| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Alopecia | D000505 | 14 associated lipids |
| Anorexia | D000855 | 8 associated lipids |
| Olfaction Disorders | D000857 | 17 associated lipids |
| Aortic Diseases | D001018 | 11 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Birth Weight | D001724 | 23 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Constipation | D003248 | 8 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Heart Defects, Congenital | D006330 | 20 associated lipids |
Linoleic acid
Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoleic acid?
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoleic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with Linoleic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoleic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoleic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoleic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| REID ME et al. | NUTRITIONAL STUDIES WITH THE GUINEA PIG. X. DETERMINATION OF THE LINOLEIC ACID REQUIREMENT. | 1964 | J. Nutr. | pmid:14151124 |
| MOORE JH and WILLIAMS DL | THE EFFECT OF DIET ON THE LEVEL OF PLASMA CHOLESTEROL AND THE DEGREE OF ATHEROMATOUS DEGENERATION IN THE RABBIT. | 1964 | Br. J. Nutr. | pmid:14154252 |
| CENTURY B and HORWITT MK | ROLE OF ARACHIDONIC ACID IN NUTRITIONAL ENCEPHALOMALACIA: INTERRELATIONSHIP OF ESSENTIAL AND NONESSENTIAL POLYUNSATURATED FATTY ACIDS. | 1964 | Arch. Biochem. Biophys. | pmid:14161009 |
| BRESSLER R and FRIEDBERG SJ | SUBSTRATE SPECIFICITY OF THE FATTY ACID OXIDASE IN THE HEART. | 1964 | Arch. Biochem. Biophys. | pmid:14161011 |
| ARFFMANN E | HEATED FATS AND ALLIED COMPOUNDS AS CARCINOGENS; STUDIED BY THE NEWT TEST. | 1964 | Acta Pathol Microbiol Scand | pmid:14162795 |
| WALKER BL and KUMMEROW FA | DIETARY FAT AND THE STRUCTURE AND PROPERTIES OF RAT ERYTHROCYTES. III. RESPONSE OF ERYTHROCYTE FATTY ACIDS TO VARIOUS DIETARY FATS. | 1964 | J. Nutr. | pmid:14133362 |
| HOLMAN RT et al. | ESTIMATION OF LINOLEATE INTAKE OF MEN FROM SERUM LIPID ANALYSIS. | 1964 | Am. J. Clin. Nutr. | pmid:14142377 |
| VAHOUNY GV et al. | MICELLAR-SOLUBILIZED SUBSTRATES AND CHOLESTEROL ESTERASE ACTIVITY IN VITRO. | 1964 | Arch. Biochem. Biophys. | pmid:14211570 |
| PORTMAN OW and SUGANO M | FACTORS INFLUENCING THE LEVEL AND FATTY ACID SPECIFICITY OF THE CHOLESTEROL ESTERIFICATION ACTIVITY IN HUMAN PLASMA. | 1964 | Arch. Biochem. Biophys. | pmid:14236639 |
| JACKSON HD et al. | FORMATION OF KETONE BODIES FROM LONG-CHAIN FATTY ACIDS IN RUMEN EPITHELIUM AND LIVER FROM KETOTIC SHEEP. | 1964 | Arch. Biochem. Biophys. | pmid:14240563 |
| MOORE JH and WILLIAMS D | THE RELATIONSHIP BETWEEN THE LINOLEIC ACID CONTENT OF THE DIET, THE FATTY ACID COMPOSITION OF THE PLASMA PHOSPHOLIPIDS AND THE DEGREE OF AORTIC ATHEROSIS IN EXPERIMENTAL RABBITS. | 1964 | Br. J. Nutr. | pmid:14241591 |
| ZUCKERMAN AJ and MACDONAID L | THE ROLE OF DIETARY CARBOHYDRATES AND INFECTION ON LIVER LIPID AND COLLAGEN. | 1964 | Br J Exp Pathol | pmid:14245158 |
| SWELL L et al. | ROLE OF THE LIVER IN THE METABOLISM OF EXOGENOUS CHOLESTEROL ESTERS. | 1964 | Arch. Biochem. Biophys. | pmid:14236640 |
| ENGELMANN D et al. | [CONCERNING THE RESORPTION AND METABOLISM OF SOME 1-14C-LABELLED FREE FATTY ACIDS IN YOUNG RABBITS]. | 1964 | Clin. Chim. Acta | pmid:14122499 |
| MAHADEVAN S et al. | STUDIES ON METABOLISM OF VITAMIN A. 3. THE MODE OF ABSORPTION OF VITAMIN A ESTERS IN THE LIVING RAT. | 1963 | Biochem. J. | pmid:14071526 |
| MAHADEVAN S et al. | STUDIES ON METABOLISM OF VITAMIN A. 4. STUDIES ON THE MODE OF ABSORPTION OF VITAMIN A BY RAT INTESTINE IN VITRO. | 1963 | Biochem. J. | pmid:14071527 |
| STEIN O and STEIN Y | METABOLISM OF FATTY ACIDS IN THE ISOLATED PERFUSED RAT HEART. | 1963 | Biochim. Biophys. Acta | pmid:14085937 |
| LEAT WM | FATTY ACID COMPOSITION OF THE SERUM LIPIDS OF PIGS GIVEN DIFFERENT AMOUNTS OF LINOLEIC ACID. | 1963 | Biochem. J. | pmid:14097364 |
| YOUNG RJ and GARRETT RL | EFFECT OF OLEIC AND LINOLEIC ACIDS ON THE ABSORPTION OF SATURATED FATTY ACIDS IN THE CHICK. | 1963 | J. Nutr. | pmid:14100991 |
| JOHNSON RC and GARY ND | NUTRITION OF LEPTOSPIRA POMONA. II. FATTY ACID REQUIREMENTS. | 1963 | J. Bacteriol. | pmid:14044026 |
| BENNETT JR | THE ESTERIFICATION OF CHOLESTEROL BY RAT-LIVER PREPARATIONS. | 1963 | Biochim. Biophys. Acta | pmid:14067620 |
| HAYASHIDA T and PORTMAN OW | CHANGES IN SUCCINIC DEHYDROGENASE ACTIVITY AND FATTY ACID COMPOSITION OF RAT LIVER MITOCHONDRIA IN ESSENTIAL FATTY ACID DEFICIENCY. | 1963 | J. Nutr. | pmid:14068923 |
| PELUFFO RO et al. | ACTION OF LINOLEIC AND ARACHIDONIC ACIDS UPON THE EICOSATRIENOIC ACID LEVEL IN RAT HEART AND LIVER. | 1963 | J. Nutr. | pmid:14068924 |
| PORTMAN OW and SUGANO M | THE HYDROLYSIS AND FATTY ACID EXCHANGE OF CHOLESTEROL ESTERS ADMINISTERED IN LIPOPROTEINS TO CEBUS MONKEYS. | 1963 | Arch. Biochem. Biophys. | pmid:14072510 |
| MATSUSHITA S et al. | CHEMICAL REACTIVITY OF THE NUCLEIC ACID BASES. I. ANTIOXIDATIVE ABILITY OF THE NUCLEIC ACIDS AND THEIR RELATED SUBSTANCES ON THE OXIDATION OF UNSATURATED FATTY ACIDS. | 1963 | Arch. Biochem. Biophys. | pmid:14072524 |
| HUGHES G et al. | LINOLEIC ACID--AN ESSENTIAL NUTRIENT: ITS CONTENT IN INFANT FORMULAS AND PRECOOKED CEREALS. | 1963 | Clin Pediatr (Phila) | pmid:14072730 |
| SWELL L et al. | DYNAMIC ASPECTS OF CHOLESTEROL ESTER METABOLISM IN RABBITS WITH ATHEROSCLEROSIS. | 1963 | J. Nutr. | pmid:14083242 |
| ERWIN ES and STERNER W | DIETARY LIPIDS AND FATTY ACID DEPOSITION IN VARIOUS CALF TISSUES. | 1963 | Am. J. Physiol. | pmid:14084975 |
| KAI M et al. | FATTY ACID COMPOSITION OF LECITHIN FROM BEEF BRAIN AND EGG YOLK. | 1963 | J. Biochem. | pmid:14089733 |
| LEVEILLE GA et al. | FATTY ACID COMPOSITION OF PLASMA AND LIVER LIPID COMPONENTS AS INFLUENCED BY DIET IN THE GROWING CHICK. | 1963 | J. Nutr. | pmid:14100995 |
| CENTURY B et al. | INTERRELATIONSHIPS OF DIETARY LIPIDS UPON FATTY ACID COMPOSITION OF BRAIN MITOCHONDRIA, ERYTHROCYTES AND HEART TISSUE IN CHICKS. | 1963 | Am. J. Clin. Nutr. | pmid:14101397 |
| LESSELL S and KUWABARA T | LINOLEIC ACID IN INFANT NUTRITION. | 1963 | Br Med J | pmid:14057706 |
| MORRIS B and SIMPSON-MORGAN MW | THE OXIDATION OF CONTINUOUSLY INFUSED CHYLOMICRON FATTY ACIDS BY UNANESTHETIZED RATS. | 1963 | J. Physiol. (Lond.) | pmid:14103556 |
| WAYS P et al. | RED-CELL AND PLASMA LIPIDS IN ACANTHOCYTOSIS. | 1963 | J. Clin. Invest. | pmid:14060400 |
| MOHRHAUER H and HOLMAN RT | EFFECT OF LINOLENIC ACID UPON THE METABOLISM OF LINOLEIC ACID. | 1963 | J. Nutr. | pmid:14061405 |
| IMAI H | STUDY BY ELECTRON MICROSCOPY OF OLEIC AND LINOLEIC ACIDS INJECTED INTRABRONCHIALLY INTO THE LUNGS OF RATS. | 1963 | Exp. Mol. Pathol. | pmid:14061852 |
| JAMESON E et al. | PROTECTION BY DIETARY FAT AFFORDED SERUM GAMMA 1-GLOBULIN OF X-IRRADIATED RATS. | 1963 | J. Nutr. | pmid:14062658 |
| WATSON WC | The morphology and lipid composition of the erythrocytes in normal and essential-fatty-acid-deficient rats. | 1963 | Br. J. Haematol. | pmid:13999227 |
| WOOD RD et al. | Metabolism of labeled linoleic-1-C-14 acid in the sheep rumen. | 1963 | J. Nutr. | pmid:14001756 |
| STEIN Y et al. | Enzymic pathways of glyceride and phospholipid synthesis in aortic homogenates. | 1963 | Biochim. Biophys. Acta | pmid:13983700 |
| HOMBURGER F et al. | Serum lipid changes accompanying the inclusion of canned fish in the diet. | 1963 | J Am Geriatr Soc | pmid:13961527 |
| BEELER DA and QUACKENBUSH FW | Effect of linoleate and dietary fat level on plasma and liver cholesterol and vascular lesions of the cholesterol-fed rat. | 1963 | J. Nutr. | pmid:13970237 |
| RAZIN S and ROTTEM S | FATTY ACID REQUIREMENTS OF MYCOPLASMA LAIDLAWII. | 1963 | J. Gen. Microbiol. | pmid:14114935 |
| JAGANNATHAN SN | Effect of feeding fat blends of hydrogenated groundnut (peanut) fat and cottonseed oil containing different levels of linoleic acid on serum choles terol levels in monkeys (Macaca radiata) and liver cholesterol concentration in cholesterol-fed rats. | 1962 | J. Nutr. | pmid:14450884 |
| DEYKIN D and GOODMAN DS | The hydrolysis of long-chain fatty acid esters of cholesterol with rat liver enzymes. | 1962 | J. Biol. Chem. | pmid:14027461 |
| SUEYOSHI Y and NAGAO Y | Studies on the linoleic acid contents in the phospholipids of the sarcoma. | 1962 | Keio J Med | pmid:13918168 |
| VIOQUE E and HOLMAN RT | Characterization of the ketodienes formed in the oxidation of linoleate by lipoxidase. | 1962 | Arch. Biochem. Biophys. | pmid:13997422 |
| WILSON JD | Relation between dietary cholesterol and bile acid excretion in the rat. | 1962 | Am. J. Physiol. | pmid:14001040 |
| CASTER WO et al. | Determination of linoleate requirement of swine by a new method of estimating nutritional requirement. | 1962 | J. Nutr. | pmid:14019220 |
| SUEYOSHI Y and NAGAO Y | The influence of linoleic acid upon the growth of transplanted sarcoma. | 1962 | Keio J Med | pmid:13979090 |