Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Guarini P et al. | Effects of dietary fish oil and soy phosphatidylcholine on neutrophil fatty acid composition, superoxide release, and adhesion. | 1998 | Inflammation | pmid:9675609 |
Kelly ML et al. | Effect of intake of pasture on concentrations of conjugated linoleic acid in milk of lactating cows. | 1998 | J. Dairy Sci. | pmid:9684170 |
Demmelmair H et al. | Metabolism of U13C-labeled linoleic acid in lactating women. | 1998 | J. Lipid Res. | pmid:9684741 |
Kang LT and Vanderhoek JY | Mono (S) hydroxy fatty acids: novel ligands for cytosolic actin. | 1998 | J. Lipid Res. | pmid:9684751 |
Kato M et al. | Reactivity of soybean lipoxygenase-1 to linoleic acid entrapped in phosphatidylcholine vesicles. | 1998 | J. Biochem. | pmid:9685717 |
Fungwe TV et al. | Fatty acids modulate lecithin:cholesterol acyltransferase secretion independently of effects on triglyceride secretion in primary rat hepatocytes. | 1998 | J. Nutr. | pmid:9687543 |
Letawe C et al. | Digital image analysis of the effect of topically applied linoleic acid on acne microcomedones. | 1998 | Clin. Exp. Dermatol. | pmid:9692305 |
Hsu AF et al. | Characterization of soybean lipoxygenase immobilized in cross-linked phyllosilicates. | 1998 | Biotechnol. Appl. Biochem. | pmid:9693089 |
Goodrich-Tanrikulu M et al. | Changes in fatty acid composition of Neurospora crassa accompany sexual development and ascospore germination. | 1998 | Microbiology (Reading, Engl.) | pmid:9695905 |
Yamaguchi H et al. | High transepidermal water loss induces fatty acid synthesis and cutaneous fatty acid-binding protein expression in rat skin. | 1998 | J. Dermatol. Sci. | pmid:9697049 |