Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Latour MA et al. | Effects of conjugated linoleic acid. 2. Embryonic and neonatal growth and circulating lipids. | 2000 | Poult. Sci. | pmid:10875762 |
Latour MA et al. | Effects of conjugated linoleic acid. 1. Fatty acid modification of yolks and neonatal fatty acid metabolism. | 2000 | Poult. Sci. | pmid:10875761 |
Decsi T and Koletzko B | Effects of protein-energy malnutrition and human immunodeficiency virus-1 infection on essential fatty acid metabolism in children. | 2000 | Nutrition | pmid:10869902 |
Watanabe T et al. | Formation of acyl radical in lipid peroxidation of linoleic acid by manganese-dependent peroxidase from Ceriporiopsis subvermispora and Bjerkandera adusta. | 2000 | Eur. J. Biochem. | pmid:10866827 |
Yoshiki Y et al. | Chemiluminescence and reactive oxygen scavenging activities of the hydrogen peroxide/gallic acid/lactoperoxidase system. | 2000 May-Jun | Luminescence | pmid:10862147 |
Williams JP et al. | The role of phosphatidylcholine in fatty acid exchange and desaturation in Brassica napus L. leaves. | 2000 | Biochem. J. | pmid:10861220 |
Smith JC et al. | Orosensory factors in the ingestion of corn oil/sucrose mixtures by the rat. | 2000 Apr 1-15 | Physiol. Behav. | pmid:10854925 |
Richieri GV et al. | Fatty acid binding proteins from different tissues show distinct patterns of fatty acid interactions. | 2000 | Biochemistry | pmid:10852718 |
McHowat J and Creer MH | Selective plasmalogen substrate utilization by thrombin-stimulated Ca(2+)-independent PLA(2) in cardiomyocytes. | 2000 | Am. J. Physiol. Heart Circ. Physiol. | pmid:10843891 |
Maccarrone M et al. | Activation of different lipoxygenase isozymes induces apoptosis in human erythroleukemia and neuroblastoma cells. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10833416 |
Bloodsworth A et al. | Manganese-porphyrin reactions with lipids and lipoproteins. | 2000 | Free Radic. Biol. Med. | pmid:10832063 |
Tokumura A et al. | Structural identification of phosphatidylcholines having an oxidatively shortened linoleate residue generated through its oxygenation with soybean or rabbit reticulocyte lipoxygenase. | 2000 | J. Lipid Res. | pmid:10828088 |
Azain MJ et al. | Dietary conjugated linoleic acid reduces rat adipose tissue cell size rather than cell number. | 2000 | J. Nutr. | pmid:10827208 |
Peebles ED et al. | Effects of dietary fat type and level on broiler breeder performance. | 2000 | Poult. Sci. | pmid:10824949 |
Tominaga K et al. | Effect of linoleic acid-albumin on post-thaw survival of in vitro-produced bovine embryos at the 16-cell stage. | 2000 | J. Vet. Med. Sci. | pmid:10823739 |
Dhiman TR et al. | Conjugated linoleic acid (CLA) content of milk from cows offered diets rich in linoleic and linolenic acid. | 2000 | J. Dairy Sci. | pmid:10821577 |
Pham TQ et al. | Antioxidant properties of crocin from Gardenia jasminoides Ellis and study of the reactions of crocin with linoleic acid and crocin with oxygen. | 2000 | J. Agric. Food Chem. | pmid:10820042 |
Decsi T et al. | Effect of type of early infant feeding on fatty acid composition of plasma lipid classes in full-term infants during the second 6 months of life. | 2000 | J. Pediatr. Gastroenterol. Nutr. | pmid:10817286 |
Lapillonne A et al. | Effects of liver transplantation on long-chain polyunsaturated fatty acid status in infants with biliary atresia. | 2000 | J. Pediatr. Gastroenterol. Nutr. | pmid:10817283 |
Kachhap SK et al. | Effect of omega-6 polyunsaturated fatty acid (linoleic acid) on BRCA1 gene expression in MCF-7 cell line. | 2000 | Cancer Lett. | pmid:10806298 |