Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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O'Donnell VB et al. | 15-Lipoxygenase catalytically consumes nitric oxide and impairs activation of guanylate cyclase. | 1999 | J. Biol. Chem. | pmid:10400618 |
Andersen LF et al. | Evaluation of a food frequency questionnaire with weighed records, fatty acids, and alpha-tocopherol in adipose tissue and serum. | 1999 | Am. J. Epidemiol. | pmid:10400557 |
Ingkaninan K et al. | Interference of linoleic acid fraction in some receptor binding assays. | 1999 | J. Nat. Prod. | pmid:10395519 |
Hidaka T et al. | Screening of microbial products modifying the action of leptin (obese gene product) by a biosensor. | 1999 | J. Antibiot. | pmid:10395281 |
Ando H et al. | Possible involvement of proteolytic degradation of tyrosinase in the regulatory effect of fatty acids on melanogenesis. | 1999 | J. Lipid Res. | pmid:10393216 |
Su HM et al. | Linoleic acid kinetics and conversion to arachidonic acid in the pregnant and fetal baboon. | 1999 | J. Lipid Res. | pmid:10393215 |
Jeppesen PB et al. | Differences in essential fatty acid requirements by enteral and parenteral routes of administration in patients with fat malabsorption. | 1999 | Am. J. Clin. Nutr. | pmid:10393142 |
Jiang J et al. | Relation between the intake of milk fat and the occurrence of conjugated linoleic acid in human adipose tissue. | 1999 | Am. J. Clin. Nutr. | pmid:10393134 |
Greenberg D et al. | Differential satiating effects of fats in the small intestine of obesity-resistant and obesity-prone rats. | 1999 | Physiol. Behav. | pmid:10386906 |
Parodi PW | Conjugated linoleic acid and other anticarcinogenic agents of bovine milk fat. | 1999 | J. Dairy Sci. | pmid:10386321 |