Linoleic acid
Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoleic acid?
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoleic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with Linoleic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoleic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Linoleic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoleic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lasa A et al. | The combination of resveratrol and CLA does not increase the delipidating effect of each molecule in 3T3-L1 adipocytes. | 2011 Sep-Oct | Nutr Hosp | pmid:22072344 |
| Mujtaba SF et al. | Production of ROS by photosensitized anthracene under sunlight and UV-R at ambient environmental intensities. | 2011 Sep-Oct | Photochem. Photobiol. | pmid:21668866 |
| Ramandi NF et al. | Central composite design for the optimization of supercritical carbon dioxide fluid extraction of fatty acids from Borago officinalis L. flower. | 2011 Nov-Dec | J. Food Sci. | pmid:22416687 |
| Olszewska MA | Variation in the phenolic content and in vitro antioxidant activity of Sorbus aucuparia leaf extracts during vegetation. | 2011 Nov-Dec | Acta Pol Pharm | pmid:22125960 |
| Olszewska MA | In vitro antioxidant activity and total phenolic content of the inflorescences, leaves and fruits of Sorbus torminalis (L.) Crantz. | 2011 Nov-Dec | Acta Pol Pharm | pmid:22125961 |
| Kezutyte T et al. | Study of tolnaftate release from fatty acids containing ointment and penetration into human skin ex vivo. | 2011 Nov-Dec | Acta Pol Pharm | pmid:22125963 |
| China R et al. | In vitro antioxidant activity of different cultivars of banana flower (Musa paradicicus L.) extracts available in India. | 2011 Nov-Dec | J. Food Sci. | pmid:22416691 |
| Qu WX et al. | Analysis of fatty acids in A. szechenyianum Gay. by microwave-assisted extraction and gas chromatography-mass spectrometry. | 2011 May-Jun | Phytochem Anal | pmid:20848395 |
| Lam YY et al. | Insulin-stimulated glucose uptake and pathways regulating energy metabolism in skeletal muscle cells: the effects of subcutaneous and visceral fat, and long-chain saturated, n-3 and n-6 polyunsaturated fatty acids. | 2011 Jul-Aug | Biochim. Biophys. Acta | pmid:21570480 |
| de Luis DA et al. | Double blind randomized clinical trial controlled by placebo with an alpha linoleic acid and prebiotic enriched cookie on risk cardiovascular factor in obese patients. | 2011 Jul-Aug | Nutr Hosp | pmid:22470031 |
| Aluf Y et al. | Alterations in striatal oxidative stress level produced by pharmacological manipulation of dopamine as shown by a novel synthetic marker molecule. | 2011 Jul-Aug | Neuropharmacology | pmid:21414328 |
| Kang J et al. | Identification of three genes encoding microsomal oleate desaturases (FAD2) from the oilseed crop Camelina sativa. | 2011 | Plant Physiol. Biochem. | pmid:21215650 |
| Park HG et al. | Production of conjugated linoleic acid (CLA) by Bifidobacterium breve LMC520 and its compatibility with CLA-producing rumen bacteria. | 2011 | J. Agric. Food Chem. | pmid:21192703 |
| Kruska N and Reiser G | Phytanic acid and pristanic acid, branched-chain fatty acids associated with Refsum disease and other inherited peroxisomal disorders, mediate intracellular Ca2+ signaling through activation of free fatty acid receptor GPR40. | 2011 | Neurobiol. Dis. | pmid:21570468 |
| Labayen I et al. | Associations of birth weight with serum long chain polyunsaturated fatty acids in adolescents; the HELENA study. | 2011 | Atherosclerosis | pmid:21550607 |
| Monfregola L et al. | Physical and water sorption properties of chemically modified pectin with an environmentally friendly process. | 2011 | Biomacromolecules | pmid:21553919 |
| Márquez-Castillo A and Vidal-Quintanar RL | Improvements in the shelf life of commercial corn dry masa flour (CMF) by reducing lipid oxidation. | 2011 | J. Food Sci. | pmid:21535741 |
| Yepuri G et al. | Dietary modulation of body composition and insulin sensitivity during catch-up growth in rats: effects of oils rich in n-6 or n-3 PUFA. | 2011 | Br. J. Nutr. | pmid:21281526 |
| de Lima-Salgado TM et al. | Molecular mechanisms by which saturated fatty acids modulate TNF-α expression in mouse macrophage lineage. | 2011 | Cell Biochem. Biophys. | pmid:20809180 |
| Andreu I et al. | Probing lipid peroxidation by using linoleic acid and benzophenone. | 2011 | Chemistry | pmid:21793062 |
| Shibata H et al. | Effect of supplementation of soy sauce oil and Ca salts of fatty acids on rumen fermentation, milk production and conjugated linoleic acid in milk of dairy cows. | 2011 | Anim. Sci. J. | pmid:21794014 |
| Prasad A and PospÃÅ¡il P | Linoleic acid-induced ultra-weak photon emission from Chlamydomonas reinhardtii as a tool for monitoring of lipid peroxidation in the cell membranes. | 2011 | PLoS ONE | pmid:21799835 |
| P Wrobel T et al. | Imaging of lipids in atherosclerotic lesion in aorta from ApoE/LDLR-/- mice by FT-IR spectroscopy and Hierarchical Cluster Analysis. | 2011 | Analyst | pmid:22007352 |
| Li YC et al. | Effects of conjugated linoleic acid on cleavage of amyloid precursor protein via PPARγ. | 2011 | Neurol. Sci. | pmid:21800078 |
| Shofian NM et al. | Effect of freeze-drying on the antioxidant compounds and antioxidant activity of selected tropical fruits. | 2011 | Int J Mol Sci | pmid:21845104 |
| Baâtour O et al. | Salt effects on Origanum majorana fatty acid and essential oil composition. | 2011 | J. Sci. Food Agric. | pmid:21800320 |
| Vedtofte MS et al. | Dietary α-linolenic acid, linoleic acid, and n-3 long-chain PUFA and risk of ischemic heart disease. | 2011 | Am. J. Clin. Nutr. | pmid:21865326 |
| Alimi H et al. | Evaluation of antioxidant and antiulcerogenic activities of Opuntia ficus indica f. inermis flowers extract in rats. | 2011 | Environ. Toxicol. Pharmacol. | pmid:22004960 |
| Ilić M et al. | Thrombin inhibitors with lipid peroxidation and lipoxygenase inhibitory activities. | 2011 | Bioorg. Med. Chem. Lett. | pmid:21757348 |
| Zened A et al. | Starch and oil in the donor cow diet and starch in substrate differently affect the in vitro ruminal biohydrogenation of linoleic and linolenic acids. | 2011 | J. Dairy Sci. | pmid:22032386 |
| Khadake R et al. | Functional and bioinformatic characterisation of sequence variants of Fad3 gene from flax. | 2011 | J. Sci. Food Agric. | pmid:21769878 |
| Gibson R and Makrides M | α-Linolenate reduces the dietary requirement for linoleate in the growing rat. | 2011 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22019216 |
| KonÄić MZ et al. | Antiradical, chelating and antioxidant activities of hydroxamic acids and hydroxyureas. | 2011 | Molecules | pmid:21788931 |
| Ramsden CE et al. | All PUFAs are not created equal: absence of CHD benefit specific to linoleic acid in randomized controlled trials and prospective observational cohorts. | 2011 | World Rev Nutr Diet | pmid:21865817 |
| Simon E et al. | Decreasing dietary linoleic acid promotes long chain omega-3 fatty acid incorporation into rat retina and modifies gene expression. | 2011 | Exp. Eye Res. | pmid:21821023 |
| Bowden JA et al. | Electrospray ionization tandem mass spectrometry of sodiated adducts of cholesteryl esters. | 2011 | Lipids | pmid:21904795 |
| Hanada H et al. | Induction of apoptosis and lipogenesis in human preadipocyte cell line by n-3 PUFAs. | 2011 | Cell Biol. Int. | pmid:20812919 |
| Lin YH et al. | Altered essential fatty acid metabolism and composition in rat liver, plasma, heart and brain after microalgal DHA addition to the diet. | 2011 | J. Nutr. Biochem. | pmid:21111595 |
| Zoia L et al. | Understanding the radical mechanism of lipoxygenases using 31P NMR spin trapping. | 2011 | Bioorg. Med. Chem. | pmid:21474321 |
| Martins SV et al. | Dietary conjugated linoleic acid isomers change the unsaturation degree of hepatic fatty acids in neutral lipids but not in polar lipids. | 2011 | Nutr Res | pmid:21481719 |
| Li M et al. | Isolation of a novel C18-Δ9 polyunsaturated fatty acid specific elongase gene from DHA-producing Isochrysis galbana H29 and its use for the reconstitution of the alternative Δ8 pathway in Saccharomyces cerevisiae. | 2011 | Biotechnol. Lett. | pmid:21538137 |
| Pi F et al. | Solid-state low temperature→middle temperature phase transition of linoleic acid studied by FTIR spectroscopy. | 2011 | J Phys Chem B | pmid:21520953 |
| Tsubura A et al. | Anticancer effects of garlic and garlic-derived compounds for breast cancer control. | 2011 | Anticancer Agents Med Chem | pmid:21269259 |
| Chohany LE et al. | Cationic substrates of soybean lipoxygenase-1. | 2011 | Bioorg. Chem. | pmid:21257189 |
| Das R et al. | Synthesis of linoleic acid capped copper nanoparticles and their fluorescence study. | 2011 | J Fluoresc | pmid:21221748 |
| Senadheera SD et al. | Effects of dietary α-linolenic acid (18:3n-3)/linoleic acid (18:2n-6) ratio on fatty acid metabolism in Murray cod (Maccullochella peelii peelii). | 2011 | J. Agric. Food Chem. | pmid:21222433 |
| Liu WM et al. | Effects of linoleic acid and eicosapentaenoic acid on cell proliferation and lipid-metabolism gene expression in primary duck hepatocytes. | 2011 | Mol. Cell. Biochem. | pmid:21274596 |
| Lin X et al. | Dietary conjugated linoleic acid alters long chain polyunsaturated fatty acid metabolism in brain and liver of neonatal pigs. | 2011 | J. Nutr. Biochem. | pmid:21216581 |
| Turk HF et al. | Linoleic acid and butyrate synergize to increase Bcl-2 levels in colonocytes. | 2011 | Int. J. Cancer | pmid:20232381 |
| Rosberg-Cody E et al. | Recombinant lactobacilli expressing linoleic acid isomerase can modulate the fatty acid composition of host adipose tissue in mice. | 2011 | Microbiology (Reading, Engl.) | pmid:21178166 |