Linoleic acid

Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.

Cross Reference

Introduction

To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoleic acid?

Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoleic acid

MeSH term MeSH ID Detail
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Fatty Liver D005234 48 associated lipids
Body Weight D001835 333 associated lipids
Precancerous Conditions D011230 48 associated lipids
Stomach Neoplasms D013274 24 associated lipids
Heart Failure D006333 36 associated lipids
Coronary Disease D003327 70 associated lipids
Alopecia D000505 14 associated lipids
Liver Diseases D008107 31 associated lipids
Per page 10 20 50 100 | Total 75

PubChem Associated disorders and diseases

What pathways are associated with Linoleic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with Linoleic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoleic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoleic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoleic acid

Download all related citations
Per page 10 20 50 100 | Total 4513
Authors Title Published Journal PubMed Link
Guarini P et al. Effects of dietary fish oil and soy phosphatidylcholine on neutrophil fatty acid composition, superoxide release, and adhesion. 1998 Inflammation pmid:9675609
Kelly ML et al. Effect of intake of pasture on concentrations of conjugated linoleic acid in milk of lactating cows. 1998 J. Dairy Sci. pmid:9684170
Demmelmair H et al. Metabolism of U13C-labeled linoleic acid in lactating women. 1998 J. Lipid Res. pmid:9684741
Kang LT and Vanderhoek JY Mono (S) hydroxy fatty acids: novel ligands for cytosolic actin. 1998 J. Lipid Res. pmid:9684751
Kato M et al. Reactivity of soybean lipoxygenase-1 to linoleic acid entrapped in phosphatidylcholine vesicles. 1998 J. Biochem. pmid:9685717
Fungwe TV et al. Fatty acids modulate lecithin:cholesterol acyltransferase secretion independently of effects on triglyceride secretion in primary rat hepatocytes. 1998 J. Nutr. pmid:9687543
Letawe C et al. Digital image analysis of the effect of topically applied linoleic acid on acne microcomedones. 1998 Clin. Exp. Dermatol. pmid:9692305
Hsu AF et al. Characterization of soybean lipoxygenase immobilized in cross-linked phyllosilicates. 1998 Biotechnol. Appl. Biochem. pmid:9693089
Goodrich-Tanrikulu M et al. Changes in fatty acid composition of Neurospora crassa accompany sexual development and ascospore germination. 1998 Microbiology (Reading, Engl.) pmid:9695905
Yamaguchi H et al. High transepidermal water loss induces fatty acid synthesis and cutaneous fatty acid-binding protein expression in rat skin. 1998 J. Dermatol. Sci. pmid:9697049