Linoleic acid

Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.

Cross Reference

Introduction

To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoleic acid?

Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoleic acid

MeSH term MeSH ID Detail
Tuberculosis D014376 20 associated lipids
Thrombosis D013927 49 associated lipids
Stomach Neoplasms D013274 24 associated lipids
Staphylococcal Skin Infections D013207 9 associated lipids
Spirochaetales Infections D013145 2 associated lipids
Seizures D012640 87 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Pregnancy Complications, Neoplastic D011252 4 associated lipids
Precancerous Conditions D011230 48 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
Pneumonia, Viral D011024 3 associated lipids
Exocrine Pancreatic Insufficiency D010188 6 associated lipids
Pain D010146 64 associated lipids
Otitis Externa D010032 8 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Melanosis D008548 4 associated lipids
Malabsorption Syndromes D008286 16 associated lipids
Lymphopenia D008231 2 associated lipids
Lung Neoplasms D008175 171 associated lipids
Liver Diseases D008107 31 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoleic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with Linoleic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoleic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoleic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoleic acid

Download all related citations
Per page 10 20 50 100 | Total 4513
Authors Title Published Journal PubMed Link
Krizhanovskii C et al. EndoC-βH1 cells display increased sensitivity to sodium palmitate when cultured in DMEM/F12 medium. 2017 Islets pmid:28277987
Bentrad N et al. Identification and evaluation of antibacterial agents present in lipophilic fractions isolated from sub-products of Phoenix dactilyfera. 2017 Nat. Prod. Res. pmid:28403631
Zhou Y et al. UCP2 attenuates apoptosis of tubular epithelial cells in renal ischemia-reperfusion injury. 2017 Am. J. Physiol. Renal Physiol. pmid:28424210
Du H et al. Extraction and the Fatty Acid Profile of Rosa acicularis Seed Oil. 2017 J Oleo Sci pmid:29129896
Teh SS et al. Recovery and Utilization of Palm Oil Mill Effluent Source as Value-Added Food Products. 2017 J Oleo Sci pmid:29093377
Zhao A et al. Use of real-time cellular analysis and Plackett-Burman design to develop the serum-free media for PC-3 prostate cancer cells. 2017 PLoS ONE pmid:28945791
Qian J et al. Agonist-induced activation of human FFA1 receptor signals to extracellular signal-regulated kinase 1 and 2 through Gq- and Gi-coupled signaling cascades. 2017 Cell. Mol. Biol. Lett. pmid:28747926
Kim H et al. Association between maternal intake of n-6 to n-3 fatty acid ratio during pregnancy and infant neurodevelopment at 6 months of age: results of the MOCEH cohort study. 2017 Nutr J pmid:28420388
Cocchi M et al. Linoleic acid: Is this the key that unlocks the quantum brain? Insights linking broken symmetries in molecular biology, mood disorders and personalistic emergentism. 2017 BMC Neurosci pmid:28420346
Sinanoglou VJ et al. Factors affecting human colostrum fatty acid profile: A case study. 2017 PLoS ONE pmid:28410426
Buckley MT et al. Selection in Europeans on Fatty Acid Desaturases Associated with Dietary Changes. 2017 Mol. Biol. Evol. pmid:28333262
Tiburcio TC et al. Connexin32 deficiency is associated with liver injury, inflammation and oxidative stress in experimental non-alcoholic steatohepatitis. 2017 Clin. Exp. Pharmacol. Physiol. pmid:27859493
Jory J Abnormal fatty acids in Canadian children with autism. 2016 Nutrition pmid:26746679
Yen HW et al. Cultivation of oleaginous Rhodotorula mucilaginosa in airlift bioreactor by using seawater. 2016 J. Biosci. Bioeng. pmid:26319611
Shapiro H et al. Beyond the classic eicosanoids: Peripherally-acting oxygenated metabolites of polyunsaturated fatty acids mediate pain associated with tissue injury and inflammation. 2016 Prostaglandins Leukot. Essent. Fatty Acids pmid:27067460
Bradley RM et al. Influence of tissue, diet, and enzymatic remodeling on cardiolipin fatty acyl profile. 2016 Mol Nutr Food Res pmid:27061349
Chiba T et al. The Precise Structures and Stereochemistry of Trihydroxy-linoleates Esterified in Human and Porcine Epidermis and Their Significance in Skin Barrier Function: IMPLICATION OF AN EPOXIDE HYDROLASE IN THE TRANSFORMATIONS OF LINOLEATE. 2016 J. Biol. Chem. pmid:27151221
Jumbe T et al. Whole Blood Levels of the n-6 Essential Fatty Acid Linoleic Acid Are Inversely Associated with Stunting in 2-to-6 Year Old Tanzanian Children: A Cross-Sectional Study. 2016 PLoS ONE pmid:27137223
McNamara RK and Welge JA Meta-analysis of erythrocyte polyunsaturated fatty acid biostatus in bipolar disorder. 2016 Bipolar Disord pmid:27087497
Ramsden CE et al. Re-evaluation of the traditional diet-heart hypothesis: analysis of recovered data from Minnesota Coronary Experiment (1968-73). 2016 BMJ pmid:27071971