Linoleic acid
Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoleic acid?
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoleic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with Linoleic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoleic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Linoleic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoleic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yildiztekin F et al. | Antioxidant, anticholinesterase and tyrosinase inhibition activities, and fatty acids of Crocus mathewii - A forgotten endemic angiosperm of Turkey. | 2016 | Pharm Biol | pmid:26810584 |
| Ma C et al. | NAFLD causes selective CD4(+) T lymphocyte loss and promotes hepatocarcinogenesis. | 2016 | Nature | pmid:26934227 |
| Padayachee T et al. | The Detection of Metabolite-Mediated Gene Module Co-Expression Using Multivariate Linear Models. | 2016 | PLoS ONE | pmid:26918614 |
| Hellström F et al. | Association between plasma concentrations of linoleic acid-derived oxylipins and the perceived pain scores in an exploratory study in women with chronic neck pain. | 2016 | BMC Musculoskelet Disord | pmid:26916287 |
| Ripoll-Rozada J et al. | Type IV traffic ATPase TrwD as molecular target to inhibit bacterial conjugation. | 2016 | Mol. Microbiol. | pmid:26915347 |
| Harris WS et al. | Red Blood Cell Fatty Acids and Incident Diabetes Mellitus in the Women's Health Initiative Memory Study. | 2016 | PLoS ONE | pmid:26881936 |
| Puebla C et al. | Linoleic acid permeabilizes gastric epithelial cells by increasing connexin 43 levels in the cell membrane via a GPR40- and Akt-dependent mechanism. | 2016 | Biochim. Biophys. Acta | pmid:26869446 |
| Yuan H et al. | A network based covariance test for detecting multivariate eQTL in saccharomyces cerevisiae. | 2016 | BMC Syst Biol | pmid:26818242 |
| Matravadia S et al. | LA and ALA prevent glucose intolerance in obese male rats without reducing reactive lipid content, but cause tissue-specific changes in fatty acid composition. | 2016 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:26764053 |
| Rashed MM et al. | Effect of ultrasonic treatment on total phenolic extraction from Lavandula pubescens and its application in palm olein oil industry. | 2016 | Ultrason Sonochem | pmid:26584982 |
| Moran LJ et al. | Altered Preconception Fatty Acid Intake Is Associated with Improved Pregnancy Rates in Overweight and Obese Women Undertaking in Vitro Fertilisation. | 2016 | Nutrients | pmid:26742065 |
| Iuchi K et al. | Molecular hydrogen regulates gene expression by modifying the free radical chain reaction-dependent generation of oxidized phospholipid mediators. | 2016 | Sci Rep | pmid:26739257 |
| López-Luna P et al. | Fate of orally administered radioactive fatty acids in the late-pregnant rat. | 2016 | Am. J. Physiol. Endocrinol. Metab. | pmid:26714850 |
| Ito J et al. | A novel chiral stationary phase HPLC-MS/MS method to discriminate between enzymatic oxidation and auto-oxidation of phosphatidylcholine. | 2016 | Anal Bioanal Chem | pmid:27549797 |
| Park HG et al. | Palmitic acid (16:0) competes with omega-6 linoleic and omega-3 ɑ-linolenic acids for FADS2 mediated Δ6-desaturation. | 2016 | Biochim. Biophys. Acta | pmid:26597785 |
| Xie P et al. | Metabonomic Study of Biochemical Changes in Human Hair of Heroin Abusers by Liquid Chromatography Coupled with Ion Trap-Time of Flight Mass Spectrometry. | 2016 | J. Mol. Neurosci. | pmid:26445826 |
| DoÄŸru-Koca A et al. | Chemotaxonomic perspectives of the Paracaryum (Cynoglosseae, Boraginaceae) taxa based on fruit fatty acid composition. | 2016 | Phytochemistry | pmid:27600716 |
| Lin HH et al. | Hormonal Modulation of Pheromone Detection Enhances Male Courtship Success. | 2016 | Neuron | pmid:27263969 |
| Troche JR et al. | Alcohol Consumption-Related Metabolites in Relation to Colorectal Cancer and Adenoma: Two Case-Control Studies Using Serum Biomarkers. | 2016 | PLoS ONE | pmid:26967509 |
| Cerf ME and Herrera E | High Fat Diet Administration during Specific Periods of Pregnancy Alters Maternal Fatty Acid Profiles in the Near-Term Rat. | 2016 | Nutrients | pmid:26742067 |
| Sergeant S et al. | Impact of methods used to express levels of circulating fatty acids on the degree and direction of associations with blood lipids in humans. | 2016 | Br. J. Nutr. | pmid:26615716 |
| Valdez-Morales M et al. | Phenolic Compounds, Antioxidant Activity and Lipid Profile of Huitlacoche Mushroom (Ustilago maydis) Produced in Several Maize Genotypes at Different Stages of Development. | 2016 | Plant Foods Hum Nutr | pmid:27605221 |
| Shapiro H et al. | Beyond the classic eicosanoids: Peripherally-acting oxygenated metabolites of polyunsaturated fatty acids mediate pain associated with tissue injury and inflammation. | 2016 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:27067460 |
| Rosenblat M et al. | Nitro-Oleic Acid Reduces J774A.1 Macrophage Oxidative Status and Triglyceride Mass: Involvement of Paraoxonase2 and Triglyceride Metabolizing Enzymes. | 2016 | Lipids | pmid:27344666 |
| Abreu P et al. | Contractile function recovery in severely injured gastrocnemius muscle of rats treated with either oleic or linoleic acid. | 2016 | Exp. Physiol. | pmid:27579497 |
| Zhao Z et al. | The Association of Fatty Acid Levels and Gleason Grade among Men Undergoing Radical Prostatectomy. | 2016 | PLoS ONE | pmid:27880795 |
| Takabe W et al. | Esterification of 24S-OHC induces formation of atypical lipid droplet-like structures, leading to neuronal cell death. | 2016 | J. Lipid Res. | pmid:27647838 |
| Zhang YH et al. | The Use of Gene Ontology Term and KEGG Pathway Enrichment for Analysis of Drug Half-Life. | 2016 | PLoS ONE | pmid:27780226 |
| Rodrigues HG et al. | Oral Administration of Linoleic Acid Induces New Vessel Formation and Improves Skin Wound Healing in Diabetic Rats. | 2016 | PLoS ONE | pmid:27764229 |
| Kojima K et al. | A simple method for isolation and construction of markerless cyanobacterial mutants defective in acyl-acyl carrier protein synthetase. | 2016 | Appl. Microbiol. Biotechnol. | pmid:27704180 |
| Ishida K and Jolly ER | Hsp70 May Be a Molecular Regulator of Schistosome Host Invasion. | 2016 | PLoS Negl Trop Dis | pmid:27611863 |
| Venäläinen TM et al. | Effect of a 2-y dietary and physical activity intervention on plasma fatty acid composition and estimated desaturase and elongase activities in children: the Physical Activity and Nutrition in Children Study. | 2016 | Am. J. Clin. Nutr. | pmid:27581473 |
| Sakayori N et al. | Maternal Nutritional Imbalance between Linoleic Acid and Alpha-Linolenic Acid Increases Offspring's Anxious Behavior with a Sex-Dependent Manner in Mice. | 2016 | Tohoku J. Exp. Med. | pmid:27558477 |
| Karupaiah T et al. | Comparing effects of soybean oil- and palm olein-based mayonnaise consumption on the plasma lipid and lipoprotein profiles in human subjects: a double-blind randomized controlled trial with cross-over design. | 2016 | Lipids Health Dis | pmid:27535127 |
| Raimondi S et al. | Conjugated Linoleic Acid Production by Bifidobacteria: Screening, Kinetic, and Composition. | 2016 | Biomed Res Int | pmid:27429985 |
| Green D et al. | Central activation of TRPV1 and TRPA1 by novel endogenous agonists contributes to mechanical allodynia and thermal hyperalgesia after burn injury. | 2016 | Mol Pain | pmid:27411353 |
| Castrejón-Tellez V et al. | The Effect of Resveratrol and Quercetin Treatment on PPAR Mediated Uncoupling Protein (UCP-) 1, 2, and 3 Expression in Visceral White Adipose Tissue from Metabolic Syndrome Rats. | 2016 | Int J Mol Sci | pmid:27399675 |
| Zhao J et al. | Dietary fat intake and endometrial cancer risk: A dose response meta-analysis. | 2016 | Medicine (Baltimore) | pmid:27399120 |
| Onyango AN | Formation of Aldehydic Phosphatidylcholines during the Anaerobic Decomposition of a Phosphatidylcholine Bearing the 9-Hydroperoxide of Linoleic Acid. | 2016 | Biomed Res Int | pmid:27366754 |
| Champakaew D et al. | Assessment of Angelica sinensis (Oliv.) Diels as a repellent for personal protection against mosquitoes under laboratory and field conditions in northern Thailand. | 2016 | Parasit Vectors | pmid:27357395 |
| Cinelli G et al. | Influence of Maternal Obesity and Gestational Weight Gain on Maternal and Foetal Lipid Profile. | 2016 | Nutrients | pmid:27314385 |
| Kuda O et al. | Docosahexaenoic Acid-Derived Fatty Acid Esters of Hydroxy Fatty Acids (FAHFAs) With Anti-inflammatory Properties. | 2016 | Diabetes | pmid:27313314 |
| Bautista LE | Calcium and linoleic acid supplements in the prevention of preeclampsia. | 2016 | Colomb. Med. | pmid:27226669 |
| Wang S et al. | Linoleic acid and stearic acid elicit opposite effects on AgRP expression and secretion via TLR4-dependent signaling pathways in immortalized hypothalamic N38 cells. | 2016 | Biochem. Biophys. Res. Commun. | pmid:26879142 |
| Kot AM et al. | Rhodotorula glutinis-potential source of lipids, carotenoids, and enzymes for use in industries. | 2016 | Appl. Microbiol. Biotechnol. | pmid:27209039 |
| Mojumdar EH et al. | Stratum corneum lipid matrix: Location of acyl ceramide and cholesterol in the unit cell of the long periodicity phase. | 2016 | Biochim. Biophys. Acta | pmid:27169629 |
| Tel-Çayan G et al. | A new fatty acid ester from an edible mushroom Rhizopogon luteolus. | 2016 | Nat. Prod. Res. | pmid:26987031 |
| Liu G et al. | Biotype Characterization, Developmental Profiling, Insecticide Response and Binding Property of Bemisia tabaci Chemosensory Proteins: Role of CSP in Insect Defense. | 2016 | PLoS ONE | pmid:27167733 |
| Chiba T et al. | The Precise Structures and Stereochemistry of Trihydroxy-linoleates Esterified in Human and Porcine Epidermis and Their Significance in Skin Barrier Function: IMPLICATION OF AN EPOXIDE HYDROLASE IN THE TRANSFORMATIONS OF LINOLEATE. | 2016 | J. Biol. Chem. | pmid:27151221 |
| Abdullah BM et al. | Polyesters Based on Linoleic Acid for Biolubricant Basestocks: Low-Temperature, Tribological and Rheological Properties. | 2016 | PLoS ONE | pmid:27008312 |