| MeSH term | MeSH ID | Detail |
|---|---|---|
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Kidney Diseases | D007674 | 29 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Metabolism, Inborn Errors | D008661 | 46 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
Linoleic acid
Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoleic acid?
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoleic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with Linoleic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoleic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoleic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoleic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Dokko RC et al. | Cellular uptake of stearic, oleic, linoleic, and linolenic acid and their effects on synthesis and secretion of lipids in Hep-G2 cells. | 1998 | Int. J. Biochem. Cell Biol. | pmid:9597754 |
| Kambayashi Y et al. | Preferential hydrolysis of oxidized phosphatidylcholine in cholesterol-containing phosphatidylcholine liposome by phospholipase A2. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9588178 |
| Peterson DB | Long-chain fatty acids and cardiovascular disease risk in non-insulin-dependent diabetes. | 1998 | Nutrition | pmid:9583379 |
| Hamberg M et al. | Manganese lipoxygenase. Discovery of a bis-allylic hydroperoxide as product and intermediate in a lipoxygenase reaction. | 1998 | J. Biol. Chem. | pmid:9582346 |
| Lee M et al. | Identification of non-heme diiron proteins that catalyze triple bond and epoxy group formation. | 1998 | Science | pmid:9572738 |
| Hill EM et al. | Changes in expression of 15-lipoxygenase and prostaglandin-H synthase during differentiation of human tracheobronchial epithelial cells. | 1998 | Am. J. Respir. Cell Mol. Biol. | pmid:9569236 |
| Kelly ML et al. | Dietary fatty acid sources affect conjugated linoleic acid concentrations in milk from lactating dairy cows. | 1998 | J. Nutr. | pmid:9566998 |
| Marra F et al. | Effects of supplementation with unsaturated fatty acids on plasma and membrane lipid composition and platelet function in patients with cirrhosis and defective aggregation. | 1998 | J. Hepatol. | pmid:9566835 |
| Yehuda S et al. | Modulation of learning and neuronal membrane composition in the rat by essential fatty acid preparation: time-course analysis. | 1998 | Neurochem. Res. | pmid:9566600 |
| Kowaltowski AJ et al. | Activation of the potato plant uncoupling mitochondrial protein inhibits reactive oxygen species generation by the respiratory chain. | 1998 | FEBS Lett. | pmid:9559650 |
| Akamatsu H and Horio T | The possible role of reactive oxygen species generated by neutrophils in mediating acne inflammation. | 1998 | Dermatology (Basel) | pmid:9557235 |
| Rosenfield RL et al. | Mechanisms of androgen induction of sebocyte differentiation. | 1998 | Dermatology (Basel) | pmid:9557223 |
| Mennen L et al. | Factor VIIa response to a fat-rich meal does not depend on fatty acid composition: a randomized controlled trial. | 1998 | Arterioscler. Thromb. Vasc. Biol. | pmid:9555866 |
| Kataoka K et al. | Pathophysiologic studies of experimental chronic pancreatitis in rats induced by injection of zein-oleic acid-linoleic acid solution into the pancreatic duct. | 1998 | Pancreas | pmid:9548669 |
| Li-Stiles B et al. | Identification and characterization of several forms of phospholipase A2 in mouse epidermal keratinocytes. | 1998 | J. Lipid Res. | pmid:9548589 |
| Liu SX et al. | Oxidized cholesterol in oxidized low density lipoprotein may be responsible for the inhibition of LPS-induced nitric oxide production in macrophages. | 1998 | Atherosclerosis | pmid:9544730 |
| Matthys LA and Widmaier EP | Fatty acids inhibit adrenocorticotropin-induced adrenal steroidogenesis. | 1998 | Horm. Metab. Res. | pmid:9543689 |
| Voskuyl RA et al. | Anticonvulsant effect of polyunsaturated fatty acids in rats, using the cortical stimulation model. | 1998 | Eur. J. Pharmacol. | pmid:9543232 |
| Herrera JA et al. | Prevention of preeclampsia by linoleic acid and calcium supplementation: a randomized controlled trial. | 1998 | Obstet Gynecol | pmid:9540946 |
| Liang JF and Akaike T | Protective effect of linoleic acid on IFN gamma-induced cellular injury in primary culture hepatocytes. | 1998 | J. Biochem. | pmid:9538194 |