| MeSH term | MeSH ID | Detail |
|---|---|---|
| Aortic Diseases | D001018 | 11 associated lipids |
| Polycystic Kidney Diseases | D007690 | 12 associated lipids |
| Hypertrophy, Left Ventricular | D017379 | 12 associated lipids |
| Glucose Intolerance | D018149 | 13 associated lipids |
| Vitamin D Deficiency | D014808 | 13 associated lipids |
| Hypersensitivity, Immediate | D006969 | 14 associated lipids |
| Polycystic Ovary Syndrome | D011085 | 14 associated lipids |
| Alopecia | D000505 | 14 associated lipids |
| Malabsorption Syndromes | D008286 | 16 associated lipids |
| Olfaction Disorders | D000857 | 17 associated lipids |
Linoleic acid
Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoleic acid?
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoleic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with Linoleic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoleic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoleic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoleic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Torres CF and Hill CG | Lipase-catalyzed acidolysis of menhaden oil with conjugated linoleic acid: effect of water content. | 2002 | Biotechnol. Bioeng. | pmid:12115120 |
| Gassull MA et al. | Fat composition may be a clue to explain the primary therapeutic effect of enteral nutrition in Crohn's disease: results of a double blind randomised multicentre European trial. | 2002 | Gut | pmid:12117873 |
| Blée E | Impact of phyto-oxylipins in plant defense. | 2002 | Trends Plant Sci. | pmid:12119169 |
| Tracy RE and Walia P | A method to fix lipids for staining fat embolism in paraffin sections. | 2002 | Histopathology | pmid:12121240 |
| Kim EJ et al. | Trans-10,cis-12-conjugated linoleic acid inhibits Caco-2 colon cancer cell growth. | 2002 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:12121883 |
| Ha J et al. | Effect of linoleic acid metabolites on Na(+)/K(+) pump current in N20.1 oligodendrocytes: role of membrane fluidity. | 2002 | Toxicol. Appl. Pharmacol. | pmid:12127265 |
| Papetti A et al. | Anti- and pro-oxidant water soluble activity of Cichorium genus vegetables and effect of thermal treatment. | 2002 | J. Agric. Food Chem. | pmid:12137499 |
| Boydak E et al. | Seed composition of soybeans grown in the Harran region of Turkey as affected by row spacing and irrigation. | 2002 | J. Agric. Food Chem. | pmid:12137503 |
| Askari B et al. | Oleate and linoleate enhance the growth-promoting effects of insulin-like growth factor-I through a phospholipase D-dependent pathway in arterial smooth muscle cells. | 2002 | J. Biol. Chem. | pmid:12138107 |
| Hansen RA et al. | Effects of dietary flaxseed oil supplementation on equine plasma fatty acid concentrations and whole blood platelet aggregation. | 2002 Jul-Aug | J. Vet. Intern. Med. | pmid:12141309 |
| Akakabe Y et al. | Enantioselective formation of (R)-9-HPODE and (R)-9-HPOTrE in marine green alga Ulva conglobata. | 2002 | Bioorg. Med. Chem. | pmid:12150862 |
| Armstrong D et al. | Preparation of microspheres and incorporation of lipid hydroperoxide for sustained release studies. | 2002 | Methods Mol. Biol. | pmid:12152211 |
| Ghebremeskel K et al. | Liver triacylglycerols and free fatty acids in streptozotocin-induced diabetic rats have atypical n-6 and n-3 pattern. | 2002 | Comp. Biochem. Physiol. C Toxicol. Pharmacol. | pmid:12161168 |
| Thibodeau PA et al. | In vitro pro- and antioxidant properties of estrogens. | 2002 | J. Steroid Biochem. Mol. Biol. | pmid:12163134 |
| Yang L et al. | Differential incorporation of conjugated linoleic acid isomers into egg yolk lipids. | 2002 | J. Agric. Food Chem. | pmid:12166986 |
| Lee MH et al. | Therapeutic effect of topical application of linoleic acid and lincomycin in combination with betamethasone valerate in melasma patients. | 2002 | J. Korean Med. Sci. | pmid:12172049 |
| Cruz JC et al. | Synthesis and biochemical properties of a new photoactivatable cholesterol analog 7,7-azocholestanol and its linoleate ester in Chinese hamster ovary cell lines. | 2002 | J. Lipid Res. | pmid:12177179 |
| Turner ND et al. | Oncogenic ras alters sensitivity of mouse colonocytes to butyrate and fatty acid mediated growth arrest and apoptosis. | 2002 | Cancer Lett. | pmid:12183072 |
| Ling PR et al. | Disturbances in essential fatty acid metabolism in patients receiving long-term home parenteral nutrition. | 2002 | Dig. Dis. Sci. | pmid:12184517 |
| Pilitsis JG et al. | Free fatty acids in human cerebrospinal fluid following subarachnoid hemorrhage and their potential role in vasospasm: a preliminary observation. | 2002 | J. Neurosurg. | pmid:12186453 |
| Lima ES et al. | Characterization of linoleic acid nitration in human blood plasma by mass spectrometry. | 2002 | Biochemistry | pmid:12186558 |
| Thiesen A et al. | Dietary lipids alter the effect of steroids on the uptake of lipids following intestinal resection in rats. | 2002 | Dig. Dis. Sci. | pmid:12187929 |
| Kuo TM et al. | Conversion of fatty acids by Bacillus sphaericus-like organisms. | 2002 | Curr. Microbiol. | pmid:12192524 |
| Risérus U et al. | Treatment with dietary trans10cis12 conjugated linoleic acid causes isomer-specific insulin resistance in obese men with the metabolic syndrome. | 2002 | Diabetes Care | pmid:12196420 |
| Hourton-Cabassa C et al. | Alteration of plant mitochondrial proton conductance by free fatty acids. Uncoupling protein involvement. | 2002 | J. Biol. Chem. | pmid:12196511 |
| Turpeinen AM et al. | Bioconversion of vaccenic acid to conjugated linoleic acid in humans. | 2002 | Am. J. Clin. Nutr. | pmid:12197992 |
| Yang H et al. | Sex-specific induction of mutations by PhIP in the kidney of male and female rats and its modulation by conjugated linoleic acid. | 2002 | Environ. Mol. Mutagen. | pmid:12203404 |
| Tithof PK et al. | Polycyclic aromatic hydrocarbons present in cigarette smoke cause endothelial cell apoptosis by a phospholipase A2-dependent mechanism. | 2002 | FASEB J. | pmid:12205049 |
| Ko TF et al. | Squalene content and antioxidant activity of Terminalia catappa leaves and seeds. | 2002 | J. Agric. Food Chem. | pmid:12207472 |
| Nuchi CD et al. | Ability of lipid hydroperoxides to partition into surfactant micelles and alter lipid oxidation rates in emulsions. | 2002 | J. Agric. Food Chem. | pmid:12207489 |
| Noone EJ et al. | The effect of dietary supplementation using isomeric blends of conjugated linoleic acid on lipid metabolism in healthy human subjects. | 2002 | Br. J. Nutr. | pmid:12207834 |
| Bottger JD et al. | Effects of supplementation with high linoleic or oleic cracked safflower seeds on postpartum reproduction and calf performance of primiparous beef heifers. | 2002 | J. Anim. Sci. | pmid:12211368 |
| Smith SB et al. | Conjugated linoleic acid depresses the delta9 desaturase index and stearoyl coenzyme A desaturase enzyme activity in porcine subcutaneous adipose tissue. | 2002 | J. Anim. Sci. | pmid:12211379 |
| Göbel C et al. | Oxylipin profiling in pathogen-infected potato leaves. | 2002 | Biochim. Biophys. Acta | pmid:12213493 |
| Giesy JG et al. | Effect of dose of calcium salts of conjugated linoleic acid (CLA) on percentage and fatty acid content of milk fat in midlactation holstein cows. | 2002 | J. Dairy Sci. | pmid:12214995 |
| Freedman JE | Nitrated lipids: defining their bioactivity. | 2002 | Circ. Res. | pmid:12215483 |
| Coles B et al. | Nitrolinoleate inhibits superoxide generation, degranulation, and integrin expression by human neutrophils: novel antiinflammatory properties of nitric oxide-derived reactive species in vascular cells. | 2002 | Circ. Res. | pmid:12215485 |
| Gulcin I et al. | On the in vitro antioxidative properties of melatonin. | 2002 | J. Pineal Res. | pmid:12220332 |
| Bouthegourd JC et al. | A CLA mixture prevents body triglyceride accumulation without affecting energy expenditure in Syrian hamsters. | 2002 | J. Nutr. | pmid:12221229 |
| Clément L et al. | Dietary trans-10,cis-12 conjugated linoleic acid induces hyperinsulinemia and fatty liver in the mouse. | 2002 | J. Lipid Res. | pmid:12235171 |
| Blank C et al. | Optimizing DHA levels in piglets by lowering the linoleic acid to alpha-linolenic acid ratio. | 2002 | J. Lipid Res. | pmid:12235186 |
| Newman JW et al. | The simultaneous quantification of cytochrome P450 dependent linoleate and arachidonate metabolites in urine by HPLC-MS/MS. | 2002 | J. Lipid Res. | pmid:12235189 |
| Harrell MD and Stimers JR | Differential effects of linoleic Acid metabolites on cardiac sodium current. | 2002 | J. Pharmacol. Exp. Ther. | pmid:12235270 |
| Du M et al. | Quality characteristics of irradiated ready-to-eat breast rolls from turkeys fed conjugated linoleic acid. | 2002 | Poult. Sci. | pmid:12269620 |
| Yang L et al. | Production of conjugated linoleic acids through KOH-catalyzed dehydration of ricinoleic acid. | 2002 | Chem. Phys. Lipids | pmid:12270670 |
| Fang JG et al. | Antioxidant effects of resveratrol and its analogues against the free-radical-induced peroxidation of linoleic acid in micelles. | 2002 | Chemistry | pmid:12298009 |
| Goodfriend TL et al. | An oxidized derivative of linoleic acid affects aldosterone secretion by adrenal cells in vitro. | 2002 Aug-Sep | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12324236 |
| Baylin A et al. | Adipose tissue biomarkers of fatty acid intake. | 2002 | Am. J. Clin. Nutr. | pmid:12324287 |
| Voorrips LE et al. | Intake of conjugated linoleic acid, fat, and other fatty acids in relation to postmenopausal breast cancer: the Netherlands Cohort Study on Diet and Cancer. | 2002 | Am. J. Clin. Nutr. | pmid:12324303 |
| Itoh A et al. | Identification of a jasmonate-regulated allene oxide synthase that metabolizes 9-hydroperoxides of linoleic and linolenic acids. | 2002 | J. Biol. Chem. | pmid:12351632 |