Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Batna A et al. | Lipid peroxidation in presence of ebselen. | 1997 | Chem. Phys. Lipids | pmid:9275309 |
Fabritius D et al. | Biotransformation of linoleic acid with the Candida tropicalis M25 mutant. | 1997 | Appl. Microbiol. Biotechnol. | pmid:9274051 |
Lopez Jimenez JA et al. | Linoleic acid metabolism in primary cultures of adult rat cardiomyocytes is impaired by aging. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9266846 |
Jenkins TC | Ruminal fermentation and nutrient digestion in sheep fed hydroxyethylsoyamide. | 1997 | J. Anim. Sci. | pmid:9263076 |
Feussner I et al. | Structural elucidation of oxygenated storage lipids in cucumber cotyledons. Implication of lipid body lipoxygenase in lipid mobilization during germination. | 1997 | J. Biol. Chem. | pmid:9261186 |
Badart-Smook A et al. | Fetal growth is associated positively with maternal intake of riboflavin and negatively with maternal intake of linoleic acid. | 1997 | J Am Diet Assoc | pmid:9259708 |
Bakker N et al. | Adipose fatty acids and cancers of the breast, prostate and colon: an ecological study. EURAMIC Study Group. | 1997 | Int. J. Cancer | pmid:9259395 |
Risé P et al. | Effects of simvastatin on the metabolism of polyunsaturated fatty acids and on glycerolipid, cholesterol, and de novo lipid synthesis in THP-1 cells. | 1997 | J. Lipid Res. | pmid:9254057 |
Castelli F et al. | Dipalmitoylphosphatidylcholine/linoleic acid mixed unilamellar vesicles as model membranes for studies on novel free-radical scavengers. | 1997 | J Pharmacol Toxicol Methods | pmid:9253749 |
Siguel E | Essential fatty acid status in patients. | 1997 Jul-Aug | JPEN J Parenter Enteral Nutr | pmid:9252955 |
Howlett NG and Avery SV | Induction of lipid peroxidation during heavy metal stress in Saccharomyces cerevisiae and influence of plasma membrane fatty acid unsaturation. | 1997 | Appl. Environ. Microbiol. | pmid:9251184 |
Parmentier HK et al. | Dietary unsaturated fatty acids affect antibody responses and growth of chickens divergently selected for humoral responses to sheep red blood cells. | 1997 | Poult. Sci. | pmid:9251147 |
Bosca F et al. | Photophysical and photochemical characterization of a photosensitizing drug: a combined steady state photolysis and laser flash photolysis study on carprofen. | 1997 | Chem. Res. Toxicol. | pmid:9250417 |
Thomson AB et al. | Nutrient uptake into undifferentiated and differentiated HT-29 cells in culture. | 1997 | Can. J. Physiol. Pharmacol. | pmid:9250367 |
Hannah JS et al. | High fat, high cholesterol diets alter low density lipoprotein size and binding affinity in monkeys. | 1997 | Atherosclerosis | pmid:9247355 |
Lanson M et al. | Supplementation of MCF-7 cells with essential fatty acids induces the activation of protein kinase C in response to IGF-1. | 1997 | J Lipid Mediat Cell Signal | pmid:9246607 |
Haraguchi H et al. | Antioxidative action of diterpenoids from Podocarpus nagi. | 1997 | Planta Med. | pmid:9225601 |
Shi F et al. | Permeability and metabolic properties of a trophoblast cell line (HRP-1) derived from normal rat placenta. | 1997 | Exp. Cell Res. | pmid:9223380 |
Quoc KP and Dubacq JP | Effect of growth temperature on the biosynthesis of eukaryotic lipid molecular species by the cyanobacterium Spirulina platensis. | 1997 | Biochim. Biophys. Acta | pmid:9219908 |
Jira W et al. | Increased levels of lipid oxidation products in low density lipoproteins of patients suffering from rheumatoid arthritis. | 1997 | Chem. Phys. Lipids | pmid:9219348 |