Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Kharasch ED and Novak RF | Mitoxantrone and ametantrone inhibit hydroperoxide-dependent initiation and propagation reactions in fatty acid peroxidation. | 1985 | J. Biol. Chem. | pmid:2993283 |
Charnock JS et al. | Changes in fatty acid composition of the cardiac phospholipids of the cotton-eared marmoset (Callithrix jacchus) after feeding different lipid supplements. | 1985 | Ann. Nutr. Metab. | pmid:3922279 |
Hansen HS and Jensen B | Essential function of linoleic acid esterified in acylglucosylceramide and acylceramide in maintaining the epidermal water permeability barrier. Evidence from feeding studies with oleate, linoleate, arachidonate, columbinate and alpha-linolenate. | 1985 | Biochim. Biophys. Acta | pmid:3922424 |
Nugteren DH et al. | Metabolism of linoleic acid and other essential fatty acids in the epidermis of the rat. | 1985 | Biochim. Biophys. Acta | pmid:3922425 |
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Roshanai F and Sanders TA | Influence of different supplements of N-3 polyunsaturated fatty acids on blood and tissue lipids in rats receiving high intakes of linoleic acid. | 1985 | Ann. Nutr. Metab. | pmid:4037727 |
Charnock JS et al. | Altered levels of n-6/n-3 fatty acids in rat heart and storage fat following variable dietary intake of linoleic acid. | 1985 | Ann. Nutr. Metab. | pmid:4051450 |
Charnock JS et al. | Diet and cardiac arrhythmia: effects of lipids on age-related changes in myocardial function in the rat. | 1985 | Ann. Nutr. Metab. | pmid:4051452 |
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Pascaud M and Strouve-Vallet C | Desaturation of 14C linoleic acid by the rat fetus. | 1985 | Ann. Nutr. Metab. | pmid:2983600 |
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Boberg M et al. | Platelet fatty acid composition in relation to fatty acid composition in plasma and to serum lipoprotein lipids in healthy subjects with special reference to the linoleic acid pathway. | 1985 | Clin. Sci. | pmid:3919990 |
Erskine KJ et al. | An altered ratio of 18:2 (9,11) to 18:2 (9,12) linoleic acid in plasma phospholipids as a possible predictor of pre-eclampsia. | 1985 | Lancet | pmid:2857904 |
Salzmann-Reinhardt U et al. | Metabolism of polyunsaturated fatty acids by rabbit reticulocytes. | 1985 | Eur. J. Biochem. | pmid:3933978 |