| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hyperpigmentation | D017495 | 11 associated lipids |
| Hypertrophy, Left Ventricular | D017379 | 12 associated lipids |
| Polycystic Kidney Diseases | D007690 | 12 associated lipids |
| Vitamin D Deficiency | D014808 | 13 associated lipids |
| Glucose Intolerance | D018149 | 13 associated lipids |
| Hypersensitivity, Immediate | D006969 | 14 associated lipids |
| Polycystic Ovary Syndrome | D011085 | 14 associated lipids |
| Alopecia | D000505 | 14 associated lipids |
| Malabsorption Syndromes | D008286 | 16 associated lipids |
| Olfaction Disorders | D000857 | 17 associated lipids |
Linoleic acid
Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoleic acid?
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoleic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with Linoleic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoleic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoleic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoleic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ahn DU et al. | Effect of dietary conjugated linoleic acid on the quality characteristics of chicken eggs during refrigerated storage. | 1999 | Poult. Sci. | pmid:10438141 |
| Rudel LL | Atherosclerosis and conjugated linoleic acid. | 1999 | Br. J. Nutr. | pmid:10434843 |
| Yamasaki M et al. | Dietary effect of conjugated linoleic acid on lipid levels in white adipose tissue of Sprague-Dawley rats. | 1999 | Biosci. Biotechnol. Biochem. | pmid:10427699 |
| Calvo AM et al. | Sporogenic effect of polyunsaturated fatty acids on development of Aspergillus spp. | 1999 | Appl. Environ. Microbiol. | pmid:10427064 |
| Demmelmair H et al. | Comparison of bolus versus fractionated oral applications of [13C]-linoleic acid in humans. | 1999 | Eur. J. Clin. Invest. | pmid:10411666 |
| Sammon AM | Maize meal, non-esterified linoleic acid, and endemic cancer of the esophagus--preliminary findings. | 1999 | Prostaglandins Other Lipid Mediat. | pmid:10410386 |
| Kim S et al. | C/EBPbeta (NF-M) is essential for activation of the p20K lipocalin gene in growth-arrested chicken embryo fibroblasts. | 1999 | Mol. Cell. Biol. | pmid:10409760 |
| Ding XZ et al. | Lipoxygenase inhibitors abolish proliferation of human pancreatic cancer cells. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10405349 |
| Murakami K et al. | Evidence for direct binding of fatty acids and eicosanoids to human peroxisome proliferators-activated receptor alpha. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10403814 |
| Dontsov AE et al. | Retinal pigment epithelium pigment granules stimulate the photo-oxidation of unsaturated fatty acids. | 1999 | Free Radic. Biol. Med. | pmid:10401607 |
| O'Donnell VB et al. | 15-Lipoxygenase catalytically consumes nitric oxide and impairs activation of guanylate cyclase. | 1999 | J. Biol. Chem. | pmid:10400618 |
| Andersen LF et al. | Evaluation of a food frequency questionnaire with weighed records, fatty acids, and alpha-tocopherol in adipose tissue and serum. | 1999 | Am. J. Epidemiol. | pmid:10400557 |
| Ingkaninan K et al. | Interference of linoleic acid fraction in some receptor binding assays. | 1999 | J. Nat. Prod. | pmid:10395519 |
| Hidaka T et al. | Screening of microbial products modifying the action of leptin (obese gene product) by a biosensor. | 1999 | J. Antibiot. | pmid:10395281 |
| Ando H et al. | Possible involvement of proteolytic degradation of tyrosinase in the regulatory effect of fatty acids on melanogenesis. | 1999 | J. Lipid Res. | pmid:10393216 |
| Su HM et al. | Linoleic acid kinetics and conversion to arachidonic acid in the pregnant and fetal baboon. | 1999 | J. Lipid Res. | pmid:10393215 |
| Jeppesen PB et al. | Differences in essential fatty acid requirements by enteral and parenteral routes of administration in patients with fat malabsorption. | 1999 | Am. J. Clin. Nutr. | pmid:10393142 |
| Jiang J et al. | Relation between the intake of milk fat and the occurrence of conjugated linoleic acid in human adipose tissue. | 1999 | Am. J. Clin. Nutr. | pmid:10393134 |
| Greenberg D et al. | Differential satiating effects of fats in the small intestine of obesity-resistant and obesity-prone rats. | 1999 | Physiol. Behav. | pmid:10386906 |
| Parodi PW | Conjugated linoleic acid and other anticarcinogenic agents of bovine milk fat. | 1999 | J. Dairy Sci. | pmid:10386321 |
| Akeo K et al. | Effects of fluorescent light on growth of bovine retinal pigment epithelial cells in vitro incubated with linoleic acid or linoleic acid hydroperoxide. | 1999 | Pigment Cell Res. | pmid:10385917 |
| Forster C et al. | Molecular analysis of a null mutant for pea (Pisum sativum L.) seed lipoxygenase-2. | 1999 | Plant Mol. Biol. | pmid:10380807 |
| Gänzle MG et al. | Resistance of Escherichia coli and Salmonella against nisin and curvacin A. | 1999 | Int. J. Food Microbiol. | pmid:10375133 |
| Kavanaugh CJ et al. | Effect of dietary conjugated linoleic acid on phorbol ester-induced PGE2 production and hyperplasia in mouse epidermis. | 1999 | Nutr Cancer | pmid:10368807 |
| Stimers JR et al. | Effects of linoleic acid metabolites on electrical activity in adult rat ventricular myocytes. | 1999 | Biochim. Biophys. Acta | pmid:10366778 |
| Dodge ML et al. | Glutathione peroxidase activity modulates fatty acid profiles of plasma and breast milk in Chinese women. | 1999 | J Trace Elem Med Biol | pmid:10365375 |
| Alava MA et al. | Fatty acid desaturation: effect of alphafetoprotein on alpha-linolenic acid conversion by fetal rat hepatocytes. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10359023 |
| Hilakivi-Clarke L et al. | The influence of maternal diet on breast cancer risk among female offspring. | 1999 | Nutrition | pmid:10355854 |
| Fukushima M et al. | Effects of a mixture of organisms, Lactobacillus acidophilus or Streptococcus faecalis on delta6-desaturase activity in the livers of rats fed a fat- and cholesterol-enriched diet. | 1999 | Nutrition | pmid:10355850 |
| Meuillet EJ et al. | Incorporation of exogenous lipids modulates insulin signaling in the hepatoma cell line, HepG2. | 1999 | Biochim. Biophys. Acta | pmid:10354513 |
| Yen GC and Hsieh CL | Antioxidant effects of dopamine and related compounds. | 1997 | Biosci. Biotechnol. Biochem. | pmid:10336274 |
| Nuñez A et al. | Cofactor recycling in a coupled enzyme oxidation-reduction reaction: conversion of omega-oxo-fatty acids into omega-hydroxy and dicarboxylic acids. | 1999 | Biotechnol. Appl. Biochem. | pmid:10334949 |
| Kapich A et al. | Coupling of manganese peroxidase-mediated lipid peroxidation with destruction of nonphenolic lignin model compounds and 14C-labeled lignins. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10334942 |
| Wei T et al. | Antioxidant properties of EPC-K1: a study on mechanisms. | 1999 | Biophys. Chem. | pmid:10326248 |
| Haggarty P et al. | Effect of maternal polyunsaturated fatty acid concentration on transport by the human placenta. | 1999 | Biol. Neonate | pmid:10325438 |
| Geetha T and Varalakshmi P | Anticomplement activity of triterpenes from Crataeva nurvala stem bark in adjuvant arthritis in rats. | 1999 | Gen. Pharmacol. | pmid:10323491 |
| Burke PA et al. | Conditionally essential fatty acid deficiencies in end-stage liver disease. | 1999 | Nutrition | pmid:10319364 |
| Iuliano L et al. | Protection of low density lipoprotein oxidation by the antioxidant agent IRFI005, a new synthetic hydrophilic vitamin E analogue. | 1999 | Free Radic. Biol. Med. | pmid:10232829 |
| Szitanyi P et al. | Metabolism of 13C-labeled linoleic acid in newborn infants during the first week of life. | 1999 | Pediatr. Res. | pmid:10231862 |
| Banni S et al. | An increase in vitamin A status by the feeding of conjugated linoleic acid. | 1999 | Nutr Cancer | pmid:10227044 |
| Cortez-Pinto H et al. | Lipids up-regulate uncoupling protein 2 expression in rat hepatocytes. | 1999 | Gastroenterology | pmid:10220511 |
| Minich DM et al. | Bile diversion in rats leads to a decreased plasma concentration of linoleic acid which is not due to decreased net intestinal absorption of dietary linoleic acid. | 1999 | Biochim. Biophys. Acta | pmid:10216285 |
| Spaide RF et al. | Characterization of peroxidized lipids in Bruch's membrane. | 1999 | Retina (Philadelphia, Pa.) | pmid:10213241 |
| Bergamini S et al. | Prooxidant activity of ferrioxamine in isolated rat hepatocytes and linoleic acid micelles. | 1999 | Chem. Res. Toxicol. | pmid:10207126 |
| DeLany JP et al. | Conjugated linoleic acid rapidly reduces body fat content in mice without affecting energy intake. | 1999 | Am. J. Physiol. | pmid:10198400 |
| Jayawickreme SP et al. | Regulation of 15-lipoxygenase expression and mucus secretion by IL-4 in human bronchial epithelial cells. | 1999 | Am. J. Physiol. | pmid:10198357 |
| Augé N et al. | Uptake of 13-hydroperoxylinoleic acid by cultured cells. | 1999 | Arterioscler. Thromb. Vasc. Biol. | pmid:10195919 |
| Stewart JM et al. | Comparisons of the effects of temperature on the liver fatty acid binding proteins from hibernator and nonhibernator mammals. | 1998 | Biochem. Cell Biol. | pmid:10099779 |
| Galli A et al. | High-level expression of rat class I alcohol dehydrogenase is sufficient for ethanol-induced fat accumulation in transduced HeLa cells. | 1999 | Hepatology | pmid:10094961 |
| Brodie AE et al. | Conjugated linoleic acid inhibits differentiation of pre- and post- confluent 3T3-L1 preadipocytes but inhibits cell proliferation only in preconfluent cells. | 1999 | J. Nutr. | pmid:10082762 |