Linoleic acid

Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.

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Introduction

To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoleic acid?

Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoleic acid

PubChem Associated disorders and diseases

What pathways are associated with Linoleic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with Linoleic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoleic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoleic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoleic acid

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Authors Title Published Journal PubMed Link
Phan CW et al. Uridine from Pleurotus giganteus and Its Neurite Outgrowth Stimulatory Effects with Underlying Mechanism. 2015 PLoS ONE pmid:26565787
Rondanelli M et al. Effects of two-months balanced diet in metabolically healthy obesity: lipid correlations with gender and BMI-related differences. 2015 Lipids Health Dis pmid:26511930
Turci F et al. Free-radical chemistry as a means to evaluate lunar dust health hazard in view of future missions to the moon. 2015 Astrobiology pmid:25946080
Dahlhoff M et al. EGFR/ERBB receptors differentially modulate sebaceous lipogenesis. 2015 FEBS Lett. pmid:25889637
Gouveia-Figueira S et al. Serum levels of oxylipins in achilles tendinopathy: an exploratory study. 2015 PLoS ONE pmid:25875933
Vlachogianni IC et al. In vitro assessment of antioxidant activity of tyrosol, resveratrol and their acetylated derivatives. 2015 Food Chem pmid:25660873
Perumalsamy H et al. Larvicidal activity and possible mode of action of four flavonoids and two fatty acids identified in Millettia pinnata seed toward three mosquito species. 2015 Parasit Vectors pmid:25928224
Nakahashi H et al. Evaluation of the Key Odorants in Volatile Oils from Tubers of Apios americana Medikus. 2015 J Oleo Sci pmid:26521814
Naughton SS et al. Australia's nutrition transition 1961-2009: a focus on fats. 2015 Br. J. Nutr. pmid:26123446
Yildiztekin F et al. Antioxidant, anticholinesterase and tyrosinase inhibition activities, and fatty acids of Crocus mathewii - A forgotten endemic angiosperm of Turkey. 2016 Pharm Biol pmid:26810584
Ma C et al. NAFLD causes selective CD4(+) T lymphocyte loss and promotes hepatocarcinogenesis. 2016 Nature pmid:26934227
Padayachee T et al. The Detection of Metabolite-Mediated Gene Module Co-Expression Using Multivariate Linear Models. 2016 PLoS ONE pmid:26918614
Hellström F et al. Association between plasma concentrations of linoleic acid-derived oxylipins and the perceived pain scores in an exploratory study in women with chronic neck pain. 2016 BMC Musculoskelet Disord pmid:26916287
Ripoll-Rozada J et al. Type IV traffic ATPase TrwD as molecular target to inhibit bacterial conjugation. 2016 Mol. Microbiol. pmid:26915347
Harris WS et al. Red Blood Cell Fatty Acids and Incident Diabetes Mellitus in the Women's Health Initiative Memory Study. 2016 PLoS ONE pmid:26881936
Puebla C et al. Linoleic acid permeabilizes gastric epithelial cells by increasing connexin 43 levels in the cell membrane via a GPR40- and Akt-dependent mechanism. 2016 Biochim. Biophys. Acta pmid:26869446
Yuan H et al. A network based covariance test for detecting multivariate eQTL in saccharomyces cerevisiae. 2016 BMC Syst Biol pmid:26818242
Matravadia S et al. LA and ALA prevent glucose intolerance in obese male rats without reducing reactive lipid content, but cause tissue-specific changes in fatty acid composition. 2016 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:26764053
Ito J et al. A novel chiral stationary phase HPLC-MS/MS method to discriminate between enzymatic oxidation and auto-oxidation of phosphatidylcholine. 2016 Anal Bioanal Chem pmid:27549797
Jory J Abnormal fatty acids in Canadian children with autism. 2016 Nutrition pmid:26746679
Xie P et al. Metabonomic Study of Biochemical Changes in Human Hair of Heroin Abusers by Liquid Chromatography Coupled with Ion Trap-Time of Flight Mass Spectrometry. 2016 J. Mol. Neurosci. pmid:26445826
DoÄŸru-Koca A et al. Chemotaxonomic perspectives of the Paracaryum (Cynoglosseae, Boraginaceae) taxa based on fruit fatty acid composition. 2016 Phytochemistry pmid:27600716
Troche JR et al. Alcohol Consumption-Related Metabolites in Relation to Colorectal Cancer and Adenoma: Two Case-Control Studies Using Serum Biomarkers. 2016 PLoS ONE pmid:26967509
Yen HW et al. Cultivation of oleaginous Rhodotorula mucilaginosa in airlift bioreactor by using seawater. 2016 J. Biosci. Bioeng. pmid:26319611
Medema S et al. Levels of Red Blood Cell Fatty Acids in Patients With Psychosis, Their Unaffected Siblings, and Healthy Controls. 2016 Schizophr Bull pmid:26385764
Valdez-Morales M et al. Phenolic Compounds, Antioxidant Activity and Lipid Profile of Huitlacoche Mushroom (Ustilago maydis) Produced in Several Maize Genotypes at Different Stages of Development. 2016 Plant Foods Hum Nutr pmid:27605221
Shapiro H et al. Beyond the classic eicosanoids: Peripherally-acting oxygenated metabolites of polyunsaturated fatty acids mediate pain associated with tissue injury and inflammation. 2016 Prostaglandins Leukot. Essent. Fatty Acids pmid:27067460
Jablonická V et al. Identification of a secretory phospholipase A2 from Papaver somniferum L. that transforms membrane phospholipids. 2016 Phytochemistry pmid:27473012
Arnold WR et al. Asymmetric Binding and Metabolism of Polyunsaturated Fatty Acids (PUFAs) by CYP2J2 Epoxygenase. 2016 Biochemistry pmid:27992998
Montaño A et al. Fatty Acid and Phenolic Compound Concentrations in Eight Different Monovarietal Virgin Olive Oils from Extremadura and the Relationship with Oxidative Stability. 2016 Int J Mol Sci pmid:27886101
Zhao Z et al. The Association of Fatty Acid Levels and Gleason Grade among Men Undergoing Radical Prostatectomy. 2016 PLoS ONE pmid:27880795
Takabe W et al. Esterification of 24S-OHC induces formation of atypical lipid droplet-like structures, leading to neuronal cell death. 2016 J. Lipid Res. pmid:27647838
Zhang YH et al. The Use of Gene Ontology Term and KEGG Pathway Enrichment for Analysis of Drug Half-Life. 2016 PLoS ONE pmid:27780226
Rodrigues HG et al. Oral Administration of Linoleic Acid Induces New Vessel Formation and Improves Skin Wound Healing in Diabetic Rats. 2016 PLoS ONE pmid:27764229
Kojima K et al. A simple method for isolation and construction of markerless cyanobacterial mutants defective in acyl-acyl carrier protein synthetase. 2016 Appl. Microbiol. Biotechnol. pmid:27704180
Ishida K and Jolly ER Hsp70 May Be a Molecular Regulator of Schistosome Host Invasion. 2016 PLoS Negl Trop Dis pmid:27611863
Venäläinen TM et al. Effect of a 2-y dietary and physical activity intervention on plasma fatty acid composition and estimated desaturase and elongase activities in children: the Physical Activity and Nutrition in Children Study. 2016 Am. J. Clin. Nutr. pmid:27581473
Sakayori N et al. Maternal Nutritional Imbalance between Linoleic Acid and Alpha-Linolenic Acid Increases Offspring's Anxious Behavior with a Sex-Dependent Manner in Mice. 2016 Tohoku J. Exp. Med. pmid:27558477
Karupaiah T et al. Comparing effects of soybean oil- and palm olein-based mayonnaise consumption on the plasma lipid and lipoprotein profiles in human subjects: a double-blind randomized controlled trial with cross-over design. 2016 Lipids Health Dis pmid:27535127
Raimondi S et al. Conjugated Linoleic Acid Production by Bifidobacteria: Screening, Kinetic, and Composition. 2016 Biomed Res Int pmid:27429985
Green D et al. Central activation of TRPV1 and TRPA1 by novel endogenous agonists contributes to mechanical allodynia and thermal hyperalgesia after burn injury. 2016 Mol Pain pmid:27411353
Castrejón-Tellez V et al. The Effect of Resveratrol and Quercetin Treatment on PPAR Mediated Uncoupling Protein (UCP-) 1, 2, and 3 Expression in Visceral White Adipose Tissue from Metabolic Syndrome Rats. 2016 Int J Mol Sci pmid:27399675
Zhao J et al. Dietary fat intake and endometrial cancer risk: A dose response meta-analysis. 2016 Medicine (Baltimore) pmid:27399120
Bradley RM et al. Influence of tissue, diet, and enzymatic remodeling on cardiolipin fatty acyl profile. 2016 Mol Nutr Food Res pmid:27061349
Wood MH et al. Comparative Adsorption of Saturated and Unsaturated Fatty Acids at the Iron Oxide/Oil Interface. 2016 Langmuir pmid:26707597
Wang JJ et al. Two ω-3 FADs Are Associated with Peach Fruit Volatile Formation. 2016 Int J Mol Sci pmid:27043529
Ramsden CE et al. Dietary linoleic acid-induced alterations in pro- and anti-nociceptive lipid autacoids: Implications for idiopathic pain syndromes? 2016 Mol Pain pmid:27030719
Domenichiello AF et al. The effect of linoleic acid on the whole body synthesis rates of polyunsaturated fatty acids from α-linolenic acid and linoleic acid in free-living rats. 2016 J. Nutr. Biochem. pmid:27012633
Yary T et al. Serum n-6 polyunsaturated fatty acids, Δ5- and Δ6-desaturase activities, and risk of incident type 2 diabetes in men: the Kuopio Ischaemic Heart Disease Risk Factor Study. 2016 Am. J. Clin. Nutr. pmid:27009754
Abdullah BM et al. Polyesters Based on Linoleic Acid for Biolubricant Basestocks: Low-Temperature, Tribological and Rheological Properties. 2016 PLoS ONE pmid:27008312