| MeSH term | MeSH ID | Detail |
|---|---|---|
| Heart Failure | D006333 | 36 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Hyperlipidemia, Familial Combined | D006950 | 9 associated lipids |
| Hypersensitivity, Immediate | D006969 | 14 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
| Hypertension, Renal | D006977 | 9 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Kidney Diseases | D007674 | 29 associated lipids |
| Polycystic Kidney Diseases | D007690 | 12 associated lipids |
| Lactose Intolerance | D007787 | 2 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Lipid Metabolism, Inborn Errors | D008052 | 26 associated lipids |
| Liver Diseases | D008107 | 31 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Lymphopenia | D008231 | 2 associated lipids |
| Malabsorption Syndromes | D008286 | 16 associated lipids |
| Melanosis | D008548 | 4 associated lipids |
Linoleic acid
Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoleic acid?
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoleic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with Linoleic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoleic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoleic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoleic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Brush MG et al. | Abnormal essential fatty acid levels in plasma of women with premenstrual syndrome. | 1984 | Am. J. Obstet. Gynecol. | pmid:6091462 |
| Dworkin RH et al. | Linoleic acid and multiple sclerosis: a reanalysis of three double-blind trials. | 1984 | Neurology | pmid:6387534 |
| Chen TC et al. | Modulation of 1,25-dihydroxyvitamin D3 receptor by phospholipids and fatty acids. | 1984 | J. Lipid Res. | pmid:6099395 |
| Benaim G et al. | Different conformational states of the purified Ca2+-ATPase of the erythrocyte plasma membrane revealed by controlled trypsin proteolysis. | 1984 | J. Biol. Chem. | pmid:6234313 |
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| Manku MS et al. | Essential fatty acids in the plasma phospholipids of patients with atopic eczema. | 1984 | Br. J. Dermatol. | pmid:6329254 |
| Schick PK et al. | Arachidonate synthesis and uptake in isolated guinea-pig megakaryocytes and platelets. | 1984 | Biochim. Biophys. Acta | pmid:6433984 |
| Furukawa M et al. | Studies on arachidonate 5-lipoxygenase of rat basophilic leukemia cells. | 1984 | Biochim. Biophys. Acta | pmid:6089906 |
| Inouye S | Site-specific cleavage of double-strand DNA by hydroperoxide of linoleic acid. | 1984 | FEBS Lett. | pmid:6430718 |
| Ramesha CS and Thompson GA | The mechanism of membrane response to chilling. Effect of temperature on phospholipid deacylation and reacylation reactions in the cell surface membrane. | 1984 | J. Biol. Chem. | pmid:6430890 |
| Kitagawa S et al. | Activation of bovine platelets induced by long-chain unsaturated fatty acids at just below their lytic concentrations, and its mechanism. | 1984 | Biochim. Biophys. Acta | pmid:6435686 |
| Becker W | Distribution of 14C after oral administration of [1-14C]linoleic acid in rats fed different levels of essential fatty acids. | 1984 | J. Nutr. | pmid:6470826 |
| Rogiers V et al. | Abnormal fatty acid turnover in the phospholipids of the red blood cell membranes of cystic fibrosis patients (in vitro study). | 1984 | Pediatr. Res. | pmid:6472942 |
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| Hagve TA and Christophersen BO | Effect of dietary fats on arachidonic acid and eicosapentaenoic acid biosynthesis and conversion to C22 fatty acids in isolated rat liver cells. | 1984 | Biochim. Biophys. Acta | pmid:6093889 |
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| Buchanan MR et al. | 13-Hydroxyoctadecadienoic acid is the vessel wall chemorepellant factor, LOX. | 1985 | J. Biol. Chem. | pmid:3934168 |
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| Charnock JS et al. | Changes in fatty acid composition of the cardiac phospholipids of the cotton-eared marmoset (Callithrix jacchus) after feeding different lipid supplements. | 1985 | Ann. Nutr. Metab. | pmid:3922279 |
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| Reid JC and Husbands DR | Oxidative metabolism of long-chain fatty acids in mitochondria from sheep and rat liver. Evidence that sheep conserve linoleate by limiting its oxidation. | 1985 | Biochem. J. | pmid:3977825 |
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