Linoleic acid

Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.

Cross Reference

Introduction

To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoleic acid?

Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoleic acid

MeSH term MeSH ID Detail
Tuberculosis D014376 20 associated lipids
Thrombosis D013927 49 associated lipids
Stomach Neoplasms D013274 24 associated lipids
Staphylococcal Skin Infections D013207 9 associated lipids
Spirochaetales Infections D013145 2 associated lipids
Seizures D012640 87 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Pregnancy Complications, Neoplastic D011252 4 associated lipids
Precancerous Conditions D011230 48 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoleic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with Linoleic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoleic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoleic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoleic acid

Download all related citations
Per page 10 20 50 100 | Total 4513
Authors Title Published Journal PubMed Link
Griffin ME et al. Non-insulin-dependent diabetes mellitus: dietary monounsaturated fatty acids and low-density lipoprotein composition and function. 1996 QJM pmid:8731565
Combet E et al. Development of an in vitro system combining aqueous and lipid phases as a tool to understand gastric nitrosation. 2010 Rapid Commun. Mass Spectrom. pmid:20112267
Gakwaya R et al. Examining the collision-induced decomposition spectra of ammoniated triglycerides. III. The linoleate and arachidonate series. 2007 Rapid Commun. Mass Spectrom. pmid:17893948
Ladeira MM et al. Lipids in the diet and the fatty acid profile in beef: a review and recent patents on the topic. 2012 Recent Pat Food Nutr Agric pmid:22702746
Asselin C et al. Circulating levels of linoleic acid and HDL-cholesterol are major determinants of 4-hydroxynonenal protein adducts in patients with heart failure. 2014 Redox Biol pmid:24494189
Zhu X and Sayre LM Mass spectrometric evidence for long-lived protein adducts of 4-oxo-2-nonenal. 2007 Redox Rep. pmid:17263908
Masella R et al. Antioxidant activity of 3,4-DHPEA-EA and protocatechuic acid: a comparative assessment with other olive oil biophenols. 1999 Redox Rep. pmid:10496414
Kritharides L Ascorbic acid and copper in linoleate oxidation--Dunkley revisited. 1999 Redox Rep. pmid:10772064
Rittmann BE and Schloendorn J Engineering away lysosomal junk: medical bioremediation. 2007 Rejuvenation Res pmid:17708688
Walsh SW Plasma from preeclamptic women stimulates transendothelial migration of neutrophils. 2009 Reprod Sci pmid:19087976