| MeSH term | MeSH ID | Detail |
|---|---|---|
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Kidney Diseases | D007674 | 29 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Metabolism, Inborn Errors | D008661 | 46 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
Linoleic acid
Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoleic acid?
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoleic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with Linoleic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoleic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoleic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoleic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hu ZY et al. | cAMP inhibits linoleic acid-induced growth by antagonizing p27(kip1) depletion, but not interfering with the extracellular signal-regulated kinase or AP-1 activities. | 1998 | Biochim. Biophys. Acta | pmid:9784625 |
| Turpeinen AM et al. | Replacement of dietary saturated by unsaturated fatty acids: effects of platelet protein kinase C activity, urinary content of 2,3-dinor-TXB2 and in vitro platelet aggregation in healthy man. | 1998 | Thromb. Haemost. | pmid:9798986 |
| Bretillon L et al. | Desaturation and chain elongation of [1-14C]mono-trans isomers of linoleic and alpha-linolenic acids in perfused rat liver. | 1998 | J. Lipid Res. | pmid:9799809 |
| Cunnane SC et al. | Substantial carbon recycling from linoleate into products of de novo lipogenesis occurs in rat liver even under conditions of extreme dietary linoleate deficiency. | 1998 | J. Lipid Res. | pmid:9799813 |
| Masia A et al. | Enrichment with a polyunsaturated fatty acid enhances the survival of Saccharomyces cerevisiae in the presence of tributyltin. | 1998 | FEMS Microbiol. Lett. | pmid:9809434 |
| Broun P et al. | Catalytic plasticity of fatty acid modification enzymes underlying chemical diversity of plant lipids. | 1998 | Science | pmid:9812895 |
| Morita Y et al. | Involvement of lipid peroxidation in free fatty acid-induced isolated rat pancreatic acinar cell injury. | 1998 | Pancreas | pmid:9821180 |
| Gu JY et al. | Effect of dietary fats and sesamin on the lipid metabolism and immune function of Sprague-Dawley rats. | 1998 | Biosci. Biotechnol. Biochem. | pmid:9836427 |
| Iwase H et al. | Calcium is required for quasi-lipoxygenase activity of hemoproteins. | 1998 | Free Radic. Biol. Med. | pmid:9840740 |
| Phifer CB and Berthoud HR | Duodenal nutrient infusions differentially affect sham feeding and Fos expression in rat brain stem. | 1998 | Am. J. Physiol. | pmid:9841547 |
| Turpeinen AM et al. | A high linoleic acid diet increases oxidative stress in vivo and affects nitric oxide metabolism in humans. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9844997 |
| Oyama Y et al. | Protective actions of 5'-n-alkylated curcumins on living cells suffering from oxidative stress. | 1998 | Eur. J. Pharmacol. | pmid:9845274 |
| Nestel PJ et al. | Effect of a stearic acid-rich, structured triacylglycerol on plasma lipid concentrations. | 1998 | Am. J. Clin. Nutr. | pmid:9846846 |
| Spiteller G | Linoleic acid peroxidation--the dominant lipid peroxidation process in low density lipoprotein--and its relationship to chronic diseases. | 1998 | Chem. Phys. Lipids | pmid:9853364 |
| Jarmuszkiewicz W et al. | Linoleic acid-induced activity of plant uncoupling mitochondrial protein in purified tomato fruit mitochondria during resting, phosphorylating, and progressively uncoupled respiration. | 1998 | J. Biol. Chem. | pmid:9857016 |
| Hudson JA et al. | Hydration of linoleic acid by bacteria isolated from ruminants. | 1998 | FEMS Microbiol. Lett. | pmid:9868771 |
| Blaauwwiekel EE et al. | Apolipoprotein E genotype is a determinant of low-density lipoprotein cholesterol and of its response to a low-cholesterol diet in Type 1 diabetic patients with elevated urinary albumin excretion. | 1998 | Diabet. Med. | pmid:9868977 |
| Kim EJ et al. | Development of a serum-free medium for the production of humanized antibody from Chinese hamster ovary cells using a statistical design. | 1998 Nov-Dec | In Vitro Cell. Dev. Biol. Anim. | pmid:9870524 |
| Akeo K and Hiramitsu T | Changes in lipid peroxide level in retinal pigment epithelial cells in vitro upon addition of linoleic acids or linoleic acid hydroperoxides under varying concentrations of oxygen. | 1998 | Pigment Cell Res. | pmid:9877104 |
| Tsimikas S et al. | LDL isolated from Greek subjects on a typical diet or from American subjects on an oleate-supplemented diet induces less monocyte chemotaxis and adhesion when exposed to oxidative stress. | 1999 | Arterioscler. Thromb. Vasc. Biol. | pmid:9888874 |