Linoleic acid

Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.

Cross Reference

Introduction

To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoleic acid?

Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoleic acid

MeSH term MeSH ID Detail
Coronary Disease D003327 70 associated lipids
Colitis D003092 69 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Pain D010146 64 associated lipids
Weight Loss D015431 56 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Thrombosis D013927 49 associated lipids
Fatty Liver D005234 48 associated lipids
Precancerous Conditions D011230 48 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Per page 10 20 50 100 | Total 75

PubChem Associated disorders and diseases

What pathways are associated with Linoleic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with Linoleic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoleic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoleic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoleic acid

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Per page 10 20 50 100 | Total 4513
Authors Title Published Journal PubMed Link
Ozen T Investigation of antioxidant properties of Nasturtium officinale (watercress) leaf extracts. 2009 Mar-Apr Acta Pol Pharm pmid:19719054
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Inoue N et al. Linoleic acid-menthyl ester reduces the secretion of apolipoprotein B100 in HepG2 cells. 2009 J Oleo Sci pmid:19282639
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Adiguzel A et al. Antimicrobial and antioxidant activity of the essential oil and methanol extract of Nepeta cataria. 2009 Pol. J. Microbiol. pmid:19469289
Dauchy RT et al. Antineoplastic effects of melatonin on a rare malignancy of mesenchymal origin: melatonin receptor-mediated inhibition of signal transduction, linoleic acid metabolism and growth in tissue-isolated human leiomyosarcoma xenografts. 2009 J. Pineal Res. pmid:19486272
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Zhang M et al. Cytotoxic aggregates of alpha-lactalbumin induced by unsaturated fatty acid induce apoptosis in tumor cells. 2009 Chem. Biol. Interact. pmid:19497410
Villa PM et al. Free fatty acid profiles in preeclampsia. 2009 Prostaglandins Leukot. Essent. Fatty Acids pmid:19497719
Marosvölgyi T et al. Trans isomeric and LCPUFA are inversely correlated in erythrocyte membrane lipids at mid-gestation. 2009 Adv. Exp. Med. Biol. pmid:19536675
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Fukasawa R et al. Anti-oxidative effects of rooibos tea extract on autoxidation and thermal oxidation of lipids. 2009 J Oleo Sci pmid:19430189
Evans LM et al. Dietary stearate reduces human breast cancer metastasis burden in athymic nude mice. 2009 Clin. Exp. Metastasis pmid:19267249
Mimoun M et al. Increased tissue arachidonic acid and reduced linoleic acid in a mouse model of cystic fibrosis are reversed by supplemental glycerophospholipids enriched in docosahexaenoic acid. 2009 J. Nutr. pmid:19828687
Artwohl M et al. Fatty acids induce apoptosis in human smooth muscle cells depending on chain length, saturation, and duration of exposure. 2009 Atherosclerosis pmid:18597758
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Shimomura H et al. Steroids mediate resistance to the bactericidal effect of phosphatidylcholines against Helicobacter pylori. 2009 FEMS Microbiol. Lett. pmid:19843309
Chechetkin IR et al. Specificity of oxidation of linoleic acid homologs by plant lipoxygenases. 2009 Biochemistry Mosc. pmid:19817685
Grossmann ME et al. Eleostearic Acid inhibits breast cancer proliferation by means of an oxidation-dependent mechanism. 2009 Cancer Prev Res (Phila) pmid:19789297