| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hyperpigmentation | D017495 | 11 associated lipids |
| Dermatitis, Allergic Contact | D017449 | 20 associated lipids |
| Hypertrophy, Left Ventricular | D017379 | 12 associated lipids |
| Endometrial Neoplasms | D016889 | 30 associated lipids |
| Helicobacter Infections | D016481 | 21 associated lipids |
| Mammary Neoplasms, Animal | D015674 | 27 associated lipids |
| Weight Loss | D015431 | 56 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Vitamin E Deficiency | D014811 | 29 associated lipids |
| Vitamin D Deficiency | D014808 | 13 associated lipids |
Linoleic acid
Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoleic acid?
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoleic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with Linoleic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoleic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoleic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoleic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Alsaidan M et al. | Cells to Surgery Quiz: July 2015. | 2015 | J. Invest. Dermatol. | pmid:26066894 |
| Schumann T et al. | Deregulation of PPARβ/δ target genes in tumor-associated macrophages by fatty acid ligands in the ovarian cancer microenvironment. | 2015 | Oncotarget | pmid:25968567 |
| Salazar MO et al. | A thin-layer chromatography autographic method for the detection of inhibitors of the Salmonella PhoP-PhoQ regulatory system. | 2014 Mar-Apr | Phytochem Anal | pmid:24185747 |
| Song E et al. | Deamidated lipocalin-2 induces endothelial dysfunction and hypertension in dietary obese mice. | 2014 | J Am Heart Assoc | pmid:24721803 |
| Reed S et al. | Dietary zinc deficiency affects blood linoleic acid: dihomo-γ-linolenic acid (LA:DGLA) ratio; a sensitive physiological marker of zinc status in vivo (Gallus gallus). | 2014 | Nutrients | pmid:24658588 |
| Armstrong EH et al. | Structural basis for ligand regulation of the fatty acid-binding protein 5, peroxisome proliferator-activated receptor β/δ (FABP5-PPARβ/δ) signaling pathway. | 2014 | J. Biol. Chem. | pmid:24692551 |
| Hodson L et al. | Plasma and erythrocyte fatty acids reflect intakes of saturated and n-6 PUFA within a similar time frame. | 2014 | J. Nutr. | pmid:24225449 |
| Ebrahimi M et al. | Effects of oils rich in linoleic and α-linolenic acids on fatty acid profile and gene expression in goat meat. | 2014 | Nutrients | pmid:25255382 |
| Xu QY et al. | Metabolomic analysis of simvastatin and fenofibrate intervention in high-lipid diet-induced hyperlipidemia rats. | 2014 | Acta Pharmacol. Sin. | pmid:25220639 |
| Buehlmann C et al. | Desert ants locate food by combining high sensitivity to food odors with extensive crosswind runs. | 2014 | Curr. Biol. | pmid:24726153 |
| BuÄek A et al. | Δ12-Fatty acid desaturase from Candida parapsilosis is a multifunctional desaturase producing a range of polyunsaturated and hydroxylated fatty acids. | 2014 | PLoS ONE | pmid:24681902 |
| Nadtochiy SM et al. | Mitochondrially targeted nitro-linoleate: a new tool for the study of cardioprotection. | 2014 | Br. J. Pharmacol. | pmid:24102583 |
| Arfaoui MO et al. | Variation in oil content, fatty acid and phytosterols profile of Onopordum acanthium L. during seed development. | 2014 | Nat. Prod. Res. | pmid:25103576 |
| Wright CR and Setzer WN | Chemical composition of volatiles from Opuntia littoralis, Opuntia ficus-indica, and Opuntia prolifera growing on Catalina Island, California. | 2014 | Nat. Prod. Res. | pmid:24354326 |
| Radice M et al. | Chemical characterization and antioxidant activity of Amazonian (Ecuador) Caryodendron orinocense Karst. and Bactris gasipaes Kunth seed oils. | 2014 | J Oleo Sci | pmid:25391685 |
| Yang Q et al. | Anti-thrombotic effects of α-linolenic acid isolated from Zanthoxylum bungeanum Maxim seeds. | 2014 | BMC Complement Altern Med | pmid:25252789 |
| Shimizu N et al. | De novo biosynthesis of linoleic acid and its conversion to the hydrocarbon (Z,Z)-6,9-heptadecadiene in the astigmatid mite, Carpoglyphus lactis: incorporation experiments with 13C-labeled glucose. | 2014 | Insect Biochem. Mol. Biol. | pmid:24333472 |
| Hoffman LC et al. | Lipid and protein stability and sensory evaluation of ostrich (Struthio camelus) droëwors with the addition of rooibos tea extract (Aspalathus linearis) as a natural antioxidant. | 2014 | Meat Sci. | pmid:24334052 |
| Breiden B and Sandhoff K | The role of sphingolipid metabolism in cutaneous permeability barrier formation. | 2014 | Biochim. Biophys. Acta | pmid:23954553 |
| Mahendran Y et al. | Association of erythrocyte membrane fatty acids with changes in glycemia and risk of type 2 diabetes. | 2014 | Am. J. Clin. Nutr. | pmid:24153340 |