Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Evans SJ et al. | Dietary intake and plasma metabolomic analysis of polyunsaturated fatty acids in bipolar subjects reveal dysregulation of linoleic acid metabolism. | 2014 | J Psychiatr Res | pmid:24953860 |
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Kim JY et al. | Role of moisture on the lipid oxidation determined by D(2)O in a linoleic acid model system. | 2014 | Food Chem | pmid:24176324 |
Sponton OE et al. | Effect of limited enzymatic hydrolysis on linoleic acid binding properties of β-lactoglobulin. | 2014 | Food Chem | pmid:24176383 |
Su MH et al. | Chemical composition of seed oils in native Taiwanese Camellia species. | 2014 | Food Chem | pmid:24629982 |
Bakır T et al. | Antioxidant/prooxidant effects of α-tocopherol, quercetin and isorhamnetin on linoleic acid peroxidation induced by Cu(II) and H2O2. | 2014 | Int J Food Sci Nutr | pmid:24152374 |
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Ambrozova JV et al. | Influence of extractive solvents on lipid and fatty acids content of edible freshwater algal and seaweed products, the green Microalga Chlorella kessleri and the Cyanobacterium Spirulina platensis. | 2014 | Molecules | pmid:24566307 |
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Ogorodnikova AV et al. | Screening of divinyl ether synthase activity in nonphotosynthetic tissue of asparagales. | 2013 Mar-Apr | Dokl. Biochem. Biophys. | pmid:23657662 |
Thomas CP et al. | Steric analysis of epoxyalcohol and trihydroxy derivatives of 9-hydroperoxy-linoleic acid from hematin and enzymatic synthesis. | 2013 Feb-Mar | Chem. Phys. Lipids | pmid:23352713 |
Cheng G et al. | Relative validity of a 3 d estimated food record in German toddlers. | 2013 | Public Health Nutr | pmid:22874634 |
Stamey Lanier J et al. | Mammary uptake of fatty acids supplied by intravenous triacylglycerol infusion to lactating dairy cows. | 2013 | Lipids | pmid:23504269 |
Song Y et al. | Polyunsaturated fatty acid relatively decreases cholesterol content in THP-1 macrophage-derived foam cell: partly correlates with expression profile of CIDE and PAT members. | 2013 | Lipids Health Dis | pmid:23879935 |
Wei J et al. | Linoleic acid attenuates endothelium-derived relaxing factor production by suppressing cAMP-hydrolyzing phosphodiesterase activity. | 2013 | Circ. J. | pmid:23883876 |
Zamora-Rojas E et al. | Prediction of fatty acids content in pig adipose tissue by near infrared spectroscopy: at-line versus in-situ analysis. | 2013 | Meat Sci. | pmid:23793086 |
Harris WS et al. | Erythrocyte omega-3 fatty acids increase and linoleic acid decreases with age: observations from 160,000 patients. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:23375840 |
McPherson PA et al. | Mechanism for the enhanced peroxidation of linoleic acid by a titanium dioxide/hypochlorite system. | 2013 | Biochem. Biophys. Res. Commun. | pmid:23178466 |
Serna-Marquez N et al. | Role of LOXs and COX-2 on FAK activation and cell migration induced by linoleic acid in MDA-MB-231 breast cancer cells. | 2013 | Cell Oncol (Dordr) | pmid:23179791 |
Del Mar Bibiloni M et al. | Dietary factors associated with subclinical inflammation among girls. | 2013 | Eur J Clin Nutr | pmid:24149444 |