Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Medema S et al. | Levels of Red Blood Cell Fatty Acids in Patients With Psychosis, Their Unaffected Siblings, and Healthy Controls. | 2016 | Schizophr Bull | pmid:26385764 |
Valdez-Morales M et al. | Phenolic Compounds, Antioxidant Activity and Lipid Profile of Huitlacoche Mushroom (Ustilago maydis) Produced in Several Maize Genotypes at Different Stages of Development. | 2016 | Plant Foods Hum Nutr | pmid:27605221 |
Zhao Z et al. | The Association of Fatty Acid Levels and Gleason Grade among Men Undergoing Radical Prostatectomy. | 2016 | PLoS ONE | pmid:27880795 |
Yary T et al. | Serum n-6 polyunsaturated fatty acids, Δ5- and Δ6-desaturase activities, and risk of incident type 2 diabetes in men: the Kuopio Ischaemic Heart Disease Risk Factor Study. | 2016 | Am. J. Clin. Nutr. | pmid:27009754 |
Alvarruiz A et al. | Quality and Composition of Virgin Olive Oil from Varietties Grown in Castilla-La Mancha (Spain). | 2015 | J Oleo Sci | pmid:26369595 |
Frenzel E et al. | α1-Antitrypsin Combines with Plasma Fatty Acids and Induces Angiopoietin-like Protein 4 Expression. | 2015 | J. Immunol. | pmid:26363050 |
Xing J et al. | Determining antioxidant activities of lactobacilli cell-free supernatants by cellular antioxidant assay: a comparison with traditional methods. | 2015 | PLoS ONE | pmid:25789875 |
Saccenti E et al. | Strategies for individual phenotyping of linoleic and arachidonic acid metabolism using an oral glucose tolerance test. | 2015 | PLoS ONE | pmid:25786212 |
Yoshida Y et al. | Chemistry of lipid peroxidation products and their use as biomarkers in early detection of diseases. | 2015 | J Oleo Sci | pmid:25766928 |
Miyamoto J et al. | A gut microbial metabolite of linoleic acid, 10-hydroxy-cis-12-octadecenoic acid, ameliorates intestinal epithelial barrier impairment partially via GPR40-MEK-ERK pathway. | 2015 | J. Biol. Chem. | pmid:25505251 |