Linoleic acid
Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoleic acid?
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoleic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with Linoleic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Linoleic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Linoleic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoleic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Fu J et al. | Hypolipidemic activity in Sprague-Dawley rats and constituents of a novel natural vegetable oil from Cornus wilsoniana fruits. | 2012 | J. Food Sci. | pmid:22747885 |
| Ties P and Barringer S | Influence of lipid content and lipoxygenase on flavor volatiles in the tomato peel and flesh. | 2012 | J. Food Sci. | pmid:22757705 |
| Wajid NA and Halpern BP | Oral cavity discrimination of vapor-phase long-chain 18-carbon fatty acids. | 2012 | Chem. Senses | pmid:22459162 |
| Ménard N et al. | Novel surfactants with diglutamic acid polar head group: drug solubilization and toxicity studies. | 2012 | Pharm. Res. | pmid:22451248 |
| Ruiz M et al. | A cardiac-specific robotized cellular assay identified families of human ligands as inducers of PGC-1α expression and mitochondrial biogenesis. | 2012 | PLoS ONE | pmid:23056435 |
| Saei-Dehkordi SS et al. | Chemical composition and antioxidative activity of Echinophora platyloba DC. essential oil, and its interaction with natural antimicrobials against food-borne pathogens and spoilage organisms. | 2012 | J. Food Sci. | pmid:23106123 |
| Garcia CV et al. | Characterisation of bound volatile compounds of a low flavour kiwifruit species: Actinidia eriantha. | 2012 | Food Chem | pmid:23107675 |
| Smith AN et al. | Unsaturated fatty acids induce mesenchymal stem cells to increase secretion of angiogenic mediators. | 2012 | J. Cell. Physiol. | pmid:22105830 |
| Sauerwald UC et al. | Effect of different levels of docosahexaenoic acid supply on fatty acid status and linoleic and α-linolenic acid conversion in preterm infants. | 2012 | J. Pediatr. Gastroenterol. Nutr. | pmid:22008957 |
| Martorell P et al. | Caenorhabditis elegans as a model to study the effectiveness and metabolic targets of dietary supplements used for obesity treatment: the specific case of a conjugated linoleic acid mixture (Tonalin). | 2012 | J. Agric. Food Chem. | pmid:23072574 |
| Hu ZP et al. | Metabonomic profiling of TASTPM transgenic Alzheimer's disease mouse model. | 2012 | J. Proteome Res. | pmid:23078235 |
| Heinze VM and Actis AB | Dietary conjugated linoleic acid and long-chain n-3 fatty acids in mammary and prostate cancer protection: a review. | 2012 | Int J Food Sci Nutr | pmid:21762028 |
| Celia C et al. | Ethosomes® and transfersomes® containing linoleic acid: physicochemical and technological features of topical drug delivery carriers for the potential treatment of melasma disorders. | 2012 | Biomed Microdevices | pmid:21960035 |
| Buchhaupt M et al. | Synthesis of green note aroma compounds by biotransformation of fatty acids using yeast cells coexpressing lipoxygenase and hydroperoxide lyase. | 2012 | Appl. Microbiol. Biotechnol. | pmid:21789493 |
| Yumrutas O et al. | Phenolic acid contents, essential oil compositions and antioxidant activities of two varieties of Salvia euphratica from Turkey. | 2012 | Nat. Prod. Res. | pmid:21995274 |
| Tyagi A et al. | Attenuation of colonic inflammation by partial replacement of dietary linoleic acid with α-linolenic acid in a rat model of inflammatory bowel disease. | 2012 | Br. J. Nutr. | pmid:22243775 |
| Zhou H et al. | Purification and characterization of a novel ~18 kDa antioxidant protein from Ginkgo biloba seeds. | 2012 | Molecules | pmid:23519252 |
| Kurotani K et al. | High levels of stearic acid, palmitoleic acid, and dihomo-γ-linolenic acid and low levels of linoleic acid in serum cholesterol ester are associated with high insulin resistance. | 2012 | Nutr Res | pmid:23084639 |
| Trevizan L et al. | Maintenance of arachidonic acid and evidence of Δ5 desaturation in cats fed γ-linolenic and linoleic acid enriched diets. | 2012 | Lipids | pmid:22249937 |
| Zhu X et al. | Release property and antioxidant effectiveness of tocopherol-incorporated LDPE/PP blend films. | 2012 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:22257167 |
| Tanaka R et al. | Prenylated acylphloroglucinol derivatives: isoprenomics-based design, syntheses and antioxidative activities. | 2012 | Adv. Exp. Med. Biol. | pmid:22259110 |
| Raatz SK et al. | Total dietary fat and fatty acid content modifies plasma phospholipid fatty acids, desaturase activity indices, and urinary prostaglandin E in women. | 2012 | Nutr Res | pmid:22260857 |
| Regensburger J et al. | Fatty acids and vitamins generate singlet oxygen under UVB irradiation. | 2012 | Exp. Dermatol. | pmid:22229443 |
| Mormile R et al. | Linoleic acid and colorectal cancer cell growth suppression: is the deregulation of mitochondrial survivin the key factor? | 2012 | Int J Colorectal Dis | pmid:22231621 |
| Ramos Morales E et al. | Ricinoleic acid inhibits methanogenesis and fatty acid biohydrogenation in ruminal digesta from sheep and in bacterial cultures. | 2012 | J. Anim. Sci. | pmid:22829608 |
| Luévano-MartÃnez LA et al. | A critical tyrosine residue determines the uncoupling protein-like activity of the yeast mitochondrial oxaloacetate carrier. | 2012 | Biochem. J. | pmid:22236206 |
| Jorge AT et al. | Schinus terebinthifolius Raddi extract and linoleic acid from Passiflora edulis synergistically decrease melanin synthesis in B16 cells and reconstituted epidermis. | 2012 | Int J Cosmet Sci | pmid:22738140 |
| Manzoor M et al. | Variation in minerals, phenolics and antioxidant activity of peel and pulp of different varieties of peach (Prunus persica L.) fruit from Pakistan. | 2012 | Molecules | pmid:22728349 |
| Tao XM et al. | Enhanced anticancer activity of gemcitabine coupling with conjugated linoleic acid against human breast cancer in vitro and in vivo. | 2012 | Eur J Pharm Biopharm | pmid:22728546 |
| Shen J et al. | Effect of essential fatty acids on glucose-induced cytotoxicity to retinal vascular endothelial cells. | 2012 | Lipids Health Dis | pmid:22781401 |
| Al-Said MS et al. | Edible oils for liver protection: hepatoprotective potentiality of Moringa oleifera seed oil against chemical-induced hepatitis in rats. | 2012 | J. Food Sci. | pmid:22757719 |
| Amoo SO et al. | Antioxidant and acetylcholinesterase-inhibitory properties of long-term stored medicinal plants. | 2012 | BMC Complement Altern Med | pmid:22769046 |
| Park EY et al. | Effects of peptide fractions with different isoelectric points from wheat gluten hydrolysates on lipid oxidation in pork meat patties. | 2012 | J. Agric. Food Chem. | pmid:22747172 |
| Pestana JM et al. | Effect of slaughter season and muscle type on the fatty acid composition, including conjugated linoleic acid isomers, and nutritional value of intramuscular fat in organic beef. | 2012 | J. Sci. Food Agric. | pmid:22473659 |
| Kowalska A et al. | Impact of diets with different proportions of linseed and sunflower oils on the growth, liver histology, immunological and chemical blood parameters, and proximate composition of pikeperch Sander lucioperca (L.). | 2012 | Fish Physiol. Biochem. | pmid:21656178 |
| MartÃnez MarÃn AL et al. | Effects of feeding increasing dietary levels of high oleic or regular sunflower or linseed oil on fatty acid profile of goat milk. | 2012 | J. Dairy Sci. | pmid:22459841 |
| Maqbool A et al. | Relation between dietary fat intake type and serum fatty acid status in children with cystic fibrosis. | 2012 | J. Pediatr. Gastroenterol. Nutr. | pmid:22699835 |
| da Silva Acosta D et al. | Fullerene and omega-3 and omega-6 fatty acids on fish brain antioxidant status. | 2012 | Fish Physiol. Biochem. | pmid:22451341 |
| Tanigai T et al. | Docosahexaenoic acid exerts anti-inflammatory action on human eosinophils through peroxisome proliferator-activated receptor-independent mechanisms. | 2012 | Int. Arch. Allergy Immunol. | pmid:22487606 |
| Romano R et al. | Comparison of the frying performance of olive oil and palm superolein. | 2012 | J. Food Sci. | pmid:22490166 |
| Cerretani L et al. | DSC evaluation of extra virgin olive oil stability under accelerated oxidative test: effect of fatty acid composition and phenol contents. | 2012 | J Oleo Sci | pmid:22687775 |
| Hill S et al. | Small amounts of isotope-reinforced polyunsaturated fatty acids suppress lipid autoxidation. | 2012 | Free Radic. Biol. Med. | pmid:22705367 |
| de Freitas JM et al. | Influence of cellular fatty acid composition on the response of Saccharomyces cerevisiae to hydrostatic pressure stress. | 2012 | FEMS Yeast Res. | pmid:22846157 |
| Kamitani S et al. | Differences between group X and group V secretory phospholipase A(2) in lipolytic modification of lipoproteins. | 2012 | Cell. Mol. Biol. Lett. | pmid:22706677 |
| Roongpisuthipong W et al. | Essential fatty acid deficiency while a patient receiving fat regimen total parenteral nutrition. | 2012 | BMJ Case Rep | pmid:22707694 |
| de Sousa Ferreira Soares G et al. | Spectroscopic and thermooxidative analysis of organic okra oil and seeds from Abelmoschus esculentus. | 2012 | ScientificWorldJournal | pmid:22645459 |
| Wiebe MG et al. | Lipid production in batch and fed-batch cultures of Rhodosporidium toruloides from 5 and 6 carbon carbohydrates. | 2012 | BMC Biotechnol. | pmid:22646156 |
| Itakura H et al. | The change in low-density lipoprotein cholesterol concentration is positively related to plasma docosahexaenoic acid but not eicosapentaenoic acid. | 2012 | J. Atheroscler. Thromb. | pmid:22653220 |
| Wakabayashi K et al. | Species differences in toxicokinetic parameters of glycidol after a single dose of glycidol or glycidol linoleate in rats and monkeys. | 2012 | J Toxicol Sci | pmid:22863850 |
| Lasa A et al. | The combination of resveratrol and CLA does not increase the delipidating effect of each molecule in 3T3-L1 adipocytes. | 2011 Sep-Oct | Nutr Hosp | pmid:22072344 |