Linoleic acid

Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.

Cross Reference

Introduction

To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoleic acid?

Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoleic acid

PubChem Associated disorders and diseases

What pathways are associated with Linoleic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with Linoleic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoleic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Linoleic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoleic acid

Download all related citations
Per page 10 20 50 100 | Total 4513
Authors Title Published Journal PubMed Link
Mito F et al. Oxygen concentration dependence of lipid peroxidation and lipid-derived radical generation: application of profluorescent nitroxide switch. 2011 Free Radic. Res. pmid:21736483
Yahya A et al. Effect of J-coupling on lipid composition determination with localized proton magnetic resonance spectroscopy at 9.4 T. 2011 J Magn Reson Imaging pmid:21953706
Yang Y et al. Synthesis and antioxidant capacities of hydroxyl derivatives of cinnamoylphenethylamine in protecting DNA and scavenging radicals. 2011 Free Radic. Res. pmid:21128731
Mihaljević B et al. Linoleic acid peroxidation vs. isomerization: a biomimetic model of free radical reactivity in the presence of thiols. 2011 Org. Biomol. Chem. pmid:21442126
Blum JL et al. Profiling of fatty acids released during calcium-induced mitochondrial permeability transition in isolated rabbit kidney cortex mitochondria. 2011 Toxicol In Vitro pmid:21443943
Salem N and Kuratko CN Lack of evidence for increased α-linolenic acid metabolism in vegetarians. 2011 Am. J. Clin. Nutr. pmid:21430120
McCusker MM and Grant-Kels JM Healing fats of the skin: the structural and immunologic roles of the omega-6 and omega-3 fatty acids. 2010 Jul-Aug Clin. Dermatol. pmid:20620762
Zovko Koncić M et al. Evaluation of antioxidant activities and phenolic content of Berberis vulgaris L. and Berberis croatica Horvat. 2010 Aug-Sep Food Chem. Toxicol. pmid:20488218
Hajlaoui H et al. Chemical composition and biological activities of Tunisian Cuminum cyminum L. essential oil: a high effectiveness against Vibrio spp. strains. 2010 Aug-Sep Food Chem. Toxicol. pmid:20488223
Jung S et al. Effect of dietary mixture of gallic acid and linoleic acid on antioxidative potential and quality of breast meat from broilers. 2010 Meat Sci. pmid:20609528
Feldstein AE et al. Mass spectrometric profiling of oxidized lipid products in human nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. 2010 J. Lipid Res. pmid:20631297
Wang L et al. [Effects of linoleic acid on intracellular calcium concentration in primarily cultured rat pancreatic β-cells and underlying mechanism]. 2010 Sheng Li Xue Bao pmid:21170499
Khiaosa-ard R et al. Methods of emulsifying linoleic acid in biohydrogenation studies in vitro may bias the resulting fatty acid profiles. 2010 Lipids pmid:20582723
Delhanty PJ et al. Unsaturated fatty acids prevent desensitization of the human growth hormone secretagogue receptor by blocking its internalization. 2010 Am. J. Physiol. Endocrinol. Metab. pmid:20587751
Ross RA et al. Differential effects of hypothalamic long-chain fatty acid infusions on suppression of hepatic glucose production. 2010 Am. J. Physiol. Endocrinol. Metab. pmid:20647558
Ohmori H et al. Dietary linoleic acid and glucose enhances azoxymethane-induced colon cancer and metastases via the expression of high-mobility group box 1. 2010 Pathobiology pmid:20616616
Bartók T et al. Identification of the first fumonisin mycotoxins with three acyl groups by ESI-ITMS and ESI-TOFMS following RP-HPLC separation: palmitoyl, linoleoyl and oleoyl EFB₁ fumonisin isomers from a solid culture of Fusarium verticillioides. 2010 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:21108092
Gao F et al. Quantifying conversion of linoleic to arachidonic and other n-6 polyunsaturated fatty acids in unanesthetized rats. 2010 J. Lipid Res. pmid:20622136
Herdmann A et al. Effect of dietary n-3 and n-6 PUFA on lipid composition of different tissues of German Holstein bulls and the fate of bioactive fatty acids during processing. 2010 J. Agric. Food Chem. pmid:20597504
Zaman MM et al. Linoleic acid supplementation results in increased arachidonic acid and eicosanoid production in CF airway cells and in cftr-/- transgenic mice. 2010 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:20656894
Frangioudakis G et al. Saturated- and n-6 polyunsaturated-fat diets each induce ceramide accumulation in mouse skeletal muscle: reversal and improvement of glucose tolerance by lipid metabolism inhibitors. 2010 Endocrinology pmid:20660065
Beezhold BL et al. Vegetarian diets are associated with healthy mood states: a cross-sectional study in seventh day adventist adults. 2010 Nutr J pmid:20515497
Sorrentino F et al. Impact of linoleic acid supplementation on lovastatin production in Aspergillus terreus cultures. 2010 Appl. Microbiol. Biotechnol. pmid:20571794
Tu WC et al. Omega-3 long chain fatty acid synthesis is regulated more by substrate levels than gene expression. 2010 Prostaglandins Leukot. Essent. Fatty Acids pmid:20573490
Vukovic N et al. An efficient synthesis and antioxidant properties of novel imino and amino derivatives of 4-hydroxy coumarins. 2010 Arch. Pharm. Res. pmid:20191339
Pauloin A et al. Oleate and linoleate stimulate degradation of β-casein in prolactin-treated HC11 mouse mammary epithelial cells. 2010 Cell Tissue Res. pmid:20182891
Goebel AS et al. Dermal targeting using colloidal carrier systems with linoleic acid. 2010 Eur J Pharm Biopharm pmid:20170728
Esmaeili MA and Sonboli A Antioxidant, free radical scavenging activities of Salvia brachyantha and its protective effect against oxidative cardiac cell injury. 2010 Food Chem. Toxicol. pmid:20036303
Patwardhan AM et al. Heat generates oxidized linoleic acid metabolites that activate TRPV1 and produce pain in rodents. 2010 J. Clin. Invest. pmid:20424317
Brown DA and Passmore GM Some new insights into the molecular mechanisms of pain perception. 2010 J. Clin. Invest. pmid:20424321
Renaville B et al. Plasma and follicular fluid fatty acid profiles in dairy cows. 2010 Reprod. Domest. Anim. pmid:19055554
Li YF et al. Properties of synthetic homoisoflavonoids to reduce oxidants and to protect linoleic acid and dna against oxidation. 2010 J. Agric. Food Chem. pmid:20199083
Takahashi S et al. The occurrence of renin inhibitor in rice: isolation, identification, and structure-function relationship. 2010 Biosci. Biotechnol. Biochem. pmid:20699562
Calder PC The American Heart Association advisory on n-6 fatty acids: evidence based or biased evidence? 2010 Br. J. Nutr. pmid:21118616
Guo JJ and Hu CH Mechanism of chain termination in lipid peroxidation by carotenes: a theoretical study. 2010 J Phys Chem B pmid:21105679
Aluf Y et al. Specific oxidative stress profile associated with partial striatal dopaminergic depletion by 6-hydroxydopamine as assessed by a novel multifunctional marker molecule. 2010 Free Radic. Res. pmid:20370558
Tume RK et al. Enriching M. sternomandibularis with alpha-tocopherol by dietary means does not protect against the lipid oxidation caused by high-pressure processing. 2010 Meat Sci. pmid:20374755
Berthelot V et al. Utilization of extruded linseed to modify fatty composition of intensively-reared lamb meat: effect of associated cereals (wheat vs. corn) and linoleic acid content of the diet. 2010 Meat Sci. pmid:20374762
Della Casa G et al. Performance and fat quality of heavy pigs fed maize differing in linoleic acid content. 2010 Meat Sci. pmid:20374768
Aldai N et al. Double-muscling character influences the trans-18:1 and conjugated linoleic acid profiles in concentrate-fed yearling bulls. 2010 Meat Sci. pmid:20374865
Christensen KB et al. Identification of bioactive compounds from flowers of black elder (Sambucus nigra L.) that activate the human peroxisome proliferator-activated receptor (PPAR) gamma. 2010 Phytother Res pmid:20222152
Xiao C et al. Synthesis of methyl-substituted xanthotoxol to clarify prooxidant effect of methyl on radical-induced oxidation of DNA. 2010 Eur J Med Chem pmid:20332056
Li Z et al. Dual response surface-optimized synthesis of L-menthyl conjugated linoleate in solvent-free system by Candida rugosa lipase. 2010 Bioresour. Technol. pmid:19833506
Schwartz J et al. Dietary intake and plasma concentrations of PUFA and LC-PUFA in breastfed and formula fed infants under real-life conditions. 2010 Eur J Nutr pmid:19851802
Brodhun F et al. PpoC from Aspergillus nidulans is a fusion protein with only one active haem. 2010 Biochem. J. pmid:19878096
McKay DL et al. Chronic and acute effects of walnuts on antioxidant capacity and nutritional status in humans: a randomized, cross-over pilot study. 2010 Nutr J pmid:20462428
Rodrigues AS et al. Proton leak modulation in testicular mitochondria affects reactive oxygen species production and lipid peroxidation. 2010 Cell Biochem. Funct. pmid:20235330
Zabielski P et al. The effect of high-fat diet on the sphingolipid pathway of signal transduction in regenerating rat liver. 2010 Prostaglandins Other Lipid Mediat. pmid:20599517
Zengin G et al. In vitro antioxidant capacities and fatty acid compositions of three Centaurea species collected from Central Anatolia region of Turkey. 2010 Food Chem. Toxicol. pmid:20600531
Shen Q et al. Antioxidant activity in vitro of the selenium-contained protein from the Se-enriched Bifidobacterium animalis 01. 2010 Anaerobe pmid:20601030