Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Park JY et al. | Role of hyperpolarization attained by linoleic acid in chick myoblast fusion. | 1999 | Exp. Cell Res. | pmid:10471316 |
Meek S et al. | Microcystin affinity purification of plant protein phosphatases: PP1C, PP5 and a regulatory A-subunit of PP2A. | 1999 | FEBS Lett. | pmid:10471836 |
Chamruspollert M and Sell JL | Transfer of dietary conjugated linoleic acid to egg yolks of chickens. | 1999 | Poult. Sci. | pmid:10472840 |
Lin MY and Yen CL | Reactive oxygen species and lipid peroxidation product-scavenging ability of yogurt organisms. | 1999 | J. Dairy Sci. | pmid:10480088 |
Kankaanpää P et al. | Dietary fatty acids and allergy. | 1999 | Ann. Med. | pmid:10480759 |
Precht D and Molkentin J | C18:1, C18:2 and C18:3 trans and cis fatty acid isomers including conjugated cis delta 9, trans delta 11 linoleic acid (CLA) as well as total fat composition of German human milk lipids. | 1999 | Nahrung | pmid:10481820 |
Sauer LA et al. | 13-Hydroxyoctadecadienoic acid is the mitogenic signal for linoleic acid-dependent growth in rat hepatoma 7288CTC in vivo. | 1999 | Cancer Res. | pmid:10493526 |
Blask DE et al. | Melatonin inhibition of cancer growth in vivo involves suppression of tumor fatty acid metabolism via melatonin receptor-mediated signal transduction events. | 1999 | Cancer Res. | pmid:10493527 |
Rickert KW and Klinman JP | Nature of hydrogen transfer in soybean lipoxygenase 1: separation of primary and secondary isotope effects. | 1999 | Biochemistry | pmid:10493789 |
Tamatani T et al. | Neoplastic conversion of human urothelial cells in vitro by overexpression of H2O2-generating peroxisomal fatty acyl CoA oxidase. | 1999 | Int. J. Oncol. | pmid:10493957 |