Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Liu Y and Roth JP | A Revised Mechanism for Human Cyclooxygenase-2. | 2016 | J. Biol. Chem. | pmid:26565028 |
Medema S et al. | Levels of Red Blood Cell Fatty Acids in Patients With Psychosis, Their Unaffected Siblings, and Healthy Controls. | 2016 | Schizophr Bull | pmid:26385764 |
Stewart CJ et al. | Temporal bacterial and metabolic development of the preterm gut reveals specific signatures in health and disease. | 2016 | Microbiome | pmid:28034304 |
Jablonická V et al. | Identification of a secretory phospholipase A2 from Papaver somniferum L. that transforms membrane phospholipids. | 2016 | Phytochemistry | pmid:27473012 |
Arnold WR et al. | Asymmetric Binding and Metabolism of Polyunsaturated Fatty Acids (PUFAs) by CYP2J2 Epoxygenase. | 2016 | Biochemistry | pmid:27992998 |
Conte R et al. | Pressurized liquid extraction and chemical characterization of safflower oil: A comparison between methods. | 2016 | Food Chem | pmid:27451200 |
Montaño A et al. | Fatty Acid and Phenolic Compound Concentrations in Eight Different Monovarietal Virgin Olive Oils from Extremadura and the Relationship with Oxidative Stability. | 2016 | Int J Mol Sci | pmid:27886101 |
Zhao Z et al. | The Association of Fatty Acid Levels and Gleason Grade among Men Undergoing Radical Prostatectomy. | 2016 | PLoS ONE | pmid:27880795 |
Takabe W et al. | Esterification of 24S-OHC induces formation of atypical lipid droplet-like structures, leading to neuronal cell death. | 2016 | J. Lipid Res. | pmid:27647838 |
Zhang YH et al. | The Use of Gene Ontology Term and KEGG Pathway Enrichment for Analysis of Drug Half-Life. | 2016 | PLoS ONE | pmid:27780226 |
Matthaus B et al. | Some rape/canola seed oils: fatty acid composition and tocopherols. | 2016 | Z. Naturforsch., C, J. Biosci. | pmid:27023318 |
de Athayde Moncorvo Collado A et al. | Cholesterol induces surface localization of polyphenols in model membranes thus enhancing vesicle stability against lysozyme, but reduces protection of distant double bonds from reactive-oxygen species. | 2016 | Biochim. Biophys. Acta | pmid:27063609 |
Wood MH et al. | Comparative Adsorption of Saturated and Unsaturated Fatty Acids at the Iron Oxide/Oil Interface. | 2016 | Langmuir | pmid:26707597 |
Garsetti M et al. | Fat composition of vegetable oil spreads and margarines in the USA in 2013: a national marketplace analysis. | 2016 | Int J Food Sci Nutr | pmid:27046021 |
Bothun GD et al. | Cooperative effects of fatty acids and n-butanol on lipid membrane phase behavior. | 2016 | Colloids Surf B Biointerfaces | pmid:26700234 |
Wang JJ et al. | Two ω-3 FADs Are Associated with Peach Fruit Volatile Formation. | 2016 | Int J Mol Sci | pmid:27043529 |
Ramsden CE et al. | Dietary linoleic acid-induced alterations in pro- and anti-nociceptive lipid autacoids: Implications for idiopathic pain syndromes? | 2016 | Mol Pain | pmid:27030719 |
Domenichiello AF et al. | The effect of linoleic acid on the whole body synthesis rates of polyunsaturated fatty acids from α-linolenic acid and linoleic acid in free-living rats. | 2016 | J. Nutr. Biochem. | pmid:27012633 |
Yary T et al. | Serum n-6 polyunsaturated fatty acids, Δ5- and Δ6-desaturase activities, and risk of incident type 2 diabetes in men: the Kuopio Ischaemic Heart Disease Risk Factor Study. | 2016 | Am. J. Clin. Nutr. | pmid:27009754 |
Abdullah BM et al. | Polyesters Based on Linoleic Acid for Biolubricant Basestocks: Low-Temperature, Tribological and Rheological Properties. | 2016 | PLoS ONE | pmid:27008312 |