| MeSH term | MeSH ID | Detail |
|---|---|---|
| Kidney Diseases | D007674 | 29 associated lipids |
| Endometrial Neoplasms | D016889 | 30 associated lipids |
| Liver Diseases | D008107 | 31 associated lipids |
| Heart Failure | D006333 | 36 associated lipids |
| Metabolic Syndrome | D024821 | 44 associated lipids |
| Metabolism, Inborn Errors | D008661 | 46 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Weight Loss | D015431 | 56 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Seizures | D012640 | 87 associated lipids |
Linoleic acid
Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoleic acid?
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoleic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with Linoleic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoleic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoleic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoleic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Song E et al. | Deamidated lipocalin-2 induces endothelial dysfunction and hypertension in dietary obese mice. | 2014 | J Am Heart Assoc | pmid:24721803 |
| Reed S et al. | Dietary zinc deficiency affects blood linoleic acid: dihomo-γ-linolenic acid (LA:DGLA) ratio; a sensitive physiological marker of zinc status in vivo (Gallus gallus). | 2014 | Nutrients | pmid:24658588 |
| Petrogianni M et al. | Additional benefit in CVD risk indices derived from the consumption of fortified milk when combined with a lifestyle intervention. | 2014 | Public Health Nutr | pmid:23249766 |
| Huang X et al. | Serum and adipose tissue fatty acid composition as biomarkers of habitual dietary fat intake in elderly men with chronic kidney disease. | 2014 | Nephrol. Dial. Transplant. | pmid:23229929 |
| Bernhard W et al. | Plasma phospholipids indicate impaired fatty acid homeostasis in preterm infants. | 2014 | Eur J Nutr | pmid:24464176 |
| Armstrong EH et al. | Structural basis for ligand regulation of the fatty acid-binding protein 5, peroxisome proliferator-activated receptor β/δ (FABP5-PPARβ/δ) signaling pathway. | 2014 | J. Biol. Chem. | pmid:24692551 |
| Hodson L et al. | Plasma and erythrocyte fatty acids reflect intakes of saturated and n-6 PUFA within a similar time frame. | 2014 | J. Nutr. | pmid:24225449 |
| Bagai S et al. | Lipid-modified polyethylenimine-mediated DNA attraction evaluated by molecular dynamics simulations. | 2014 | J Phys Chem B | pmid:24918771 |
| Qin G et al. | Evolution of the aroma volatiles of pear fruits supplemented with fatty acid metabolic precursors. | 2014 | Molecules | pmid:25474290 |
| Ebrahimi M et al. | Effects of oils rich in linoleic and α-linolenic acids on fatty acid profile and gene expression in goat meat. | 2014 | Nutrients | pmid:25255382 |
| Xu QY et al. | Metabolomic analysis of simvastatin and fenofibrate intervention in high-lipid diet-induced hyperlipidemia rats. | 2014 | Acta Pharmacol. Sin. | pmid:25220639 |
| Victoria FN et al. | Antioxidant and antidepressant-like activities of semi-synthetic α-phenylseleno citronellal. | 2014 | Eur. J. Pharmacol. | pmid:25218989 |
| Farvid MS et al. | Dietary linoleic acid and risk of coronary heart disease: a systematic review and meta-analysis of prospective cohort studies. | 2014 | Circulation | pmid:25161045 |
| Harris WS and Shearer GC | Omega-6 fatty acids and cardiovascular disease: friend, not foe? | 2014 | Circulation | pmid:25161044 |
| Saito HE et al. | Incorporation of exogenous fatty acids protects Enterococcus faecalis from membrane-damaging agents. | 2014 | Appl. Environ. Microbiol. | pmid:25128342 |
| Wu JH et al. | Circulating omega-6 polyunsaturated fatty acids and total and cause-specific mortality: the Cardiovascular Health Study. | 2014 | Circulation | pmid:25124495 |
| Phan CW et al. | Intrastrain comparison of the chemical composition and antioxidant activity of an edible mushroom, Pleurotus giganteus, and its potent neuritogenic properties. | 2014 | ScientificWorldJournal | pmid:25121118 |
| Buehlmann C et al. | Desert ants locate food by combining high sensitivity to food odors with extensive crosswind runs. | 2014 | Curr. Biol. | pmid:24726153 |
| BuÄek A et al. | Δ12-Fatty acid desaturase from Candida parapsilosis is a multifunctional desaturase producing a range of polyunsaturated and hydroxylated fatty acids. | 2014 | PLoS ONE | pmid:24681902 |
| Rodriguez MA et al. | Concordance analysis between estimation methods of milk fatty acid content. | 2014 | Food Chem | pmid:24629954 |
| Spartano NL et al. | Linoleic acid suppresses cholesterol efflux and ATP-binding cassette transporters in murine bone marrow-derived macrophages. | 2014 | Lipids | pmid:24595513 |
| Scalerandi MV et al. | Effect of conjugated linoleic acid mixtures and different edible oils in body composition and lipid regulation in mice. | 2014 | Nutr Hosp | pmid:24559004 |
| Nadtochiy SM et al. | Mitochondrially targeted nitro-linoleate: a new tool for the study of cardioprotection. | 2014 | Br. J. Pharmacol. | pmid:24102583 |
| Choi JI et al. | Development of microalga Scenedesmus dimorphus mutant with higher lipid content by radiation breeding. | 2014 | Bioprocess Biosyst Eng | pmid:24871276 |
| Guo HH et al. | XsFAD2 gene encodes the enzyme responsible for the high linoleic acid content in oil accumulated in Xanthoceras sorbifolia seeds. | 2014 | J. Sci. Food Agric. | pmid:23775588 |
| Huang X et al. | Serum fatty acid patterns, insulin sensitivity and the metabolic syndrome in individuals with chronic kidney disease. | 2014 | J. Intern. Med. | pmid:24011327 |
| Radice M et al. | Chemical characterization and antioxidant activity of Amazonian (Ecuador) Caryodendron orinocense Karst. and Bactris gasipaes Kunth seed oils. | 2014 | J Oleo Sci | pmid:25391685 |
| Kim JY et al. | Role of moisture on the lipid oxidation determined by D(2)O in a linoleic acid model system. | 2014 | Food Chem | pmid:24176324 |
| Sponton OE et al. | Effect of limited enzymatic hydrolysis on linoleic acid binding properties of β-lactoglobulin. | 2014 | Food Chem | pmid:24176383 |
| Dal Bosco A et al. | Effect of dietary alfalfa on the fatty acid composition and indexes of lipid metabolism of rabbit meat. | 2014 | Meat Sci. | pmid:24036258 |
| Alvheim AR et al. | Dietary linoleic acid elevates the endocannabinoids 2-AG and anandamide and promotes weight gain in mice fed a low fat diet. | 2014 | Lipids | pmid:24081493 |
| López-Cervantes J et al. | Effect of solvents and methods of stirring in extraction of lycopene, oleoresin and fatty acids from over-ripe tomato. | 2014 | Int J Food Sci Nutr | pmid:24111501 |
| Bakır T et al. | Antioxidant/prooxidant effects of α-tocopherol, quercetin and isorhamnetin on linoleic acid peroxidation induced by Cu(II) and H2O2. | 2014 | Int J Food Sci Nutr | pmid:24152374 |
| Wennman A et al. | Kinetic investigation of the rate-limiting step of manganese- and iron-lipoxygenases. | 2014 | Arch. Biochem. Biophys. | pmid:24857825 |
| Huang FC et al. | Expression and characterization of CYP52 genes involved in the biosynthesis of sophorolipid and alkane metabolism from Starmerella bombicola. | 2014 | Appl. Environ. Microbiol. | pmid:24242247 |
| López A et al. | Compressive mechanical properties and cytocompatibility of bone-compliant, linoleic acid-modified bone cement in a bovine model. | 2014 | J Mech Behav Biomed Mater | pmid:24508711 |
| Larsson N et al. | Lipid mediator profiles differ between lung compartments in asthmatic and healthy humans. | 2014 | Eur. Respir. J. | pmid:24036245 |
| Yang Q et al. | Anti-thrombotic effects of α-linolenic acid isolated from Zanthoxylum bungeanum Maxim seeds. | 2014 | BMC Complement Altern Med | pmid:25252789 |
| Yang Y et al. | Lipidomic analyses of female mice lacking hepatic lipase and endothelial lipase indicate selective modulation of plasma lipid species. | 2014 | Lipids | pmid:24777581 |
| Wu MH et al. | A novel sodium N-fatty acyl amino acid surfactant using silkworm pupae as stock material. | 2014 | Sci Rep | pmid:24651079 |
| Chevrot M et al. | Obesity interferes with the orosensory detection of long-chain fatty acids in humans. | 2014 | Am. J. Clin. Nutr. | pmid:24522446 |
| Barua P et al. | Seed oils from non-conventional sources in north-east India: potential feedstock for production of biodiesel. | 2014 | Nat. Prod. Res. | pmid:24483850 |
| Matthaus B and Özcan MM | Fatty acid and tocopherol contents of several soybean oils. | 2014 | Nat. Prod. Res. | pmid:24499198 |
| Youn K et al. | Oleic acid and linoleic acid from Tenebrio molitor larvae inhibit BACE1 activity in vitro: molecular docking studies. | 2014 | J Med Food | pmid:24548007 |
| Ambrozova JV et al. | Influence of extractive solvents on lipid and fatty acids content of edible freshwater algal and seaweed products, the green Microalga Chlorella kessleri and the Cyanobacterium Spirulina platensis. | 2014 | Molecules | pmid:24566307 |
| Bazongo P et al. | Characteristics, composition and oxidative stability of Lannea microcarpa seed and seed oil. | 2014 | Molecules | pmid:24566330 |
| Kwon B et al. | Oleate prevents palmitate-induced mitochondrial dysfunction, insulin resistance and inflammatory signaling in neuronal cells. | 2014 | Biochim. Biophys. Acta | pmid:24732014 |
| Nardi F et al. | Enhanced insulin sensitivity associated with provision of mono and polyunsaturated fatty acids in skeletal muscle cells involves counter modulation of PP2A. | 2014 | PLoS ONE | pmid:24632852 |
| Mahendran Y et al. | Association of erythrocyte membrane fatty acids with changes in glycemia and risk of type 2 diabetes. | 2014 | Am. J. Clin. Nutr. | pmid:24153340 |
| Hall TD et al. | Changes during leaf expansion of ΦPSII temperature optima in Gossypium hirsutum are associated with the degree of fatty acid lipid saturation. | 2014 | J. Plant Physiol. | pmid:24594393 |