Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Pornputtapitak W et al. | Development of γ-Oryzanol Rich Extract from Leum Pua Glutinous Rice Bran Loaded Nanostructured Lipid Carriers for Topical Delivery. | 2018 | J Oleo Sci | pmid:29367479 |
Wang X et al. | From the Cover: Identification of Natural Products as Inhibitors of Human Organic Anion Transporters (OAT1 and OAT3) and Their Protective Effect on Mercury-Induced Toxicity. | 2018 | Toxicol. Sci. | pmid:29045746 |
Liu Q et al. | Dietary n-6:n-3 ratio and Vitamin E improve motility characteristics in association with membrane properties of boar spermatozoa. | 2017 Mar-Apr | Asian J. Androl. | pmid:26763547 |
Monastero R et al. | Methylation patterns of Vegfb promoter are associated with gene and protein expression levels: the effects of dietary fatty acids. | 2017 | Eur J Nutr | pmid:26707994 |
Fan Y et al. | Study of the pH-sensitive mechanism of tumor-targeting liposomes. | 2017 | Colloids Surf B Biointerfaces | pmid:27940165 |
Alsharari ZD et al. | Serum Fatty Acids, Desaturase Activities and Abdominal Obesity - A Population-Based Study of 60-Year Old Men and Women. | 2017 | PLoS ONE | pmid:28125662 |
Muralikumar S et al. | Probing the intermolecular interactions of PPARγ-LBD with polyunsaturated fatty acids and their anti-inflammatory metabolites to infer most potential binding moieties. | 2017 | Lipids Health Dis | pmid:28109294 |
Fujii M | Pathogenesis of Diet-induced Atopic Dermatitis in Hairless Mice. | 2017 | Yakugaku Zasshi | pmid:28049895 |
Turell L et al. | The Chemical Basis of Thiol Addition to Nitro-conjugated Linoleic Acid, a Protective Cell-signaling Lipid. | 2017 | J. Biol. Chem. | pmid:27923813 |
Nury T et al. | 7-Ketocholesterol is increased in the plasma of X-ALD patients and induces peroxisomal modifications in microglial cells: Potential roles of 7-ketocholesterol in the pathophysiology of X-ALD. | 2017 | J. Steroid Biochem. Mol. Biol. | pmid:27041118 |