine keratinocytes. | 1998 | Cancer Lett. | pmid:9619853 |