Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Livraghi S et al. | Decreasing the oxidative potential of TiO(2) nanoparticles through modification of the surface with carbon: a new strategy for the production of safe UV filters. | 2010 | Chem. Commun. (Camb.) | pmid:20938530 |
Caroprese M et al. | Flaxseed supplementation improves fatty acid profile of cow milk. | 2010 | J. Dairy Sci. | pmid:20494167 |
Wien M et al. | Decreasing the linoleic acid to alpha-linolenic acid diet ratio increases eicosapentaenoic acid in erythrocytes in adults. | 2010 | Lipids | pmid:20496049 |
Can-Karabulut DC et al. | Influence of experimental provisional cements containing zeolite, bone hydroxyapatite and linoleic Acid on bond strength of composite to dentin in vitro. | 2010 | J Adhes Dent | pmid:20157651 |
Maia MR et al. | Toxicity of unsaturated fatty acids to the biohydrogenating ruminal bacterium, Butyrivibrio fibrisolvens. | 2010 | BMC Microbiol. | pmid:20167098 |
Hirai S et al. | Loss of sense transgene-induced post-transcriptional gene silencing by sequential introduction of the same transgene sequences in tobacco. | 2010 | FEBS J. | pmid:20180844 |
Gammill W et al. | Comparative study of high-linoleic acid vegetable oils for the production of conjugated linoleic acid. | 2010 | J. Agric. Food Chem. | pmid:20136082 |
Harris W | Omega-6 and omega-3 fatty acids: partners in prevention. | 2010 | Curr Opin Clin Nutr Metab Care | pmid:20145438 |
Thornhill JA et al. | Pathways for the influx of molecules into cercariae of Schistosoma mansoni during skin penetration. | 2010 | Parasitology | pmid:20128942 |
Dailey MJ et al. | Nutrient specific feeding and endocrine effects of jejunal infusions. | 2010 | Obesity (Silver Spring) | pmid:20134410 |
Combet E et al. | Development of an in vitro system combining aqueous and lipid phases as a tool to understand gastric nitrosation. | 2010 | Rapid Commun. Mass Spectrom. | pmid:20112267 |
Castellanos P et al. | Changes in fatty acid profiles in testis and spermatozoa of red deer exposed to metal pollution. | 2010 | Reprod. Toxicol. | pmid:20096347 |
Coyral-Castel S et al. | Effects of unsaturated fatty acids on progesterone secretion and selected protein kinases in goat granulosa cells. | 2010 | Domest. Anim. Endocrinol. | pmid:20097509 |
Nakamura T et al. | Excessive fat restriction might promote the recurrence of colorectal tumors. | 2010 | Nutr Cancer | pmid:20099189 |
Beevi SS et al. | Polyphenolics profile, antioxidant and radical scavenging activity of leaves and stem of Raphanus sativus L. | 2010 | Plant Foods Hum Nutr | pmid:20072818 |
Privé F et al. | Temperature and duration of heating of sunflower oil affect ruminal biohydrogenation of linoleic acid in vitro. | 2010 | J. Dairy Sci. | pmid:20105542 |
RodrÃguez AM et al. | Time-course effects of increased fatty acid supply on the expression of genes involved in lipid/glucose metabolism in muscle cells. | 2010 | Cell. Physiol. Biochem. | pmid:20110694 |
Dimri M et al. | Dietary omega-3 polyunsaturated fatty acids suppress expression of EZH2 in breast cancer cells. | 2010 | Carcinogenesis | pmid:19969553 |
Olveira G et al. | Fatty acid supplements improve respiratory, inflammatory and nutritional parameters in adults with cystic fibrosis. | 2010 | Arch. Bronconeumol. | pmid:20045240 |
Li Y et al. | Bone mineral content is positively correlated to n-3 fatty acids in the femur of growing rats. | 2010 | Br. J. Nutr. | pmid:20420751 |
Even P et al. | Postprandial effects of a lipid-rich meal in the rat are modulated by the degree of unsaturation of 18C fatty acids. | 2010 | Metab. Clin. Exp. | pmid:19775712 |
Kubala L et al. | Modulation of arachidonic and linoleic acid metabolites in myeloperoxidase-deficient mice during acute inflammation. | 2010 | Free Radic. Biol. Med. | pmid:20156554 |
Gholivand MB et al. | Chemical composition and antioxidant activities of the essential oil and methanol extracts of Psammogeton canescens. | 2010 | Food Chem. Toxicol. | pmid:19748545 |
Kim BS et al. | Effect of surfactant on the production of oxygenated unsaturated fatty acids by Bacillus megaterium ALA2. | 2010 | N Biotechnol | pmid:19748603 |
Joshi SC et al. | Antioxidant and antibacterial activities of the leaf essential oils of Himalayan Lauraceae species. | 2010 | Food Chem. Toxicol. | pmid:19766161 |
Alvaro A et al. | Polyunsaturated fatty acids down-regulate in vitro expression of the key intestinal cholesterol absorption protein NPC1L1: no effect of monounsaturated nor saturated fatty acids. | 2010 | J. Nutr. Biochem. | pmid:19443194 |
Walloschke B et al. | Enrichment of RAW264.7 macrophages with essential 18-carbon fatty acids affects both respiratory burst and production of immune modulating cytokines. | 2010 | J. Nutr. Biochem. | pmid:19447017 |
Huang CB et al. | Antimicrobial activity of n-6, n-7 and n-9 fatty acids and their esters for oral microorganisms. | 2010 | Arch. Oral Biol. | pmid:20541177 |
Rodrigues HG et al. | Dietary free oleic and linoleic acid enhances neutrophil function and modulates the inflammatory response in rats. | 2010 | Lipids | pmid:20730605 |
Tel G et al. | Chemical composition of the essential oil and hexane extract of Salvia chionantha and their antioxidant and anticholinesterase activities. | 2010 | Food Chem. Toxicol. | pmid:20732375 |
Gutiérrez-Correa J | Trypanosoma cruzi dihydrolipoamide dehydrogenase as target of reactive metabolites generated by cytochrome c/hydrogen peroxide (or linoleic acid hydroperoxide)/phenol systems. | 2010 | Free Radic. Res. | pmid:20815787 |
Serhan Z et al. | Complete determination of natural site-specific enantio-isotopomeric excesses in linoleic acid using natural abundance deuterium 2D NMR in polypeptide mesophases. | 2010 | Chem. Commun. (Camb.) | pmid:20721385 |
Bolton B and Halpern BP | Orthonasal and retronasal but not oral-cavity-only discrimination of vapor-phase fatty acids. | 2010 | Chem. Senses | pmid:20100787 |
Lu XF et al. | Colorectal cancer cell growth inhibition by linoleic acid is related to fatty acid composition changes. | 2010 | J Zhejiang Univ Sci B | pmid:21121070 |
Luo H et al. | The In vitro antioxidant properties of chinese highland lichens. | 2010 | J. Microbiol. Biotechnol. | pmid:21124057 |
Olszewska MA et al. | Assessment of the content of phenolics and antioxidant action of inflorescences and leaves of selected species from the genus Sorbus sensu stricto. | 2010 | Molecules | pmid:21127463 |
Gotoh N et al. | Highly unsaturated fatty acid might act as an antioxidant in emulsion system oxidized by azo compound. | 2010 | J Oleo Sci | pmid:21099140 |
Wu TC et al. | Fatty acid composition of Taiwanese human milk. | 2010 | J Chin Med Assoc | pmid:21093826 |
West SG et al. | Effects of diets high in walnuts and flax oil on hemodynamic responses to stress and vascular endothelial function. | 2010 | J Am Coll Nutr | pmid:21677123 |
Duckett SK and Gillis MH | Effects of oil source and fish oil addition on ruminal biohydrogenation of fatty acids and conjugated linoleic acid formation in beef steers fed finishing diets. | 2010 | J. Anim. Sci. | pmid:20348369 |
Tremblay-Mercier J et al. | Bezafibrate mildly stimulates ketogenesis and fatty acid metabolism in hypertriglyceridemic subjects. | 2010 | J. Pharmacol. Exp. Ther. | pmid:20404010 |
Georgiadi A et al. | Induction of cardiac Angptl4 by dietary fatty acids is mediated by peroxisome proliferator-activated receptor beta/delta and protects against fatty acid-induced oxidative stress. | 2010 | Circ. Res. | pmid:20378851 |
Marei WF et al. | Impact of linoleic acid on bovine oocyte maturation and embryo development. | 2010 | Reproduction | pmid:20215338 |
Lau BY et al. | Influence of high-fat diet from differential dietary sources on bone mineral density, bone strength, and bone fatty acid composition in rats. | 2010 | Appl Physiol Nutr Metab | pmid:20962915 |
Liu S and Han B | Differential expression pattern of an acidic 9/13-lipoxygenase in flower opening and senescence and in leaf response to phloem feeders in the tea plant. | 2010 | BMC Plant Biol. | pmid:20969806 |
Khiaosa-Ard R et al. | Transfer of linoleic and linolenic acid from feed to milk in cows fed isoenergetic diets differing in proportion and origin of concentrates and roughages. | 2010 | J. Dairy Res. | pmid:20482940 |
Sahoo PK and Behera P | Synthesis and biological screening of some novel amidocarbamate derivatives of ketoprofen. | 2010 | Eur J Med Chem | pmid:20434240 |
Campoy C et al. | [Update of knowledge, recommendations and full consensus about the role of long chain polyunsaturated fatty acids in pregnancy, lactating period and first year of life.Asociación Española de PediatrÃa. Sociedad Española de GinecologÃa y Obstetricia. Sociedad Española de Nutrición Comunitaria. Academia Española deNutrición y Ciencias de la Alimentación]. | 2010 | Med Clin (Barc) | pmid:20434734 |
Goicoechea E and Guillen MD | Analysis of hydroperoxides, aldehydes and epoxides by 1H nuclear magnetic resonance in sunflower oil oxidized at 70 and 100 degrees C. | 2010 | J. Agric. Food Chem. | pmid:20438132 |
Macouzet M et al. | Genetic and functional aspects of linoleate isomerase in Lactobacillus acidophilus. | 2010 | Appl. Microbiol. Biotechnol. | pmid:20461509 |