Linoleic acid

Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.

Cross Reference

Introduction

To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoleic acid?

Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoleic acid

MeSH term MeSH ID Detail
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Fatty Liver D005234 48 associated lipids
Body Weight D001835 333 associated lipids
Precancerous Conditions D011230 48 associated lipids
Stomach Neoplasms D013274 24 associated lipids
Heart Failure D006333 36 associated lipids
Coronary Disease D003327 70 associated lipids
Alopecia D000505 14 associated lipids
Liver Diseases D008107 31 associated lipids
Per page 10 20 50 100 | Total 75

PubChem Associated disorders and diseases

What pathways are associated with Linoleic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with Linoleic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoleic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoleic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoleic acid

Download all related citations
Per page 10 20 50 100 | Total 4513
Authors Title Published Journal PubMed Link
Monastero R et al. Methylation patterns of Vegfb promoter are associated with gene and protein expression levels: the effects of dietary fatty acids. 2017 Eur J Nutr pmid:26707994
Buckley MT et al. Selection in Europeans on Fatty Acid Desaturases Associated with Dietary Changes. 2017 Mol. Biol. Evol. pmid:28333262
Liu Y and Roth JP A Revised Mechanism for Human Cyclooxygenase-2. 2016 J. Biol. Chem. pmid:26565028
Matthaus B et al. Some rape/canola seed oils: fatty acid composition and tocopherols. 2016 Z. Naturforsch., C, J. Biosci. pmid:27023318
Chiba T et al. The Precise Structures and Stereochemistry of Trihydroxy-linoleates Esterified in Human and Porcine Epidermis and Their Significance in Skin Barrier Function: IMPLICATION OF AN EPOXIDE HYDROLASE IN THE TRANSFORMATIONS OF LINOLEATE. 2016 J. Biol. Chem. pmid:27151221
Jumbe T et al. Whole Blood Levels of the n-6 Essential Fatty Acid Linoleic Acid Are Inversely Associated with Stunting in 2-to-6 Year Old Tanzanian Children: A Cross-Sectional Study. 2016 PLoS ONE pmid:27137223
McNamara RK and Welge JA Meta-analysis of erythrocyte polyunsaturated fatty acid biostatus in bipolar disorder. 2016 Bipolar Disord pmid:27087497
Ramsden CE et al. Re-evaluation of the traditional diet-heart hypothesis: analysis of recovered data from Minnesota Coronary Experiment (1968-73). 2016 BMJ pmid:27071971
Wood MH et al. Comparative Adsorption of Saturated and Unsaturated Fatty Acids at the Iron Oxide/Oil Interface. 2016 Langmuir pmid:26707597
Bothun GD et al. Cooperative effects of fatty acids and n-butanol on lipid membrane phase behavior. 2016 Colloids Surf B Biointerfaces pmid:26700234