| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hyperpigmentation | D017495 | 11 associated lipids |
| Dermatitis, Allergic Contact | D017449 | 20 associated lipids |
| Hypertrophy, Left Ventricular | D017379 | 12 associated lipids |
| Endometrial Neoplasms | D016889 | 30 associated lipids |
| Helicobacter Infections | D016481 | 21 associated lipids |
| Mammary Neoplasms, Animal | D015674 | 27 associated lipids |
| Weight Loss | D015431 | 56 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Vitamin E Deficiency | D014811 | 29 associated lipids |
| Vitamin D Deficiency | D014808 | 13 associated lipids |
Linoleic acid
Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoleic acid?
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoleic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with Linoleic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoleic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoleic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoleic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Horrobin DF | Essential fatty acid metabolism and its modification in atopic eczema. | 2000 | Am. J. Clin. Nutr. | pmid:10617999 |
| Connolly JM et al. | Effects of reduced dietary linoleic acid intake, alone or combined with an algal source of docosahexaenoic acid, on MDA-MB-231 breast cancer cell growth and apoptosis in nude mice. | 1999 | Nutr Cancer | pmid:10624705 |
| Salo P et al. | Low-saturated fat, low-cholesterol diet in 3-year-old children: effect on intake and composition of trans fatty acids and other fatty acids in serum phospholipid fraction-The STRIP study. Special Turku coronary Risk factor Intervention Project for children. | 2000 | J. Pediatr. | pmid:10636973 |
| Oriani G et al. | Effects of intramuscular injection of alpha-tocopheryl acetate on fatty acid profile in lamb liver. | 1999 | Int J Vitam Nutr Res | pmid:10642895 |
| de Deckere EA et al. | Effects of conjugated linoleic acid (CLA) isomers on lipid levels and peroxisome proliferation in the hamster. | 1999 | Br. J. Nutr. | pmid:10655980 |
| Berghaus TM et al. | Essential fatty acids and their long-chain polyunsaturated metabolites in maternal and cord plasma triglycerides during late gestation. | 2000 | Biol. Neonate | pmid:10657686 |
| Rukkwamsuk T et al. | Interrelation of fatty acid composition in adipose tissue, serum, and liver of dairy cows during the development of fatty liver postpartum. | 2000 | J. Dairy Sci. | pmid:10659963 |
| Heeley EL et al. | Phospholipid molecular species of bronchoalveolar lavage fluid after local allergen challenge in asthma. | 2000 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:10666114 |
| Grobas S et al. | Influence of dietary energy, supplemental fat and linoleic acid concentration on performance of laying hens at two ages. | 1999 | Br. Poult. Sci. | pmid:10670682 |
| Larqué E et al. | Dietary trans fatty acids affect docosahexaenoic acid concentrations in plasma and liver but not brain of pregnant and fetal rats. | 2000 | Pediatr. Res. | pmid:10674359 |
| Jarmuszkiewicz W et al. | First evidence and characterization of an uncoupling protein in fungi kingdom: CpUCP of Candida parapsilosis. | 2000 | FEBS Lett. | pmid:10675527 |
| Rüttinger HH and Radschuweit A | Determination of peroxides by capillary zone electrophoresis with amperometric detection. | 2000 | J Chromatogr A | pmid:10677087 |
| Sébédio JL et al. | Recent advances in conjugated linoleic acid research. | 1999 | Curr Opin Clin Nutr Metab Care | pmid:10678680 |
| Saito A et al. | Effects of capsaicin on biliary free fatty acids in rats. | 2000 | Int J Vitam Nutr Res | pmid:10683757 |
| López-Nicolás JM et al. | Effect of calcium on the oxidation of linoleic acid by potato (Solanum tuberosum var. Desiree) tuber 5-lipoxygenase. | 2000 | J. Agric. Food Chem. | pmid:10691630 |
| Sekiwa Y et al. | Isolation of novel glucosides related to gingerdiol from ginger and their antioxidative activities. | 2000 | J. Agric. Food Chem. | pmid:10691642 |
| Kim D and Pleumsamran A | Cytoplasmic unsaturated free fatty acids inhibit ATP-dependent gating of the G protein-gated K(+) channel. | 2000 | J. Gen. Physiol. | pmid:10694258 |
| Shimada A et al. | Phytotoxicity of indole-3-acetic acid produced by the fungus, Pythium aphanidermatum. | 2000 | Biosci. Biotechnol. Biochem. | pmid:10705467 |
| Kitts DD et al. | Antioxidant activity of the flaxseed lignan secoisolariciresinol diglycoside and its mammalian lignan metabolites enterodiol and enterolactone. | 1999 | Mol. Cell. Biochem. | pmid:10705999 |
| Cox JE et al. | Suppression of food intake, body weight, and body fat by jejunal fatty acid infusions. | 2000 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:10712279 |