Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Nestel PJ et al. | Effect of a stearic acid-rich, structured triacylglycerol on plasma lipid concentrations. | 1998 | Am. J. Clin. Nutr. | pmid:9846846 |
Oyama Y et al. | Protective actions of 5'-n-alkylated curcumins on living cells suffering from oxidative stress. | 1998 | Eur. J. Pharmacol. | pmid:9845274 |
Turpeinen AM et al. | A high linoleic acid diet increases oxidative stress in vivo and affects nitric oxide metabolism in humans. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9844997 |
Phifer CB and Berthoud HR | Duodenal nutrient infusions differentially affect sham feeding and Fos expression in rat brain stem. | 1998 | Am. J. Physiol. | pmid:9841547 |
Iwase H et al. | Calcium is required for quasi-lipoxygenase activity of hemoproteins. | 1998 | Free Radic. Biol. Med. | pmid:9840740 |
Gu JY et al. | Effect of dietary fats and sesamin on the lipid metabolism and immune function of Sprague-Dawley rats. | 1998 | Biosci. Biotechnol. Biochem. | pmid:9836427 |
Morita Y et al. | Involvement of lipid peroxidation in free fatty acid-induced isolated rat pancreatic acinar cell injury. | 1998 | Pancreas | pmid:9821180 |
Broun P et al. | Catalytic plasticity of fatty acid modification enzymes underlying chemical diversity of plant lipids. | 1998 | Science | pmid:9812895 |
Masia A et al. | Enrichment with a polyunsaturated fatty acid enhances the survival of Saccharomyces cerevisiae in the presence of tributyltin. | 1998 | FEMS Microbiol. Lett. | pmid:9809434 |
Cunnane SC et al. | Substantial carbon recycling from linoleate into products of de novo lipogenesis occurs in rat liver even under conditions of extreme dietary linoleate deficiency. | 1998 | J. Lipid Res. | pmid:9799813 |