Linoleic acid
Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoleic acid?
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoleic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with Linoleic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoleic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Linoleic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoleic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Jung S et al. | Effect of dietary mixture of gallic acid and linoleic acid on antioxidative potential and quality of breast meat from broilers. | 2010 | Meat Sci. | pmid:20609528 |
| Ohmori H et al. | Dietary linoleic acid and glucose enhances azoxymethane-induced colon cancer and metastases via the expression of high-mobility group box 1. | 2010 | Pathobiology | pmid:20616616 |
| Bartók T et al. | Identification of the first fumonisin mycotoxins with three acyl groups by ESI-ITMS and ESI-TOFMS following RP-HPLC separation: palmitoyl, linoleoyl and oleoyl EFB₠fumonisin isomers from a solid culture of Fusarium verticillioides. | 2010 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:21108092 |
| Maia MR et al. | Toxicity of unsaturated fatty acids to the biohydrogenating ruminal bacterium, Butyrivibrio fibrisolvens. | 2010 | BMC Microbiol. | pmid:20167098 |
| Dailey MJ et al. | Nutrient specific feeding and endocrine effects of jejunal infusions. | 2010 | Obesity (Silver Spring) | pmid:20134410 |
| RodrÃguez AM et al. | Time-course effects of increased fatty acid supply on the expression of genes involved in lipid/glucose metabolism in muscle cells. | 2010 | Cell. Physiol. Biochem. | pmid:20110694 |
| Won JC et al. | Peroxisome proliferator-activated receptor-gamma coactivator 1-alpha overexpression prevents endothelial apoptosis by increasing ATP/ADP translocase activity. | 2010 | Arterioscler. Thromb. Vasc. Biol. | pmid:19965780 |
| Dimri M et al. | Dietary omega-3 polyunsaturated fatty acids suppress expression of EZH2 in breast cancer cells. | 2010 | Carcinogenesis | pmid:19969553 |
| Olveira G et al. | Fatty acid supplements improve respiratory, inflammatory and nutritional parameters in adults with cystic fibrosis. | 2010 | Arch. Bronconeumol. | pmid:20045240 |
| Jernerén F et al. | Reaction mechanism of 5,8-linoleate diol synthase, 10R-dioxygenase, and 8,11-hydroperoxide isomerase of Aspergillus clavatus. | 2010 | Biochim. Biophys. Acta | pmid:20045744 |
| Paraszkiewicz K et al. | Lipid peroxidation in the fungus Curvularia lunata exposed to nickel. | 2010 | Arch. Microbiol. | pmid:20047047 |
| Esmaeili MA and Sonboli A | Antioxidant, free radical scavenging activities of Salvia brachyantha and its protective effect against oxidative cardiac cell injury. | 2010 | Food Chem. Toxicol. | pmid:20036303 |
| Renaville B et al. | Plasma and follicular fluid fatty acid profiles in dairy cows. | 2010 | Reprod. Domest. Anim. | pmid:19055554 |
| Kubala L et al. | Modulation of arachidonic and linoleic acid metabolites in myeloperoxidase-deficient mice during acute inflammation. | 2010 | Free Radic. Biol. Med. | pmid:20156554 |
| Jernerén F et al. | Linoleate 9R-dioxygenase and allene oxide synthase activities of Aspergillus terreus. | 2010 | Arch. Biochem. Biophys. | pmid:20043865 |
| Bradbury KE et al. | The serum fatty acids myristic acid and linoleic acid are better predictors of serum cholesterol concentrations when measured as molecular percentages rather than as absolute concentrations. | 2010 | Am. J. Clin. Nutr. | pmid:19955401 |
| Lábaque MC et al. | Effect of age and body weight of Greater Rhea (Rhea americana) females on egg number, size and composition. | 2010 | Br. Poult. Sci. | pmid:21161792 |
| Fekete K and Decsi T | Long-chain polyunsaturated fatty acids in inborn errors of metabolism. | 2010 | Nutrients | pmid:22254065 |
| Zidi A et al. | Pleiotropic effects of the goat prolactin receptor genotype on milk fatty acid composition. | 2010 | Domest. Anim. Endocrinol. | pmid:20399061 |
| Peoples GE and McLennan PL | Dietary fish oil reduces skeletal muscle oxygen consumption, provides fatigue resistance and improves contractile recovery in the rat in vivo hindlimb. | 2010 | Br. J. Nutr. | pmid:20691135 |
| Köse EO et al. | Chemical composition, antimicrobial and antioxidant activities of the essential oils of Sideritis erythrantha Boiss. and Heldr. (var. erythrantha and var. cedretorum P.H. Davis) endemic in Turkey. | 2010 | Food Chem. Toxicol. | pmid:20670669 |
| Strandvik B | Fatty acid metabolism in cystic fibrosis. | 2010 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:20673710 |
| Noel JT et al. | Specific responses of Salmonella enterica to tomato varieties and fruit ripeness identified by in vivo expression technology. | 2010 | PLoS ONE | pmid:20824208 |
| Macouzet M et al. | Genetic and structural comparison of linoleate isomerases from selected food-grade bacteria. | 2010 | J. Appl. Microbiol. | pmid:20825518 |
| Collin F et al. | Experimental evidence of the reciprocal oxidation of Bovine Serum Albumin and Linoleate in aqueous solution, initiated by HO* free radicals. | 2010 | Biochimie | pmid:20685376 |
| Calder PC | The American Heart Association advisory on n-6 fatty acids: evidence based or biased evidence? | 2010 | Br. J. Nutr. | pmid:21118616 |
| Ramsden CE et al. | n-6 fatty acid-specific and mixed polyunsaturate dietary interventions have different effects on CHD risk: a meta-analysis of randomised controlled trials. | 2010 | Br. J. Nutr. | pmid:21118617 |
| Guo JJ and Hu CH | Mechanism of chain termination in lipid peroxidation by carotenes: a theoretical study. | 2010 | J Phys Chem B | pmid:21105679 |
| Wu TC et al. | Fatty acid composition of Taiwanese human milk. | 2010 | J Chin Med Assoc | pmid:21093826 |
| West SG et al. | Effects of diets high in walnuts and flax oil on hemodynamic responses to stress and vascular endothelial function. | 2010 | J Am Coll Nutr | pmid:21677123 |
| Demir AS and Talpur FN | Chemoenzymatic conversion of linoleic acid into conjugated linoleic acid. | 2010 | J. Agric. Food Chem. | pmid:20058923 |
| Aluf Y et al. | Specific oxidative stress profile associated with partial striatal dopaminergic depletion by 6-hydroxydopamine as assessed by a novel multifunctional marker molecule. | 2010 | Free Radic. Res. | pmid:20370558 |
| Tume RK et al. | Enriching M. sternomandibularis with alpha-tocopherol by dietary means does not protect against the lipid oxidation caused by high-pressure processing. | 2010 | Meat Sci. | pmid:20374755 |
| Berthelot V et al. | Utilization of extruded linseed to modify fatty composition of intensively-reared lamb meat: effect of associated cereals (wheat vs. corn) and linoleic acid content of the diet. | 2010 | Meat Sci. | pmid:20374762 |
| Della Casa G et al. | Performance and fat quality of heavy pigs fed maize differing in linoleic acid content. | 2010 | Meat Sci. | pmid:20374768 |
| Aldai N et al. | Double-muscling character influences the trans-18:1 and conjugated linoleic acid profiles in concentrate-fed yearling bulls. | 2010 | Meat Sci. | pmid:20374865 |
| Xiao C et al. | Synthesis of methyl-substituted xanthotoxol to clarify prooxidant effect of methyl on radical-induced oxidation of DNA. | 2010 | Eur J Med Chem | pmid:20332056 |
| Bitis L et al. | Flavonoids and antioxidant activity of Rosa agrestis leaves. | 2010 | Nat. Prod. Res. | pmid:20397108 |
| Kamkar A et al. | The antioxidative effect of Iranian Mentha pulegium extracts and essential oil in sunflower oil. | 2010 | Food Chem. Toxicol. | pmid:20385193 |
| Sarikurkcu C et al. | Essential oil composition and antioxidant activity of Thymus longicaulis C. Presl subsp. longicaulis var. longicaulis. | 2010 | Food Chem. Toxicol. | pmid:20385197 |
| Litvinov D et al. | Anti-atherosclerotic actions of azelaic acid, an end product of linoleic acid peroxidation, in mice. | 2010 | Atherosclerosis | pmid:19880116 |
| Friesen RW and Innis SM | Linoleic acid is associated with lower long-chain n-6 and n-3 fatty acids in red blood cell lipids of Canadian pregnant women. | 2010 | Am. J. Clin. Nutr. | pmid:19923368 |
| Runyon JB et al. | Parasitism by Cuscuta pentagona sequentially induces JA and SA defence pathways in tomato. | 2010 | Plant Cell Environ. | pmid:19930126 |
| Matsuoka T et al. | Elevated dietary linoleic acid increases gastric carcinoma cell invasion and metastasis in mice. | 2010 | Br. J. Cancer | pmid:20842125 |
| Liu S and Han B | Differential expression pattern of an acidic 9/13-lipoxygenase in flower opening and senescence and in leaf response to phloem feeders in the tea plant. | 2010 | BMC Plant Biol. | pmid:20969806 |
| Benammar C et al. | Zizyphus lotus L. (Desf.) modulates antioxidant activity and human T-cell proliferation. | 2010 | BMC Complement Altern Med | pmid:20868496 |
| Lu X et al. | Linoleic acid suppresses colorectal cancer cell growth by inducing oxidant stress and mitochondrial dysfunction. | 2010 | Lipids Health Dis | pmid:20868498 |
| Brodhun F et al. | PpoC from Aspergillus nidulans is a fusion protein with only one active haem. | 2010 | Biochem. J. | pmid:19878096 |
| Zengin G et al. | In vitro antioxidant capacities and fatty acid compositions of three Centaurea species collected from Central Anatolia region of Turkey. | 2010 | Food Chem. Toxicol. | pmid:20600531 |
| Shen Q et al. | Antioxidant activity in vitro of the selenium-contained protein from the Se-enriched Bifidobacterium animalis 01. | 2010 | Anaerobe | pmid:20601030 |