Linoleic acid

Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.

Cross Reference

Introduction

To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoleic acid?

Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoleic acid

MeSH term MeSH ID Detail
Genetic Diseases, X-Linked D040181 2 associated lipids
Lactose Intolerance D007787 2 associated lipids
Circoviridae Infections D018173 2 associated lipids
Spirochaetales Infections D013145 2 associated lipids
Lymphopenia D008231 2 associated lipids
Pneumonia, Viral D011024 3 associated lipids
Pregnancy Complications, Neoplastic D011252 4 associated lipids
Melanosis D008548 4 associated lipids
Exocrine Pancreatic Insufficiency D010188 6 associated lipids
Otitis Externa D010032 8 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Anorexia D000855 8 associated lipids
Constipation D003248 8 associated lipids
Hypertension, Renal D006977 9 associated lipids
Hyperlipidemia, Familial Combined D006950 9 associated lipids
Renal Insufficiency, Chronic D051436 9 associated lipids
Staphylococcal Skin Infections D013207 9 associated lipids
Coronary Restenosis D023903 10 associated lipids
Hyperpigmentation D017495 11 associated lipids
Acute Coronary Syndrome D054058 11 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoleic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with Linoleic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoleic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoleic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoleic acid

Download all related citations
Per page 10 20 50 100 | Total 4513
Authors Title Published Journal PubMed Link
NESTEL PJ METABOLISM OF LINOLEATE AND PALMITATE IN PATIENTS WITH HYPERTRIGLYCERIDEMIA AND HEART DISEASE. 1965 Metab. Clin. Exp. pmid:14252339
CHRISTAKIS GJ et al. EFFECT OF A SERUM CHOLESTEROL-LOWERING DIET ON COMPOSITION OF DEPOT FAT IN MAN. 1965 Am. J. Clin. Nutr. pmid:14253897
ZUKEL MC FAT-CONTROLLED DIETS. 1965 Am. J. Clin. Nutr. pmid:14253901
MARION JE EFFECT OF AGE AND DIETARY FAT ON THE LIPIDS OF CHICKEN MUSCLE. 1965 J. Nutr. pmid:14257000
PRIVETT OS et al. INFLUENCE OF DIETARY FAT ON TRIGLYCERIDE STRUCTURE IN THE RAT. 1965 J. Nutr. pmid:14259460
YAMAMOTO A et al. INFLUENCE OF DIETARY FATTY ACIDS ON PHOSPHOLIPID FATTY ACID COMPOSITION IN SUBCELLULAR PARTICLES OF RAT LIVER. 1965 J. Lipid Res. pmid:14330770
CAMPBELL AM et al. SERUM LIPIDS OF MEN FED DIETS DIFFERING IN PROTEIN QUALITY AND LINOLEIC ACID CONTENT. 1965 Am. J. Clin. Nutr. pmid:14332349
KOKATNUR MG et al. A RAPID METHOD FOR THE PREPARATION OF PEROXIDES FROM AUTOXIDIZED METHYL ESTERS OF FATTY ACIDS. 1965 Anal. Biochem. pmid:14340025
SGOUTAS D et al. RADIOHOMOGENEITY OF H3- AND C14-LABELED LINOLEIC ACID IN VIVO. 1965 J. Lipid Res. pmid:14343270
HARRIS RV and JAMES AT CONVERSION OF OLEIC ACID INTO LINOLEIC ACID BY A SUBCELLULAR SYSTEM OF CHLORELLA VULGARIS. 1965 Biochem. J. pmid:14346083
ALLMANN DW and GIBSON DM FATTY ACID SYNTHESIS DURING EARLY LINOLEIC ACID DEFICIENCY IN THE MOUSE. 1965 J. Lipid Res. pmid:14280473
ALLMANN DW et al. FATTY ACID SYNTHESIS DURING FAT-FREE REFEEDING OF STARVED RATS. 1965 J. Lipid Res. pmid:14280474
SHAW R THE OCCURRENCE OF GAMMA-LINOLENIC ACID IN FUNGI. 1965 Biochim. Biophys. Acta pmid:14320219
WILLS ED MECHANISMS OF LIPID PEROXIDE FORMATION IN TISSUES. ROLE OF METALS AND HAEMATIN PROTEINS IN THE CATALYSIS OF THE OXIDATION UNSATURATED FATTY ACIDS. 1965 Biochim. Biophys. Acta pmid:14325327
MEGHAL SK and NATH MC ACTION OF FATS AND LINOLEIC ACID ON INTESTINAL SYNTHESIS OF THIAMINE IN THIAMINE-DEFICIENT RATS. 1965 Br. J. Nutr. pmid:14290858
DANIEL JC STUDIES ON THE GROWTH OF 5-DAY-OLD RABBIT BLASTOCYSTS IN VITRO. 1965 J Embryol Exp Morphol pmid:14296279
GLENN JL and DAM H INFLUENCE OF DIETARY LIPIDS ON THE FATTY ACID COMPOSITION OF NEUTRAL LIPIDS AND PHOSPHATIDES IN CHICK LIVER AND BILE. 1965 J. Nutr. pmid:14300993
KRAUSE RF LIVER LIPIDS IN A CASE OF HYPERVITAMINOSIS A. 1965 Am. J. Clin. Nutr. pmid:14301352
JAMES AT et al. THE BIOSYNTHESIS OF RICINOLEIC ACID. 1965 Biochem. J. pmid:14340094
SCHWARTZ S et al. LIPID THROMBOPLASTINS AND MYOCARDIAL INFARCTION. 1965 Am. J. Med. Sci. pmid:14254823
SINGLETON WS CHARACTERIZED OILS FOR USE IN INTRAVENOUS FAT EMULSIONS. 1965 Am. J. Clin. Nutr. pmid:14262113
MORIN RJ EFFECTS OF 4-DIMETHYLAMINOAZOBENZENE ON HEPATIC MICROSOMAL PHOSPHOLIPIDS. 1965 Cancer Res. pmid:14264043
STEIN AA et al. FATTY ACID ANALYSIS OF TWO EXPERIMENTAL TRANSMISSIBLE GLIAL TUMORS BY GAS-LIQUID CHROMATOGRAPHY. 1965 Cancer Res. pmid:14264052
BAKER RW et al. SERUM CHOLESTEROL LINOLEATE LEVELS IN MULTIPLE SCLEROSIS. 1965 J. Neurol. Neurosurg. Psychiatr. pmid:14347622
ANSTALL HB and TRUJILLO JM DETERMINATION OF FREE FATTY ACIDS IN PLASMA BY A COLORIMETRIC PROCEDURE: AN APPRAISAL OF THE METHOD AND COMPARISON WITH OTHER TECHNICS. 1965 Clin. Chem. pmid:14319230
GLENDE EA and CORNATZER WE FATTY ACID COMPOSITION OF RAT LIVER LIPIDS DURING CHOLINE DEFICIENCY. 1965 J. Nutr. pmid:14302120
HOLMES FE AIR-COOLED EXTRACTORS AND THEIR USE IN DETERMINATION OF CHOLESTEROL. 1965 Clin. Chem. pmid:14243897
Kabara JJ et al. Fatty acids and derivatives as antimicrobial agents. 1972 Antimicrob. Agents Chemother. pmid:4670656
Kohn A et al. Interaction of polyunsaturated fatty acids with animal cells and enveloped viruses. 1980 Antimicrob. Agents Chemother. pmid:7235682
Volpe JJ and Obert KA Coordinate regulation of cholesterol synthesis and 3-hydroxy-3-methylglutaryl coenzyme A synthase but not 3-hydroxy-3-methylglutaryl coenzyme A reductase in C-6 glia. 1981 Arch. Biochem. Biophys. pmid:6118099
Lewis MG et al. Effect of essential polyunsaturated fatty acid modifications on prostaglandin production by MDCK canine kidney cells. 1981 Prostaglandins pmid:6799988
Gavigan SJ and Knight BL Catabolism of low-density lipoprotein by fibroblasts cultured in medium supplemented with saturated or unsaturated free fatty acids. 1981 Biochim. Biophys. Acta pmid:6271233
Cheah AM Effect of long chain unsaturated fatty acids on the calcium transport of sarcoplasmic reticulum. 1981 Biochim. Biophys. Acta pmid:6118177
Liffmann SM and Lynch RD Incorporation of [3H]acetate into L-cell lipids. Dependence on method of linoleate administration and timing of the pulse label. 1981 Biochim. Biophys. Acta pmid:7295748
Dwyer LA and Blomquist GJ Biosynthesis of linoleic acid in the American cockroach. 1981 Prog. Lipid Res. pmid:7342085
Launay M et al. Control of replication by dietary lipids and namely by linoleic acid in liver and adipose tissue of developing rats. 1981 Prog. Lipid Res. pmid:7342098
Houtsmuller AJ et al. Favorable influences of linoleic acid on the progression of diabetic micro- and macroangiopathy in adult onset diabetes mellitus. 1981 Prog. Lipid Res. pmid:7342100
Kitada S et al. Characterization of a lipid mobilizing factor from tumors. 1981 Prog. Lipid Res. pmid:7342133
Spector AA et al. Utilization of arachidonic and linoleic acids by cultured human endothelial cells. 1981 J. Clin. Invest. pmid:6793627
Kinsella JE et al. Metabolism of trans fatty acids with emphasis on the effects of trans, trans-octadecadienoate on lipid composition, essential fatty acid, and prostaglandins: an overview. 1981 Am. J. Clin. Nutr. pmid:6794350
Andersen BR et al. The effects of arachidonic and other fatty acids on canine neutrophil metabolism. 1981 Prostaglandins pmid:6795686
McDaniel HG et al. Glucose-insulin-potassium induced alterations in individual plasma free fatty acids in patients with acute myocardial infarction. 1981 Am. Heart J. pmid:6787909
Naidoo J Effect of pH on inhibition of plasmid-carrying cultures of Staphylococcus aureus by lipids. 1981 J. Gen. Microbiol. pmid:7320698
Christophersen BO and Norseth J Arachidonic acid synthesis in isolated liver cells:" effects of (-)-carnitine and of (+)-decanoylcarnitine. 1981 FEBS Lett. pmid:6796433
Cunnane SC Diodoquin and linoleic acid absorption in zinc deficiency. 1981 Am. J. Clin. Nutr. pmid:6792900
Schieberle P et al. A study of oxygen isotope scrambling in the enzymic and non-enzymic oxidation of linoleic acid. 1981 Biochim. Biophys. Acta pmid:6798993
Spector AA et al. Essential fatty acid availability and prostacyclin production by cultured human endothelial cells. 1981 Prog. Lipid Res. pmid:7043481
Agradi E et al. Dietary linoleic acid, accumulation of arachidonic acid in tissue lipids and production of TXB2 and PGI2 in the cardiovascular system. 1981 Prog. Lipid Res. pmid:7043483
Mercuri O and De Tomás ME Early steps on the in vivo incorporation of [1-14C]linoleic acid into liver lipids of protein deficient pregnant rats. 1981 Prog. Lipid Res. pmid:6804968
Kuriki Y Effects of unsaturated fatty acids on the morphogenesis of an unsaturated fatty acid auxotroph of Escherichia coli. 1981 J. Bacteriol. pmid:7024246