Linoleic acid

Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.

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Introduction

To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoleic acid?

Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoleic acid

PubChem Associated disorders and diseases

What pathways are associated with Linoleic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with Linoleic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoleic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoleic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoleic acid

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Authors Title Published Journal PubMed Link
Chavali SR and Forse RA Decreased production of interleukin-6 and prostaglandin E2 associated with inhibition of delta-5 desaturation of omega6 fatty acids in mice fed safflower oil diets supplemented with sesamol. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10718106
Baron CP et al. Peroxidation of linoleate at physiological pH: hemichrome formation by substrate binding protects against metmyoglobin activation by hydrogen peroxide. 2000 Free Radic. Biol. Med. pmid:10719236
Fidler N et al. Oxidation of an oil rich in docosahexaenoic acid compared to linoleic acid in lactating women. 1999 Ann. Nutr. Metab. pmid:10725767
Adam O Linoleic acid - the fall of an angel? 1999 Ann. Nutr. Metab. pmid:10725772
Draper AJ and Hammock BD Identification of CYP2C9 as a human liver microsomal linoleic acid epoxygenase. 2000 Arch. Biochem. Biophys. pmid:10729206
Kemp B et al. Influence of linoleic/linolenic acid ratio in the diet of periparturient cattle on plasma concentrations of PGF2 alpha metabolite and placental expulsion rate. 1998 Theriogenology pmid:10732036
Hochi S et al. Effect of linoleic acid-albumin in the culture medium on freezing sensitivity of in vitro-produced bovine morulae. 1999 Theriogenology pmid:10734383
Clemmesen JO et al. Plasma phospholipid fatty acid pattern in severe liver disease. 2000 J. Hepatol. pmid:10735619
Hudson JA et al. Identification and enumeration of oleic acid and linoleic acid hydrating bacteria in the rumen of sheep and cows. 2000 J. Appl. Microbiol. pmid:10735997
Larqué E et al. Dietary trans fatty acids affect the essential fatty-acid concentration of rat milk. 2000 J. Nutr. pmid:10736340