Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Spaide RF et al. | Characterization of peroxidized lipids in Bruch's membrane. | 1999 | Retina (Philadelphia, Pa.) | pmid:10213241 |
Minich DM et al. | Bile diversion in rats leads to a decreased plasma concentration of linoleic acid which is not due to decreased net intestinal absorption of dietary linoleic acid. | 1999 | Biochim. Biophys. Acta | pmid:10216285 |
Cortez-Pinto H et al. | Lipids up-regulate uncoupling protein 2 expression in rat hepatocytes. | 1999 | Gastroenterology | pmid:10220511 |
Banni S et al. | An increase in vitamin A status by the feeding of conjugated linoleic acid. | 1999 | Nutr Cancer | pmid:10227044 |
Szitanyi P et al. | Metabolism of 13C-labeled linoleic acid in newborn infants during the first week of life. | 1999 | Pediatr. Res. | pmid:10231862 |
Iuliano L et al. | Protection of low density lipoprotein oxidation by the antioxidant agent IRFI005, a new synthetic hydrophilic vitamin E analogue. | 1999 | Free Radic. Biol. Med. | pmid:10232829 |
Burke PA et al. | Conditionally essential fatty acid deficiencies in end-stage liver disease. | 1999 | Nutrition | pmid:10319364 |
Geetha T and Varalakshmi P | Anticomplement activity of triterpenes from Crataeva nurvala stem bark in adjuvant arthritis in rats. | 1999 | Gen. Pharmacol. | pmid:10323491 |
Haggarty P et al. | Effect of maternal polyunsaturated fatty acid concentration on transport by the human placenta. | 1999 | Biol. Neonate | pmid:10325438 |
Wei T et al. | Antioxidant properties of EPC-K1: a study on mechanisms. | 1999 | Biophys. Chem. | pmid:10326248 |