Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Bosca F et al. | Photophysical and photochemical characterization of a photosensitizing drug: a combined steady state photolysis and laser flash photolysis study on carprofen. | 1997 | Chem. Res. Toxicol. | pmid:9250417 |
Parmentier HK et al. | Dietary unsaturated fatty acids affect antibody responses and growth of chickens divergently selected for humoral responses to sheep red blood cells. | 1997 | Poult. Sci. | pmid:9251147 |
Howlett NG and Avery SV | Induction of lipid peroxidation during heavy metal stress in Saccharomyces cerevisiae and influence of plasma membrane fatty acid unsaturation. | 1997 | Appl. Environ. Microbiol. | pmid:9251184 |
Siguel E | Essential fatty acid status in patients. | 1997 Jul-Aug | JPEN J Parenter Enteral Nutr | pmid:9252955 |
Castelli F et al. | Dipalmitoylphosphatidylcholine/linoleic acid mixed unilamellar vesicles as model membranes for studies on novel free-radical scavengers. | 1997 | J Pharmacol Toxicol Methods | pmid:9253749 |
Risé P et al. | Effects of simvastatin on the metabolism of polyunsaturated fatty acids and on glycerolipid, cholesterol, and de novo lipid synthesis in THP-1 cells. | 1997 | J. Lipid Res. | pmid:9254057 |
Bakker N et al. | Adipose fatty acids and cancers of the breast, prostate and colon: an ecological study. EURAMIC Study Group. | 1997 | Int. J. Cancer | pmid:9259395 |
Badart-Smook A et al. | Fetal growth is associated positively with maternal intake of riboflavin and negatively with maternal intake of linoleic acid. | 1997 | J Am Diet Assoc | pmid:9259708 |
Feussner I et al. | Structural elucidation of oxygenated storage lipids in cucumber cotyledons. Implication of lipid body lipoxygenase in lipid mobilization during germination. | 1997 | J. Biol. Chem. | pmid:9261186 |
Jenkins TC | Ruminal fermentation and nutrient digestion in sheep fed hydroxyethylsoyamide. | 1997 | J. Anim. Sci. | pmid:9263076 |
Lopez Jimenez JA et al. | Linoleic acid metabolism in primary cultures of adult rat cardiomyocytes is impaired by aging. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9266846 |
Fabritius D et al. | Biotransformation of linoleic acid with the Candida tropicalis M25 mutant. | 1997 | Appl. Microbiol. Biotechnol. | pmid:9274051 |
Batna A et al. | Lipid peroxidation in presence of ebselen. | 1997 | Chem. Phys. Lipids | pmid:9275309 |
Usha S and Balakrishnan A | c-myc, c-H-ras, and IP3 elevation in 18:2 n-6 dependent proliferation of lung cells. | 1997 Jul-Aug | In Vitro Cell. Dev. Biol. Anim. | pmid:9282304 |
Carlson SE | Functional effects of increasing omega-3 fatty acid intake. | 1997 | J. Pediatr. | pmid:9290597 |
Jensen CL et al. | Effect of dietary linoleic/alpha-linolenic acid ratio on growth and visual function of term infants. | 1997 | J. Pediatr. | pmid:9290604 |
López-Nicolás JM et al. | Kinetic characteristics of the enzymatic conversion in presence of cyclodextrins: study of the oxidation of polyunsaturated fatty acids by lipoxygenase. | 1997 | Biochim. Biophys. Acta | pmid:9295158 |
Hall JA et al. | Lipid composition of hepatic and adipose tissues from normal cats and from cats with idiopathic hepatic lipidosis. | 1997 Jul-Aug | J. Vet. Intern. Med. | pmid:9298479 |
de Waart FG et al. | Vitamin E supplementation in elderly lowers the oxidation rate of linoleic acid in LDL. | 1997 | Atherosclerosis | pmid:9298686 |
Rusnak A et al. | Cardiolipin remodeling in a Chinese hamster lung fibroblast cell line deficient in oxidative energy production. | 1997 | J. Bioenerg. Biomembr. | pmid:9298714 |