Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Guyenet SJ and Carlson SE | Increase in adipose tissue linoleic acid of US adults in the last half century. | 2015 | Adv Nutr | pmid:26567191 |
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Lee CW et al. | Structural basis for the ligand-binding specificity of fatty acid-binding proteins (pFABP4 and pFABP5) in gentoo penguin. | 2015 | Biochem. Biophys. Res. Commun. | pmid:26206084 |
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Dahlhoff M et al. | EGFR/ERBB receptors differentially modulate sebaceous lipogenesis. | 2015 | FEBS Lett. | pmid:25889637 |
Gouveia-Figueira S et al. | Serum levels of oxylipins in achilles tendinopathy: an exploratory study. | 2015 | PLoS ONE | pmid:25875933 |
Mansour AB et al. | Effect of agricultural sites on differentiation between Chemlali and Neb Jmel olive oils. | 2015 | J Oleo Sci | pmid:25833451 |
Alnaseri H et al. | Inducible Expression of a Resistance-Nodulation-Division-Type Efflux Pump in Staphylococcus aureus Provides Resistance to Linoleic and Arachidonic Acids. | 2015 | J. Bacteriol. | pmid:25802299 |
Fajardo VA et al. | Cardiolipin linoleic acid content and mitochondrial cytochrome c oxidase activity are associated in rat skeletal muscle. | 2015 | Chem. Phys. Lipids | pmid:25727371 |
Chen S et al. | Profiling of volatile compounds and associated gene expression and enzyme activity during fruit development in two cucumber cultivars. | 2015 | PLoS ONE | pmid:25799542 |
Manosalva C et al. | Cloning, identification and functional characterization of bovine free fatty acid receptor-1 (FFAR1/GPR40) in neutrophils. | 2015 | PLoS ONE | pmid:25790461 |
Xing J et al. | Determining antioxidant activities of lactobacilli cell-free supernatants by cellular antioxidant assay: a comparison with traditional methods. | 2015 | PLoS ONE | pmid:25789875 |
Saccenti E et al. | Strategies for individual phenotyping of linoleic and arachidonic acid metabolism using an oral glucose tolerance test. | 2015 | PLoS ONE | pmid:25786212 |
Vlachogianni IC et al. | In vitro assessment of antioxidant activity of tyrosol, resveratrol and their acetylated derivatives. | 2015 | Food Chem | pmid:25660873 |
Yoshida Y et al. | Chemistry of lipid peroxidation products and their use as biomarkers in early detection of diseases. | 2015 | J Oleo Sci | pmid:25766928 |
Ciepiela P et al. | Arachidonic and linoleic acid derivatives impact oocyte ICSI fertilization--a prospective analysis of follicular fluid and a matched oocyte in a 'one follicle--one retrieved oocyte--one resulting embryo' investigational setting. | 2015 | PLoS ONE | pmid:25763593 |
Hernandez LR et al. | Effect of plant growth regulators on fatty acids composition in Jatropha curcas L. callus culture. | 2015 | J Oleo Sci | pmid:25757437 |
Kotani K et al. | Enzymatic preparation of human milk fat substitutes and their oxidation stability. | 2015 | J Oleo Sci | pmid:25757431 |
Hashim RB et al. | Fatty acid compositions of silver catfish, Pangasius sp. farmed in several rivers of Pahang, Malaysia. | 2015 | J Oleo Sci | pmid:25748380 |
Chang TS et al. | Palm oil derived trimethylolpropane triesters synthetic lubricants and usage in industrial metalworking fluid. | 2015 | J Oleo Sci | pmid:25748374 |
Askari M et al. | Tissue fatty acid composition and secretory phospholipase-A2 activity in oral squamous cell carcinoma. | 2015 | Clin Transl Oncol | pmid:25351172 |
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Perumalsamy H et al. | Larvicidal activity and possible mode of action of four flavonoids and two fatty acids identified in Millettia pinnata seed toward three mosquito species. | 2015 | Parasit Vectors | pmid:25928224 |
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Nakahashi H et al. | Evaluation of the Key Odorants in Volatile Oils from Tubers of Apios americana Medikus. | 2015 | J Oleo Sci | pmid:26521814 |
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