Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Liu HC et al. | Transcriptome changes in Polygonum multiflorum Thunb. roots induced by methyl jasmonate. | 2015 | J Zhejiang Univ Sci B | pmid:26642186 |
Liang S et al. | Physicochemical Properties and Fatty Acid Profiles of Elaeagnus mollis Diels Nut Oils. | 2015 | J Oleo Sci | pmid:26632946 |
Qian Z et al. | Mulberry fruit prevents LPS-induced NF-κB/pERK/MAPK signals in macrophages and suppresses acute colitis and colorectal tumorigenesis in mice. | 2015 | Sci Rep | pmid:26615818 |
Salehi R et al. | A prepartum diet supplemented with oilseeds high in oleic or linoleic acid reduced GnRH-induced LH release in dairy cows during second week postpartum. | 2015 | Reprod. Biol. Endocrinol. | pmid:26138920 |
Grevengoed TJ et al. | Acyl-CoA synthetase 1 deficiency alters cardiolipin species and impairs mitochondrial function. | 2015 | J. Lipid Res. | pmid:26136511 |
Hasiewicz-Derkacz K et al. | Natural phenolics greatly increase flax (Linum usitatissimum) oil stability. | 2015 | BMC Biotechnol. | pmid:26123633 |
Rosero DS et al. | Impact of dietary lipids on sow milk composition and balance of essential fatty acids during lactation in prolific sows. | 2015 | J. Anim. Sci. | pmid:26115280 |
Negrini R et al. | pH-responsive lyotropic liquid crystals and their potential therapeutic role in cancer treatment. | 2015 | Chem. Commun. (Camb.) | pmid:25783035 |
Liu H et al. | Transient receptor potential vanilloid 1 gene deficiency ameliorates hepatic injury in a mouse model of chronic binge alcohol-induced alcoholic liver disease. | 2015 | Am. J. Pathol. | pmid:25447051 |
Reinders I et al. | Plasma phospholipid PUFAs are associated with greater muscle and knee extension strength but not with changes in muscle parameters in older adults. | 2015 | J. Nutr. | pmid:25355842 |