Linoleic acid

Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.

Cross Reference

Introduction

To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoleic acid?

Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoleic acid

MeSH term MeSH ID Detail
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Fatty Liver D005234 48 associated lipids
Body Weight D001835 333 associated lipids
Precancerous Conditions D011230 48 associated lipids
Stomach Neoplasms D013274 24 associated lipids
Heart Failure D006333 36 associated lipids
Coronary Disease D003327 70 associated lipids
Alopecia D000505 14 associated lipids
Liver Diseases D008107 31 associated lipids
Per page 10 20 50 100 | Total 75

PubChem Associated disorders and diseases

What pathways are associated with Linoleic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with Linoleic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoleic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoleic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoleic acid

Download all related citations
Per page 10 20 50 100 | Total 4513
Authors Title Published Journal PubMed Link
Akamatsu H and Horio T The possible role of reactive oxygen species generated by neutrophils in mediating acne inflammation. 1998 Dermatology (Basel) pmid:9557235
Rosenfield RL et al. Mechanisms of androgen induction of sebocyte differentiation. 1998 Dermatology (Basel) pmid:9557223
Mennen L et al. Factor VIIa response to a fat-rich meal does not depend on fatty acid composition: a randomized controlled trial. 1998 Arterioscler. Thromb. Vasc. Biol. pmid:9555866
Kataoka K et al. Pathophysiologic studies of experimental chronic pancreatitis in rats induced by injection of zein-oleic acid-linoleic acid solution into the pancreatic duct. 1998 Pancreas pmid:9548669
Li-Stiles B et al. Identification and characterization of several forms of phospholipase A2 in mouse epidermal keratinocytes. 1998 J. Lipid Res. pmid:9548589
Liu SX et al. Oxidized cholesterol in oxidized low density lipoprotein may be responsible for the inhibition of LPS-induced nitric oxide production in macrophages. 1998 Atherosclerosis pmid:9544730
Matthys LA and Widmaier EP Fatty acids inhibit adrenocorticotropin-induced adrenal steroidogenesis. 1998 Horm. Metab. Res. pmid:9543689
Voskuyl RA et al. Anticonvulsant effect of polyunsaturated fatty acids in rats, using the cortical stimulation model. 1998 Eur. J. Pharmacol. pmid:9543232
Herrera JA et al. Prevention of preeclampsia by linoleic acid and calcium supplementation: a randomized controlled trial. 1998 Obstet Gynecol pmid:9540946
Liang JF and Akaike T Protective effect of linoleic acid on IFN gamma-induced cellular injury in primary culture hepatocytes. 1998 J. Biochem. pmid:9538194