| MeSH term | MeSH ID | Detail |
|---|---|---|
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Kidney Diseases | D007674 | 29 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Metabolism, Inborn Errors | D008661 | 46 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
Linoleic acid
Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoleic acid?
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoleic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with Linoleic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoleic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoleic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoleic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yen GC and Chuang DY | Antioxidant properties of water extracts from Cassia tora L. in relation to the degree of roasting. | 2000 | J. Agric. Food Chem. | pmid:10898619 |
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| Vanella A et al. | L -propionyl-carnitine as superoxide scavenger, antioxidant, and DNA cleavage protector. | 2000 | Cell Biol. Toxicol. | pmid:10917565 |
| Jones S et al. | Isomers of conjugated linoleic acid (CLA) are incorporated into egg yolk lipids by CLA-fed laying hens. | 2000 | J. Nutr. | pmid:10917915 |
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| Viola G et al. | In vitro studies of the phototoxic potential of the antidepressant drugs amitriptyline and imipramine. | 2000 | Farmaco | pmid:10919085 |
| Ip C et al. | Induction of apoptosis by conjugated linoleic acid in cultured mammary tumor cells and premalignant lesions of the rat mammary gland. | 2000 | Cancer Epidemiol. Biomarkers Prev. | pmid:10919739 |
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| Griinari JM et al. | Conjugated linoleic acid is synthesized endogenously in lactating dairy cows by Delta(9)-desaturase. | 2000 | J. Nutr. | pmid:10958825 |
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| Monteggia E et al. | Phospholipid distribution in murine mammary adenocarcinomas induced by activated neu oncogene. | 2000 | Cancer Detect. Prev. | pmid:10975281 |
| Kajita M et al. | Enhanced enteral bioavailability of vancomycin using water-in-oil-in-water multiple emulsion incorporating highly purified unsaturated fatty acid. | 2000 | J Pharm Sci | pmid:10980499 |
| Oak J et al. | Synthetically prepared Aamadori-glycated phosphatidylethanolaminecan trigger lipid peroxidation via free radical reactions. | 2000 | FEBS Lett. | pmid:10984609 |
| O'Quinn PR et al. | Effects of modified tall oil versus a commercial source of conjugated linoleic acid and increasing levels of modified tall oil on growth performance and carcass characteristics of growing-finishing pigs. | 2000 | J. Anim. Sci. | pmid:10985411 |
| Hover CG and Kulkarni AP | Human term placental lipoxygenase-mediated N-demethylation of phenothiazines and insecticides in the presence of linoleic acid. | 2000 | Placenta | pmid:10985967 |
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| Horrobin DF | Commentary on the workshop statement: are we really sure that arachidonic acid and linoleic acid are bad things? | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10991771 |
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| Antony SM et al. | Antioxidative effect of maillard reaction products formed from honey at different reaction times. | 2000 | J. Agric. Food Chem. | pmid:10995301 |
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| Han KH et al. | Oxidized LDL reduces monocyte CCR2 expression through pathways involving peroxisome proliferator-activated receptor gamma. | 2000 | J. Clin. Invest. | pmid:10995790 |
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| Jones DF et al. | Short communication: influence of dietary tallow and fish oil on milk fat composition. | 2000 | J. Dairy Sci. | pmid:11003234 |
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| Lucchi L et al. | Changes in conjugated linoleic acid and its metabolites in patients with chronic renal failure. | 2000 | Kidney Int. | pmid:11012903 |
| Petrik MB et al. | Highly unsaturated (n-3) fatty acids, but not alpha-linolenic, conjugated linoleic or gamma-linolenic acids, reduce tumorigenesis in Apc(Min/+) mice. | 2000 | J. Nutr. | pmid:11015469 |
| West DB et al. | Conjugated linoleic acid persistently increases total energy expenditure in AKR/J mice without increasing uncoupling protein gene expression. | 2000 | J. Nutr. | pmid:11015475 |
| Qian SY et al. | EPR detection of lipid-derived free radicals from PUFA, LDL, and cell oxidations. | 2000 | Free Radic. Biol. Med. | pmid:11025200 |
| Meaney CM and O'Driscoll CM | A comparison of the permeation enhancement potential of simple bile salt and mixed bile salt:fatty acid micellar systems using the CaCo-2 cell culture model. | 2000 | Int J Pharm | pmid:11036226 |
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| Kwok CF et al. | Linoleic acid and oleic acid increase the endothelin-1 binding and action in cultured rat aortic smooth muscle cells. | 2000 | Metab. Clin. Exp. | pmid:11092498 |
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| Yamasaki M et al. | Dietary conjugated linoleic acid increases immunoglobulin productivity of Sprague-Dawley rat spleen lymphocytes. | 2000 | Biosci. Biotechnol. Biochem. | pmid:11129589 |
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| Kawai T et al. | Chronic effects of different fatty acids and leptin in INS-1 cells. | 2001 | Diabetes Res. Clin. Pract. | pmid:11137176 |
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| Sakuma S et al. | The effects of fatty acyl CoA esters on the formation of prostaglandin and arachidonoyl-CoA formed from arachidonic acid in rabbit kidney medulla microsomes. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11161586 |
| Soppela P and Nieminen M | The effect of wintertime undernutrition on the fatty acid composition of leg bone marrow fats in reindeer (Rangifer tarandus tarandus L.). | 2001 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:11163305 |
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| RamÃrez-Expósito MJ et al. | Oleate, linoleate and cholesterol differently modify aspartyl- and glutamyl-aminopeptidase activities in primary cultures of rat astrocytes. | 2001 | Comp. Biochem. Physiol. C Toxicol. Pharmacol. | pmid:11166679 |
| Widstrom RL et al. | Binding of cytochrome P450 monooxygenase and lipoxygenase pathway products by heart fatty acid-binding protein. | 2001 | Biochemistry | pmid:11170430 |
| Rival SG et al. | Caseins and casein hydrolysates. 2. Antioxidative properties and relevance to lipoxygenase inhibition. | 2001 | J. Agric. Food Chem. | pmid:11170591 |
| López-Nicolás JM et al. | Eggplant lipoxygenase (Solanum melongena): product characterization and effect of physicochemical properties of linoleic acid on the enzymatic activity. | 2001 | J. Agric. Food Chem. | pmid:11170610 |
| Louet JF et al. | Long-chain fatty acids regulate liver carnitine palmitoyltransferase I gene (L-CPT I) expression through a peroxisome-proliferator-activated receptor alpha (PPARalpha)-independent pathway. | 2001 | Biochem. J. | pmid:11171094 |
| Kaushik N and Agnihotri A | GLC analysis of Indian rapeseed-mustard to study the variability of fatty acid composition. | 2000 | Biochem. Soc. Trans. | pmid:11171132 |
| Verwoert I et al. | The molecular basis of the high linoleic acid content in Petunia seed oil: analysis of a seed-specific linoleic acid mutant. | 2000 | Biochem. Soc. Trans. | pmid:11171150 |
| Kamisaka Y and Noda N | Intracellular transport of phosphatidic acid and phosphatidylcholine into lipid bodies: use of fluorescent lipids to study lipid-body formation in an oleaginous fungus. | 2000 | Biochem. Soc. Trans. | pmid:11171185 |
| Grechkin AN et al. | Lipoxygenase pathway in tulip: biosynthesis of ketols. | 2000 | Biochem. Soc. Trans. | pmid:11171230 |