| MeSH term | MeSH ID | Detail |
|---|---|---|
| Glioma | D005910 | 112 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Seizures | D012640 | 87 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
Linoleic acid
Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoleic acid?
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoleic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with Linoleic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoleic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Linoleic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoleic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sidransky H and Verney E | Toxic effect of valproic acid on tryptophan binding to rat hepatic nuclei. | 1996 | Toxicology | pmid:8619251 |
| DeMar JC et al. | Biosynthesis of the unsaturated 14-carbon fatty acids found on the N termini of photoreceptor-specific proteins. | 1996 | J. Biol. Chem. | pmid:8617777 |
| van Egmond AW et al. | Effect of linoleic acid intake on growth of infants with cystic fibrosis. | 1996 | Am. J. Clin. Nutr. | pmid:8615359 |
| Louheranta AM et al. | Linoleic acid intake and susceptibility of very-low-density and low density lipoproteins to oxidation in men. | 1996 | Am. J. Clin. Nutr. | pmid:8615351 |
| Ip C et al. | Effect of timing and duration of dietary conjugated linoleic acid on mammary cancer prevention. | 1995 | Nutr Cancer | pmid:8610043 |
| Yiin SJ and Lin TH | Lead-catalyzed peroxidation of essential unsaturated fatty acid. | 1995 | Biol Trace Elem Res | pmid:8605084 |
| Iwase H et al. | Superoxide anion reduces the ability of myeloperoxidase to damage lipids. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8605038 |
| Ogretmen B et al. | Effects of sodium saccharin and linoleic acid on mRNA levels of Her2/neu and p53 in a human breast epithelial cell line. | 1996 | Cancer Lett. | pmid:8603385 |
| Routi T et al. | Effects of prospective, randomized cholesterol-lowering dietary intervention and apolipoprotein E phenotype on serum lipoprotein(a) concentrations of infants aged 7-24 mo. | 1996 | Am. J. Clin. Nutr. | pmid:8602597 |
| Hennig B et al. | Linoleic acid activates nuclear transcription factor-kappa B (NF-kappa B) and induces NF-kappa B-dependent transcription in cultured endothelial cells. | 1996 | Am. J. Clin. Nutr. | pmid:8602587 |
| Aveldaño MI and Donnari D | Plasma phospholipid fatty acids in X-linked adrenoleukodystrophy. | 1996 | Clin. Chem. | pmid:8598113 |
| Guil JL et al. | Identification of fatty acids in edible wild plants by gas chromatography. | 1996 | J Chromatogr A | pmid:8589832 |
| Périchon R and Bourre JM | Peroxisomal beta-oxidation activity and catalase activity during development and aging in mouse liver. | 1995 | Biochimie | pmid:8589059 |
| Fuhrmann H and Sallmann HP | Alpha-tocopherol and phospholipase A2 in liver and brain of chicks posthatching: the influence of dietary fat and vitamin E. | 1995 | Ann. Nutr. Metab. | pmid:8585700 |
| Boscá F et al. | Evaluation of ketoprofen (R,S and R/S) phototoxicity by a battery of in vitro assays. | 1995 | J. Photochem. Photobiol. B, Biol. | pmid:8583281 |
| Ritenbaugh C et al. | Risk factors for Barrett's oesophagus: a life history approach to behavioural assessment in the distant past. | 1995 | Eur. J. Cancer Prev. | pmid:8580781 |
| Abdel Baset H et al. | Characterization of arachidonic-acid-metabolizing enzymes in adult Schistisoma mansoni. | 1995 | Mol. Biochem. Parasitol. | pmid:8577345 |
| Demmelmair H et al. | Estimation of arachidonic acid synthesis in full term neonates using natural variation of 13C content. | 1995 | J. Pediatr. Gastroenterol. Nutr. | pmid:8576811 |
| Ghusain-Choueiri AA and Rath EA | Effect of carbohydrate source on lipid metabolism in lactating mice and on pup development. | 1995 | Br. J. Nutr. | pmid:8562569 |
| Heiskanen K et al. | Interactions of cis-fatty acids and their anilides with formyl-methionyl-leucyl-phenylalanine, phorbol myristate acetate and dioctanoyl-s,n-glycerol in human leukocytes. | 1995 | Toxicology | pmid:8560489 |
| Luthria DL and Sprecher H | Metabolism of deuterium-labeled linoleic, 6,9,12-octadecatrienoic, 8,11,14-eicosatrienoic, and arachidonic acids in the rat. | 1995 | J. Lipid Res. | pmid:8558078 |
| Bauldry SA et al. | Activation of cytosolic phospholipase A2 in permeabilized human neutrophils. | 1996 | Biochim. Biophys. Acta | pmid:8555268 |
| Mirzoeva OK et al. | Competitive inhibition of the 5-lipoxygenase-catalysed linoleate oxidation by arachidonic and 5-hydroperoxy-eicosatetraenoic acids. | 1995 | FEBS Lett. | pmid:8549743 |
| Ivanetich KM et al. | Delta 6-desaturase: improved methodology and analysis of the kinetics in a multi-enzyme system. | 1996 | Biochim. Biophys. Acta | pmid:8547334 |
| Siguel EN and Lerman RH | Prevalence of essential fatty acid deficiency in patients with chronic gastrointestinal disorders. | 1996 | Metab. Clin. Exp. | pmid:8544768 |
| Antras-Ferry J et al. | Fatty acids and fibrates are potent inducers of transcription of the phosphenolpyruvate carboxykinase gene in adipocytes. | 1995 | Eur. J. Biochem. | pmid:8536680 |
| Groves BA | Exit linoleic acid too? | 1996 | Lancet | pmid:8531562 |
| Wiseman SA et al. | Comparison of the effects of dietary vitamin E on in vivo and in vitro parameters of lipid peroxidation in the rabbit. | 1995 | Free Radic. Biol. Med. | pmid:8529921 |
| Shen J et al. | Transgenic rabbits with the integrated human 15-lipoxygenase gene driven by a lysozyme promoter: macrophage-specific expression and variable positional specificity of the transgenic enzyme. | 1995 | FASEB J. | pmid:8529842 |
| Abushufa R et al. | Essential fatty acid status in patients on long-term home parenteral nutrition. | 1995 Jul-Aug | JPEN J Parenter Enteral Nutr | pmid:8523627 |
| Arnhold J et al. | The action of hypochlorous acid on phosphatidylcholine liposomes in dependence on the content of double bonds. Stoichiometry and NMR analysis. | 1995 | Chem. Phys. Lipids | pmid:8521532 |
| Nishio H and Mori K | Reinvestigation of the structure of the esterified cerebroside in the epidermis of guinea pigs. | 1995 | Biosci. Biotechnol. Biochem. | pmid:8520108 |
| Osawa T et al. | Antioxidative activity of tetrahydrocurcuminoids. | 1995 | Biosci. Biotechnol. Biochem. | pmid:8520105 |
| Hudson EA et al. | Kinetics of the inhibition of tumour growth in mice by eicosapentaenoic acid-reversal by linoleic acid. | 1993 | Biochem. Pharmacol. | pmid:8517859 |
| Thompson RL et al. | Cigarette smoking, polyunsaturated fats, and coronary heart disease. | 1993 | Ann. N. Y. Acad. Sci. | pmid:8512244 |
| Wey HE et al. | Essential fatty acid deficiency in cultured human keratinocytes attenuates toxicity due to lipid peroxidation. | 1993 | Toxicol. Appl. Pharmacol. | pmid:8511784 |
| Naval J et al. | Alternative route for the biosynthesis of polyunsaturated fatty acids in K562 cells. | 1993 | Biochem. J. | pmid:8489510 |
| Bafor M et al. | Biosynthesis of vernoleate (cis-12-epoxyoctadeca-cis-9-enoate) in microsomal preparations from developing endosperm of Euphorbia lagascae. | 1993 | Arch. Biochem. Biophys. | pmid:8489257 |
| Sugano M and Koba K | Dietary protein and lipid metabolism: a multifunctional effect. | 1993 | Ann. N. Y. Acad. Sci. | pmid:8489133 |
| Püttmann M et al. | Fast HPLC determination of serum free fatty acids in the picomole range. | 1993 | Clin. Chem. | pmid:8485873 |
| Lomnitski L et al. | The interaction between beta-carotene and lipoxygenase in plant and animal systems. | 1993 | Biochim. Biophys. Acta | pmid:8481396 |
| van Haaster CM et al. | Formation of prostanoids and hydroxy fatty acids by stimulated peritoneal mast cells: role of the dietary fat type in rat. | 1993 | Biochim. Biophys. Acta | pmid:8466942 |
| Lecerf J et al. | Variations in the fatty acid composition of lipid classes from lipoproteins in elderly women. | 1993 | Atherosclerosis | pmid:8457263 |
| Vaughan PF et al. | Effect of inhibitors of eicosanoid metabolism on release of [3H]noradrenaline from the human neuroblastoma, SH-SY5Y. | 1993 | J. Neurochem. | pmid:8455030 |
| Band AM et al. | The mechanism of arachidonic acid-induced insulin secretion from rat islets of Langerhans. | 1993 | Biochim. Biophys. Acta | pmid:8452880 |
| Oliw EH | bis-Allylic hydroxylation of linoleic acid and arachidonic acid by human hepatic monooxygenases. | 1993 | Biochim. Biophys. Acta | pmid:8443245 |
| Batna A et al. | The occurrence of furan fatty acids in Isochrysis sp. and Phaeodactylum tricornutum. | 1993 | Biochim. Biophys. Acta | pmid:8443233 |
| Terada N et al. | Definition of the roles for iron and essential fatty acids in cell cycle progression of normal human T lymphocytes. | 1993 | Exp. Cell Res. | pmid:8440323 |
| Jones AL et al. | Temperature-induced membrane-lipid adaptation in Acanthamoeba castellanii. | 1993 | Biochem. J. | pmid:8439295 |
| Abbey M et al. | Oxidation of low-density lipoproteins: intraindividual variability and the effect of dietary linoleate supplementation. | 1993 | Am. J. Clin. Nutr. | pmid:8438773 |